eMedicine Specialties > Radiology > Brain/Spine

Pineal Germinoma: Multimedia

Author: Chi-Shing Zee, MD, Chief of Neuroradiology, Professor, Departments of Radiology and Neurosurgery, University of Southern California School of Medicine
Coauthor(s): Paul Kim, MD, Assistant Professor of Radiology, USC School of Medicine; Vi Vu, MD, Clinical Instructor, USC School of Medicine
Contributor Information and Disclosures

Updated: Apr 18, 2007

Multimedia

Pineal germinoma in a 19-year-old man (same patie...Media file 1: Pineal germinoma in a 19-year-old man (same patient as in Images 2-4). Axial T1-weighted MRI shows an isointense lesion in the pineal region.
Pineal germinoma in a 19-year-old man (same patie...

Pineal germinoma in a 19-year-old man (same patient as in Images 2-4). Axial T1-weighted MRI shows an isointense lesion in the pineal region.

Pineal germinoma in a 19-year-old man (same patie...Media file 2: Pineal germinoma in a 19-year-old man (same patient as in Images 1, 3, and 4). Axial T2-weighted MRI shows an isointense mass in the pineal region.
Pineal germinoma in a 19-year-old man (same patie...

Pineal germinoma in a 19-year-old man (same patient as in Images 1, 3, and 4). Axial T2-weighted MRI shows an isointense mass in the pineal region.

Pineal germinoma in a 19-year-old man (same patie...Media file 3: Pineal germinoma in a 19-year-old man (same patient as in Images 1, 2, and 4). Axial T1-weighted contrast-enhanced MRI shows a homogeneously enhancing mass in the pineal region.
Pineal germinoma in a 19-year-old man (same patie...

Pineal germinoma in a 19-year-old man (same patient as in Images 1, 2, and 4). Axial T1-weighted contrast-enhanced MRI shows a homogeneously enhancing mass in the pineal region.

Pineal germinoma in a 19-year-old man (same patie...Media file 4: Pineal germinoma in a 19-year-old man (same patient as in Images 1-3). Sagittal T1-weighted contrast-enhanced MRI image demonstrates an enhancing mass in the pineal region. Compression of the quadrigeminal plate and aqueduct is shown.
Pineal germinoma in a 19-year-old man (same patie...

Pineal germinoma in a 19-year-old man (same patient as in Images 1-3). Sagittal T1-weighted contrast-enhanced MRI image demonstrates an enhancing mass in the pineal region. Compression of the quadrigeminal plate and aqueduct is shown.

Pineal germinoma in a 30-year-old man (same patie...Media file 5: Pineal germinoma in a 30-year-old man (same patient as in Images 6-10). Axial T2-weighted MRI shows a mildly hyperintense lesion involving the pineal region.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 6-10). Axial T2-weighted MRI shows a mildly hyperintense lesion involving the pineal region.

Pineal germinoma in a 30-year-old man (same patie...Media file 6: Pineal germinoma in a 30-year-old man (same patient as in Images 5, 7-10). Sagittal T1-weighted contrast-enhanced image demonstrates an enhancing mass in the pineal region.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 5, 7-10). Sagittal T1-weighted contrast-enhanced image demonstrates an enhancing mass in the pineal region.

Pineal germinoma in a 30-year-old man (same patie...Media file 7: Pineal germinoma in a 30-year-old man (same patient as in Images 5, 6, and 8-10). Axial T1-weighted contrast-enhanced image shows an enhancing mass in the pineal region with bilateral extension into the posterior thalami.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 5, 6, and 8-10). Axial T1-weighted contrast-enhanced image shows an enhancing mass in the pineal region with bilateral extension into the posterior thalami.

Pineal germinoma in a 30-year-old man (same patie...Media file 8: Pineal germinoma in a 30-year-old man (same patient as in Images 5-7, 9, and 10). After radiation treatment, axial T2-weighted MRI shows high signal intensity in the pineal region.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 5-7, 9, and 10). After radiation treatment, axial T2-weighted MRI shows high signal intensity in the pineal region.

Pineal germinoma in a 30-year-old man (same patie...Media file 9: Pineal germinoma in a 30-year-old man (same patient as in Images 5-8 and 10). After radiation treatment, axial T1-weighted contrast-enhanced MRI shows no enhancing tumor.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 5-8 and 10). After radiation treatment, axial T1-weighted contrast-enhanced MRI shows no enhancing tumor.

Pineal germinoma in a 30-year-old man (same patie...Media file 10: Pineal germinoma in a 30-year-old man (same patient as in Images 5-9). After radiation therapy, sagittal T1-weighted contrast-enhanced MRI demonstrates no abnormal enhancing tumor.
Pineal germinoma in a 30-year-old man (same patie...

Pineal germinoma in a 30-year-old man (same patient as in Images 5-9). After radiation therapy, sagittal T1-weighted contrast-enhanced MRI demonstrates no abnormal enhancing tumor.

