Intervention
Interventional neuroradiology may play an important role in the future treatment of astrocytoma with intratumoral chemotherapy. In general, current treatment is limited to traditional approaches.
Medicolegal Pitfalls
- Medical and legal pitfalls of imaging of astrocytoma primarily consist of missed or delayed diagnosis.
- With CT, the scarcity of edema and mass effect with low-grade lesions may make the true extent of pathology difficult to ascertain. Furthermore, small lesions may not be visible if contrast material is not used.
- As many as 4% of grade III or IV lesions do not enhance on imaging.
- Finally, because of the inhomogeneity of high-grade tumors, stereotactic biopsy of an area of necrosis instead of the tumor can delay accurate diagnosis.
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References
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Further Reading
Keywords
primary intra-axial brain tumors, primary intraaxial brain tumors, gliomas, supratentorial tumors, grade I astrocytomas, pilocytic astrocytoma, subependymal giant cell astrocytoma, giant-cell astrocytoma, pleomorphic xanthoastrocytoma, grade II astrocytomas, protoplasmic astrocytomas, gemistocytic astrocytomas, fibrillary astrocytomas, grade III astrocytomas, anaplastic astrocytomas, grade IV astrocytomas, glioblastoma multiforme, GBM, giant cell glioblastomas, giant-cell glioblastomas, gliosarcoma variants, low-grade astrocytomas, PTEN/MMAC1, DMBT1, EGFR, p53, TP53, p16, PDGFR, retinoblastoma cell-cycle regulatory genes
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