eMedicine Specialties > Radiology > Brain/Spine

Astrocytoma, Brain: Follow-up

Author: Felice J Esposito, DO, Staff Physician, Department of Radiology, Mercy Catholic Medical Center
Coauthor(s): Rajesh Mithalal, MD, Resident Physician, Department of Radiology, Mercy Catholic Medical Center; Michele Papa, MD, Professor, Department of Neuroanatomy, Second University of Naples, Italy; Mimi Huynh Pinto, DO, Resident Physician, Department of Radiology, Mercy Catholic Medical Center; Djamil Fertikh, MD, Attending Physician, Division of Radiology, Association of Alexandria Radiologists; Michael L Brooks, MD, JD, FCLM, Clinical Associate Professor of Radiology, Drexel University School of Medicine; Adjunct Associate Professor of Radiology, Philadelphia College of Osteopathic Medicine; Director of Neuroradiology, Mercy Diagnostic Imaging
Contributor Information and Disclosures

Updated: Nov 11, 2009

Intervention

Interventional neuroradiology may play an important role in the future treatment of astrocytoma with intratumoral chemotherapy. In general, current treatment is limited to traditional approaches.

Medicolegal Pitfalls

  • Medical and legal pitfalls of imaging of astrocytoma primarily consist of missed or delayed diagnosis.
  • With CT, the scarcity of edema and mass effect with low-grade lesions may make the true extent of pathology difficult to ascertain. Furthermore, small lesions may not be visible if contrast material is not used.
  • As many as 4% of grade III or IV lesions do not enhance on imaging.
  • Finally, because of the inhomogeneity of high-grade tumors, stereotactic biopsy of an area of necrosis instead of the tumor can delay accurate diagnosis.
 


More on Astrocytoma, Brain

Overview: Astrocytoma, Brain
Imaging: Astrocytoma, Brain
Follow-up: Astrocytoma, Brain
Multimedia: Astrocytoma, Brain
References
Further Reading
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References

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  3. Decker Y, McBean G, Godson C. Lipoxin A4 inhibits IL-1{beta}-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells. Am J Physiol Cell Physiol. Apr 8 2009;[Medline].

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Further Reading

Clinical guidelines
Radiotherapy for newly diagnosed malignant glioma in adults: a clinical practice guideline.
Program in Evidence-based Care - State/Local Government Agency [Non-U.S.].  2000 Sep 19 (revised 2005 Nov 2).  32 pages.  NGC:004954

Gliadel wafers in the treatment of malignant glioma: a clinical practice guideline.
Program in Evidence-based Care - State/Local Government Agency [Non-U.S.].  2006 Aug 15.  19 pages.  NGC:005649

Adjuvant systemic chemotherapy, following surgery and external beam radiotherapy, for adults with newly diagnosed malignant glioma: a clinical practice guideline.
Program in Evidence-based Care - State/Local Government Agency [Non-U.S.].  2004 Mar 10 (revised 2006 May 8).  23 pages.  NGC:005092

Clinical trials

Intracerebral Clysis in Treating Patients With Recurrent Primary Brain Tumors

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Antineoplaston Therapy in Treating Children With Low-Grade Astrocytoma


Related eMedicine topics

Astrocytoma   (Pediatrics)

Glioblastoma Multiforme (Neurology)

Glioblastoma Multiforme (Radiology)

Glioblastoma Multiforme (Oncology)

Low-Grade Astrocytoma


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Keywords

brain astrocytoma, primary intra-axial brain tumors, primary intraaxial brain tumors, gliomas, supratentorial tumors, grade I astrocytomas, pilocytic astrocytoma, subependymal giant cell astrocytoma, giant-cell astrocytoma, pleomorphic xanthoastrocytoma, grade II astrocytomas, protoplasmic astrocytomas, gemistocytic astrocytomas, fibrillary astrocytomas, grade III astrocytomas, anaplastic astrocytomas, grade IV astrocytomas, glioblastoma multiforme, GBM, giant cell glioblastomas, giant-cell glioblastomas, gliosarcoma variants, low-grade astrocytomas, PTEN/MMAC1, DMBT1, EGFR, p53, TP53, p16, PDGFR, retinoblastoma cell-cycle regulatory genes

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Contributor Information and Disclosures

Author

Felice J Esposito, DO, Staff Physician, Department of Radiology, Mercy Catholic Medical Center
Felice J Esposito, DO is a member of the following medical societies: American College of Radiology, American Medical Association, American Osteopathic Association, American Roentgen Ray Society, and Pennsylvania Medical Society
Disclosure: Nothing to disclose.

Coauthor(s)

Rajesh Mithalal, MD, Resident Physician, Department of Radiology, Mercy Catholic Medical Center
Disclosure: Nothing to disclose.

Michele Papa, MD, Professor, Department of Neuroanatomy, Second University of Naples, Italy
Disclosure: Nothing to disclose.

Mimi Huynh Pinto, DO, Resident Physician, Department of Radiology, Mercy Catholic Medical Center
Mimi Huynh Pinto, DO is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, Pennsylvania Radiological Society, and Radiological Society of North America
Disclosure: Nothing to disclose.

Djamil Fertikh, MD, Attending Physician, Division of Radiology, Association of Alexandria Radiologists
Djamil Fertikh, MD is a member of the following medical societies: American College of Radiology, American Medical Association, American Society of Neuroradiology, and Radiological Society of North America
Disclosure: Nothing to disclose.

Michael L Brooks, MD, JD, FCLM, Clinical Associate Professor of Radiology, Drexel University School of Medicine; Adjunct Associate Professor of Radiology, Philadelphia College of Osteopathic Medicine; Director of Neuroradiology, Mercy Diagnostic Imaging
Michael L Brooks, MD, JD, FCLM is a member of the following medical societies: American College of Legal Medicine, American College of Radiology, American Society of Neuroradiology, American Society of Pediatric Neuroradiology, and American Society of Spine Radiology
Disclosure: Nothing to disclose.

Medical Editor

Chi-Shing Zee, MD, Chief of Neuroradiology, Professor, Departments of Radiology and Neurosurgery, University of Southern California School of Medicine
Chi-Shing Zee, MD is a member of the following medical societies: American Society of Neuroradiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Val Runge, MD, Robert and Alma Moreton Centennial Chair in Radiology, Professor, Editor-in-Chief of Investigative Radiology, Department of Radiology, Scott and White Clinic and Hospital
Val Runge, MD is a member of the following medical societies: Society for Health and Human Values
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

L Gill Naul, MD, Professor and Head, Department of Radiology, Texas A&M University College of Medicine; Chair, Department of Radiology, Chief, Section of Magnetic Resonance Imaging, Scott and White Memorial Hospital and Clinic
L Gill Naul, MD is a member of the following medical societies: American College of Radiology, American Medical Association, American Roentgen Ray Society, Radiological Society of North America, and Texas Medical Association
Disclosure: Nothing to disclose.

 
 
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