eMedicine Specialties > Radiology > Brain/Spine
Neurofibromatosis Type 1: Multimedia
Updated: Jan 23, 2008
Multimedia
 | Media file 1: Frontal skull radiograph in a patient with NF1 shows asymmetry of the orbits but a normal sphenoid ridge. |
 | Media file 2: Plain radiograph in a patient with NF1 shows a left lambdoid defect (same patient as in Image 1). |
 | Media file 3: (Left) Plain radiograph of the left forearm in a 15-year-old boy shows hypoplasia and deformity of the radius and ulna. Note the intramedullary sclerotic streaks within the radius and periosteal dysplasia. (Right) Compare these findings with the normal right forearm, and note the unrelated exostosis of the distal radius. |
 | Media file 4: Chest radiograph in a 56-year-old man with NF1 shows apical neurofibromas and ribbon or notched ribs. Note the myodil within the spinal canal from a previous myelography performed because of previous spinal root problems. Myodil or Pantopaque (iophendylate) is an oily contrast medium that was used for myelography in the 1960s and 1970s, but its use was abandoned because of the risk of arachnoiditis. |
 | Media file 5: Chest radiograph in a 62-year-old patient with NF1 shows interstitial fibrosis in the middle and lower zones. Note the multiple surface neurofibromas. |
 | Media file 6: Plain radiograph of the pelvis in a 28-year-old woman shows gross deformity of the left hemipelvis and the left upper femur. |
 | Media file 7: Sagittal T1-weighted unenhanced MRI scan in a 28-year-old woman shows dural ectasia and a large lobulated anterior sacral meningocele (M) (same patient as in Image 6). |
 | Media file 8: Sagittal T2-weighted MRI in a 28-year-old woman shows dural ectasia and a large lobulated anterior meningocele (same patient as in Images 6-7). |
 | Media file 9: A 66-year-old woman with NF1 presented with paresthesia down the right arm. T1-weighted transaxial MRI through the cervical spine shows a low-signal-intensity mass extruding through the right foraminal canal at the C5-6 vertebral level; the mass appears to be eroding the vertebral body. The final diagnosis was a neurofibroma. |
 | Media file 10: T2-weighted transaxial MRI in a 66-year-old woman shows a moderately hyperintense neurofibroma (N) (same patient as in Image 9). |
 | Media file 11: CT scan through the orbits in a patient with NF1 shows a right optic glioma. |
 | Media file 12: A 7-year-old girl with a family history of NF1 had been blind for 18 months. T2-weighted transaxial MRI shows bilateral optic nerve gliomas (arrows), as well as a right temporal lobe and left brainstem lesions, which may represent additional gliomas or spongiform white matter changes of NF1. |
 | Media file 13: T1-weighted MRI in a 7-year-old girl with a family history of NF1 who had been blind for 18 months shows bilateral optic nerve gliomas (arrows) (same patient as in Image 12). |
 | Media file 14: Axial sonogram through the right iliac fossa in a 28-year-old man with NF1shows a hypoechoic dumbbell-shaped neurofibroma. |
 | Media file 15: T1-weighted coronal MRI of the abdomen in a 28-year-old man shows a low-signal dumbbell-shaped right iliac fossa tumor, confirmed to be a neurofibroma at laparotomy (same patient as in Image 14). The patient also had sickle cell trait and presented with hematuria from a left-sided medullary cell renal carcinoma. |
 | Media file 16: Upper GI barium series in a 56-year-old woman with NF1 shows multiple filling defects along the greater curve of the stomach due to neurofibromas. Note the multiple subcutaneous neurofibromas in the right upper quadrant. |
 | Media file 17: Upper GI barium series in a 56-year-old woman shows multiple polypoid filling defects throughout the small bowl due to neurofibromas (same patient as in Image 16). Note the subcutaneous neurofibromas projected over the right hypochondrium. |
More on Neurofibromatosis Type 1 |
| Overview: Neurofibromatosis Type 1 |
| Imaging: Neurofibromatosis Type 1 |
| Follow-up: Neurofibromatosis Type 1 |
 Multimedia: Neurofibromatosis Type 1 |
| References |
| « Previous Page |
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Further Reading
Keywords
NF, NF1, NF-1, von Recklinghausen disease, von Recklinghausen syndrome, von Recklinghausen's disease, von Recklinghausen's syndrome, elephant man, nerve sheath tumor, neurofibromas
