Multimedia
 | Media file 1: Pathology of chordoma. Lobulated tumor with epithelial cords separated by mucinous material (hematoxylin-phloxine-saffron, magnification X25). |
 | Media file 2: Pathology of chordoma. At higher magnification, vacuolated neoplastic cells and occasional physaliphorous cells are observed (hematoxylin-phloxine-saffron, magnification X225). |
 | Media file 3: Immunopathology of chordoma. The epithelial nature of chordoma is assessed by the strong immunoreactivity to anticytokeratin antibody (immunoperoxidase, magnification X130). |
 | Media file 4: Topography of chordoma. Differential diagnosis between chordoma and chondroma. 4a. Clival chordoma with a lateral extension to the left cavernous sinus. Coronal contrast-enhanced T1-weighted spin-echo image. The tumor is median with a lateral extension. 4b. Laterosellar chondroma. Coronal contrast-enhanced T1-weighted gradient-echo image demonstrates the strictly lateral localization of the tumor. |
 | Media file 5: Morphology of chordoma. Chordoma of the upper part of the clivus with posterior extension to the pontine cistern. Contrast-enhanced sagittal T1-weighted spin-echo image. The bone appears expanded in this early form. |
 | Media file 6: Differential diagnosis between chordoma and invasive pituitary adenoma. Sagittal contrast-enhanced T1-weighted magnetic resonance image. 6a. Clivus chordoma with posterior extension into pontine cistern and compression of brainstem. The tumor appears lobulated and enhances heterogeneously, while the pituitary gland shows more marked enhancement, suggesting that the tumor does not arise from it. 6b. Invasive pituitary adenoma. The signal of the mass in the sphenoid is not homogeneous. No posterior extension is observed; extension is mostly into the sphenoid sinus. The pituitary gland is not visible. |
 | Media file 7: Recurrence of clival chordoma following surgery. Contrast-enhanced sagittal T1-weighted gradient-echo image showing brainstem and foramen magnum invasion. |
 | Media file 8: Chordoma. Coronal T1-weighted spin-echo magnetic resonance image. High signal is a result of hemorrhage. |
 | Media file 9: Chordoma. Contrast-enhanced sagittal gradient-echo T1-weighted magnetic resonance image demonstrates heterogeneous, lobulated tumor. |
 | Media file 10: Computed tomography (CT) scan of 2 patients with chordoma. Coronal plane (left): midline tumor with lateral extension, skull base destruction, and carotid canal lysis on the right. Note calcification or osseous debris. Axial plane (right): lysis of clivus (arrow). |
 | Media file 11: Sacrococcygeal chordoma. Plain radiograph of the pelvis showing expansion of the sacrum, bone rarefaction, and large mass of soft tissue with some trabeculations. |
 | Media file 12: Coccygeal chordoma. Sagittal T1-weighted magnetic resonance image. Note the subcutaneous tissue infiltration. |
 | Media file 13: Sagittal contrast-enhanced T1-weighted magnetic resonance image. Note the heterogeneous gadolinium enhancement (same patient as in Image 12). |
 | Media file 14: Sagittal T2-weighted magnetic resonance image. The tumor appears lobulated and shows high signal (same patient as in Images 12 and 13). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 15: Sacrococcygeal chordoma. Sagittal T1-weighted magnetic resonance image showing a huge, well-delineated tumoral mass invading the sacral canal, extending into the pelvis, and shifting the fat, uterus, bladder, and rectum. Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 16: Sagittal contrast-enhanced T1-weighted magnetic resonance image. Note the lobulated heterogeneous contrast enhancement (same patient as in Image 15). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 17: Coronal T1-weighted magnetic resonance image (same patient as in Images 15 and 16). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 18: Coronal contrast-enhanced T1-weighted magnetic resonance image (same patient as in Images 15-17). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 19: Computed tomography (CT) scan. Note the calcification (same patient as in Images 15-18). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 20: Computed tomography (CT) scan. Recurrence of a sacrococcygeal chordoma. Note tumoral infiltration of gluteal muscles displacing the rectum anteriorly. Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 21: Coronal T1-weighted magnetic resonance image. Tumoral infiltration of the thigh (same patient as in Image 20). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 22: Axial T1-weighted magnetic resonance image (same patient as in Images 20 and 21). Image courtesy of Editions Masson, Paris, 2002. |
 | Media file 23: Computed tomography (CT) scan of sacrococcygeal chordoma. Note the sacral lysis with trabeculations. |
 | Media file 24: Computed tomography (CT) scan of sacrococcygeal chordoma. Note the tumoral calcification in this huge pelvic tumor. |
 | Media file 25: Computed tomography (CT) scan of sacrococcygeal chordoma. Note the right sacroiliac joint lysis. |
More on Chordoma |
| Overview: Chordoma |
| Imaging: Chordoma |
| Follow-up: Chordoma |
 Multimedia: Chordoma |
| References |
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Further Reading
Keywords
chordoma, notochord tumor, primitive notochord tumor, notochord mass, intracranial tumor, intracranial mass