More on Pineal Germinoma

Overview: Pineal Germinoma
Imaging: Pineal Germinoma
Multimedia: Pineal Germinoma
References

References

  1. Allen JC, Nisselbaum J, Epstein F, et al. Alphafetoprotein and human chorionic gonadotropin determination in cerebrospinal fluid. An aid to the diagnosis and management of intracranial germ-cell tumors. J Neurosurg. Sep 1979;51(3):368-74. [Medline].

  2. Chang CG, Kageyama N, Kobayashi T, et al. Pineal Tumors: clinical diagnosis, with special emphasis on the significance of pineal calcification. Neurosurgery. Jun 1981;8(6):656-68. [Medline].

  3. Edwards MS, Hudgins RJ, Wilson CB, et al. Pineal region tumors in children. J Neurosurg. May 1988;68(5):689-97. [Medline].

  4. Farng KT, Chang KP, Wong TT. Pediatric intracranial germinoma treated with chemotherapy alone. Chung Hua I Hsueh Tsa Chih (Taipei). Dec 1999;62(12):859-66. [Medline].

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  7. Jenkin D, Berry M, Chan H, et al. Pineal region germinomas in childhood treatment considerations. Int J Radiat Oncol Biol Phys. Mar 1990;18(3):541-5. [Medline].

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  10. Kluczewska E, Staniek-Sadowska J, Malecka-Tendera E. [Radiological evaluation of pineal pathology and its regions]. Neurol Neurochir Pol. Sep-Oct 1999;33(5):1129-38. [Medline].

  11. Koide O, Watanabe Y, Sato K. Pathological survey of intracranial germinoma and pinealoma in Japan. Cancer. Apr 15 1980;45(8):2119-30. [Medline].

  12. Lin SR, Crane MD, Lin ZS, et al. Characteristics of calcification in tumors of the pineal gland. Radiology. Mar 1978;126(3):721-6. [Medline].

  13. Moon WK, Chang KH, Han MH, Kim IO. Intracranial germinomas: correlation of imaging findings with tumor response to radiation therapy. AJR Am J Roentgenol. Mar 1999;172(3):713-6. [Medline].

  14. Rivarola, Belgorosky A, Mendilaharzu H. Precocious puberty in children with tumours of the suprasellar and pineal areas: organic central precocious puberty. Acta Paediatr. Jul 2001;90(7):751-6. [Medline].

  15. Smirniotopoulos JG, Rushing EJ, Mena H. Pineal region masses: differential diagnosis. Radiographics. May 1992;12(3):577-96. [Medline].

  16. Tamaki N, Yin D. Therapeutic strategies and surgical results for pineal region tumours. J Clin Neurosci. Mar 2000;7(2):125-8. [Medline].

  17. Teo HE, Tan AM. Clinics in diagnostic imaging (37). Germinoma of the pineal gland. Singapore Med J. May 1999;40(5):375-8. [Medline].

  18. Zee CS, Segall H, Apuzzo M, et al. MR imaging of pineal region neoplasms. J Comput Assist Tomogr. Jan-Feb 1991;15(1):56-63. [Medline].

  19. Zimmerman RA, Bilaniuk LT, Wood JH, et al. Computed tomography of pineal, parapineal, and histologically related tumors. Radiology. Dec 1980;137(3):669-77. [Medline].

  20. Zimmerman RA, Bilaniuk LT. Age-related incidence of pineal calcification detected by computed tomography. Radiology. Mar 1982;142(3):659-62. [Medline].

Further Reading

Keywords

pineal gland, pineal region neoplasms, germ cell tumors, pineal cell tumors, germinoma, mature teratoma, malignant teratoma, embryonal cell carcinoma, endodermal sinus tumor, choriocarcinoma, mixed germ cell tumor, parapineal masses, thalamic quadrigeminal plate and tectum, glioma, ependyma, ependymoma, velum interpositum and tentorium, meningioma, Parinaud syndrome

Contributor Information and Disclosures

Author

Chi-Shing Zee, MD, Chief of Neuroradiology, Professor, Departments of Radiology and Neurosurgery, University of Southern California School of Medicine
Chi-Shing Zee, MD is a member of the following medical societies: American Society of Neuroradiology
Disclosure: Nothing to disclose.

Coauthor(s)

Paul Kim, MD, Assistant Professor of Radiology, USC School of Medicine
Disclosure: Nothing to disclose.

Vi Vu, MD, Clinical Instructor, USC School of Medicine
Disclosure: Nothing to disclose.

Medical Editor

Pamela W Schaefer, MD, Assistant Professor of Radiology, Harvard Medical School; Associate Director of Neuroradiology, Clinical Director of Magnetic Resonance Imaging, Department of Radiology, Massachusetts General Hospital
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

James G Smirniotopoulos, MD, Professor of Radiology, Neurology, and Biomedical Informatics, Chairman, Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences
James G Smirniotopoulos, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, American Society of Head and Neck Radiology, American Society of Neuroradiology, American Society of Pediatric Neuroradiology, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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