eMedicine Specialties > Radiology > Brain/Spine
Multiple Sclerosis, Spine: Multimedia
Updated: May 24, 2008
Multimedia
![]() | Media file 1: Sagittal, T2-weighted magnetic resonance image of the cervical spinal cord in a 27-year-old woman showing a fusiform area of increased signal intensity representing a multiple sclerosis plaque. Same patient as in Image 2. |
![]() | Media file 2: Corresponding axial, T2-weighted magnetic resonance image in a 27-year-old woman showing a multiple sclerosis plaque located in the left dorsolateral region of the left hemicord. Same patient as in Image 1. |
![]() | Media file 3: Sagittal, T2-weighted image showing areas of signal hyperintensity in the cervical spinal cord and pons. Same patient as in Images 4-5. |
![]() | Media file 4: Corresponding axial, T2-weighted image showing a large area of signal hyperintensity in the right lateral aspect of the cord. Same patient as in Images 3 and 5. |
![]() | Media file 5: Sagittal, T1-weighted image following gadolinium contrast showing arciform enhancement along the edge of the plaque, typical of demyelination. Same patient as in Images 3-4. |
![]() | Media file 6: Gadolinium-enhanced, T1-weighted image showing enhancement of the left optic nerve (arrow). Same patient as in Image 7. |
![]() | Media file 7: Corresponding axial images of the spinal cord showing enhancing plaque (arrow). The combination of optic neuritis and spinal cord lesion constitutes Devic neuromyelitis optica. Same patient as in Image 6. |
![]() | Media file 8: Sagittal, T2-weighted image showing a focal area of spinal cord atrophy in a patient with long-standing multiple sclerosis. |
More on Multiple Sclerosis, Spine |
| Overview: Multiple Sclerosis, Spine |
| Imaging: Multiple Sclerosis, Spine |
| Follow-up: Multiple Sclerosis, Spine |
Multimedia: Multiple Sclerosis, Spine |
| References |
| « Previous Page |
References
Noseworthy JH, Lucchinetti C, Rodriguez M, et al. Multiple sclerosis. N Engl J Med. Sep 28 2000;343(13):938-52. [Medline].
Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol. Sci. 2001;22 (2):117–39. [Medline].
Parry-Jones AR, Mitchell JD, Gunarwardena WJ, et al. Leber's hereditary optic neuropathy associated with multiple sclerosis: Harding's syndrome. Pract Neurol. Apr 2008;8(2):118-21. [Medline].
Grossman RI, Yousem DM. Neuroradiology: The Requisites. St Louis, Mo: Mosby-Year Book; 1994.
Rovira-Canellas A, Alonso-Farre J, Rio-Izquierdo J. [Magnetic resonance in the clinical and therapeutic follow-up of multiple sclerosis]. Rev Neurol. May 16-31 2000;30(10):980-5. [Medline].
Agosta F, Absinta M, Sormani MP, et al. In vivo assessment of cervical cord damage in MS patients: a longitudinal diffusion tensor MRI study. Brain. Aug 2007;130:2211-9. [Medline].
LM Tartaglino, DP Friedman, AE Flanders, et al. Multiple sclerosis in the spinal cord: MR appearance and correlation with clinical parameters. Radiology. 1995;Vol 195:725-32. [Medline]. [Full Text].
Filippi M. Enhanced magnetic resonance imaging in multiple sclerosis. Mult Scler. Oct 2000;6(5):320-6. [Medline].
Grossman RI, Barkhof F, Filippi M. Assessment of spinal cord damage in MS using MRI. J Neurol Sci. Jan 15 2000;172 Suppl 1:S36-9. [Medline].
Henning A, Schär M, Kollias SS, et al. Quantitative magnetic resonance spectroscopy in the entire human cervical spinal cord and beyond at 3T. Magn Reson Med. Apr 17 2008;[Medline].
Marliani AF, Clementi V, Albini-Riccioli L, et al. Quantitative proton magnetic resonance spectroscopy of the human cervical spinal cord at 3 Tesla. Magn Reson Med. Jan 2007;57(1):160-3. [Medline].
Filippi M, Yousry TA, Alkadhi H, et al. Spinal cord MRI in multiple sclerosis with multicoil arrays: a comparison between fast spin echo and fast FLAIR. J Neurol Neurosurg Psychiatry. Dec 1996;61(6):632-5. [Medline]. [Full Text].
Hittmair K, Mallek R, Prayer D, et al. Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences. AJNR Am J Neuroradiol. Sep 1996;17(8):1555-65. [Medline]. [Full Text].
Stevenson VL, Gawne-Cain ML, Barker GJ, et al. Imaging of the spinal cord and brain in multiple sclerosis: a comparative study between fast FLAIR and fast spin echo. J Neurol. Feb 1997;244(2):119-24. [Medline].
Filippi M, Bozzali M, Horsfield MA, et al. A conventional and magnetization transfer MRI study of the cervical cord in patients with MS. Neurology. Jan 11 2000;54(1):207-13. [Medline].
Finelli DA, Hurst GC, Karaman BA, et al. Use of magnetization transfer for improved contrast on gradient-echo MR images of the cervical spine. Radiology. Oct 1994;193(1):165-71. [Medline]. [Full Text].
Rocca MA, Mastronardo G, Horsfield MA, et al. Comparison of three MR sequences for the detection of cervical cord lesions in patients with multiple sclerosis. AJNR Am J Neuroradiol. Oct 1999;20(9):1710-6. [Medline]. [Full Text].
Poonawalla AH, Hou P, Nelson FA, et al. Cervical spinal cord lesions in multiple sclerosis: T1-weighted inversion-recovery MR imaging with phase-sensitive reconstruction. Radiology. Jan 2008;246(1):258-64. [Medline]. [Full Text].
Further Reading
Keywords
multiple sclerosis, spinal multiple sclerosis, multiple sclerosis of the spine, demyelinating process, brain lesions, spine lesions, perivenular inflammation, plaques, fibrillary gliosis, oligodendroglia, spinal MS, spinal multiple sclerosis, Devic neuromyelitis optica, optic neuritis
















Multimedia: Multiple Sclerosis, Spine