eMedicine Specialties > Radiology > Brain/Spine

Progressive Multifocal Leukodystrophy: Follow-up

Author: Manohar Aribandi, MD, Academic Chief, Section of Neuroradiology, Department of Radiology, Geisinger Medical Center
Coauthor(s): Anil Kumar Aribandi, MBBS, MD, MRCP, Specialist Registrar, Department of Hematology, Manchester Royal Infirmary, UK
Contributor Information and Disclosures

Updated: Oct 14, 2009

Intervention

As of now, radiographically guided intervention has no role in the treatment of PML.

An antiretroviral regimen containing protease inhibitors has been successful in prolonging the survival of patients with HIV infection and PML. Topotecan and cidofovir are promising drugs presently under evaluation. The role of splenectomy remains unproven, though reports have described remission in association with HAART.

 


More on Progressive Multifocal Leukodystrophy

Overview: Progressive Multifocal Leukodystrophy
Imaging: Progressive Multifocal Leukodystrophy
Follow-up: Progressive Multifocal Leukodystrophy
Multimedia: Progressive Multifocal Leukodystrophy
References
Further Reading
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References

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Keywords

progressive multifocal leukodystrophy, PML, progressive multifocal leukoencephalopathy, acquired immune deficiency, AIDS, multifocal demyelination, JC virus,

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Contributor Information and Disclosures

Author

Manohar Aribandi, MD, Academic Chief, Section of Neuroradiology, Department of Radiology, Geisinger Medical Center
Manohar Aribandi, MD is a member of the following medical societies: American Society of Neuroradiology
Disclosure: Nothing to disclose.

Coauthor(s)

Anil Kumar Aribandi, MBBS, MD, MRCP, Specialist Registrar, Department of Hematology, Manchester Royal Infirmary, UK
Disclosure: Nothing to disclose.

Medical Editor

Mahesh R Patel, MD, Chief, MRI, Department of Diagnostic Imaging, Santa Clara Valley Medial Center
Mahesh R Patel, MD is a member of the following medical societies: American Roentgen Ray Society, American Society of Neuroradiology, and Radiological Society of North America
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Robert L DeLaPaz, MD, Director, Professor, Department of Radiology, Division of Neuroradiology, Columbia University
Robert L DeLaPaz, MD is a member of the following medical societies: American Society of Neuroradiology, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

L Gill Naul, MD, Professor and Head, Department of Radiology, Texas A&M University College of Medicine; Chair, Department of Radiology, Chief, Section of Magnetic Resonance Imaging, Scott and White Memorial Hospital and Clinic
L Gill Naul, MD is a member of the following medical societies: American College of Radiology, American Medical Association, American Roentgen Ray Society, Radiological Society of North America, and Texas Medical Association
Disclosure: Nothing to disclose.

 
 
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