eMedicine Specialties > Radiology > Brain/Spine

Toxoplasmosis, CNS: Multimedia

Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Coauthor(s): Ian Turnbull, MB, ChB, MD, DMRD, FRCR, Lecturer, Department of Radiology, University of Manchester; Consulting Neuroradiologist, Hope Hospital, Salford, Manchester and North Manchester General Hospital, UK; Riyadh Al-Okaili, MBBS, Interventional/Therapeutic and Diagnostic Neuro-Radiologist, King Abdulaziz Medical City; Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute
Contributor Information and Disclosures

Updated: Jun 7, 2007

Multimedia

Immunohistochemical or immunofluorescent techniqu...Media file 1: Immunohistochemical or immunofluorescent techniques can detect the Toxoplasma gondii parasite.
Immunohistochemical or immunofluorescent techniqu...

Immunohistochemical or immunofluorescent techniques can detect the Toxoplasma gondii parasite.

T1-weighted axial brain magnetic resonance image ...Media file 2: T1-weighted axial brain magnetic resonance image at the level of the basal ganglia in a 24-year-old man with human immunodeficiency virus infection. The image shows hypointense lesions in the region of the thalami (arrows) caused by toxoplasmosis.
T1-weighted axial brain magnetic resonance image ...

T1-weighted axial brain magnetic resonance image at the level of the basal ganglia in a 24-year-old man with human immunodeficiency virus infection. The image shows hypointense lesions in the region of the thalami (arrows) caused by toxoplasmosis.

T1-weighted axial brain magnetic resonance image ...Media file 3: T1-weighted axial brain magnetic resonance image at the level of the upper lateral ventricles in a 24-year-old man with human immunodeficiency virus infection (same patient as in Images 2, 4, and 5). The image shows a hypointense mass compressing the right lateral ventricle (arrow) .
T1-weighted axial brain magnetic resonance image ...

T1-weighted axial brain magnetic resonance image at the level of the upper lateral ventricles in a 24-year-old man with human immunodeficiency virus infection (same patient as in Images 2, 4, and 5). The image shows a hypointense mass compressing the right lateral ventricle (arrow) .

Transaxial contrast-enhanced computed tomography ...Media file 4: Transaxial contrast-enhanced computed tomography scan in a 24-year-old man with human immunodeficiency virus infection and central nervous system toxoplasmosis (same patient as in Images 2-3 and 5). This image was obtained after the patient received 20 days of treatment, with resultant clinical improvement, and shows a low-attenuating mass with minor peripheral ring enhancement. Note the reduction in the mass effect.
Transaxial contrast-enhanced computed tomography ...

Transaxial contrast-enhanced computed tomography scan in a 24-year-old man with human immunodeficiency virus infection and central nervous system toxoplasmosis (same patient as in Images 2-3 and 5). This image was obtained after the patient received 20 days of treatment, with resultant clinical improvement, and shows a low-attenuating mass with minor peripheral ring enhancement. Note the reduction in the mass effect.

T2-weighted coronal magnetic resonance image at t...Media file 5: T2-weighted coronal magnetic resonance image at the level of the insulae in a patient with human immunodeficiency virus infection and central nervous system toxoplasmosis (same patient as in Images 2-4). The image shows large, bilateral hyperintense lesions (almost symmetrically placed on either side of the third ventricle and/or lateral ventricle) (arrows). Note the slight mass effect on the right lateral ventricle (V).
T2-weighted coronal magnetic resonance image at t...

T2-weighted coronal magnetic resonance image at the level of the insulae in a patient with human immunodeficiency virus infection and central nervous system toxoplasmosis (same patient as in Images 2-4). The image shows large, bilateral hyperintense lesions (almost symmetrically placed on either side of the third ventricle and/or lateral ventricle) (arrows). Note the slight mass effect on the right lateral ventricle (V).

T1-weighted gadolinium-enhanced magnetic resonanc...Media file 6: T1-weighted gadolinium-enhanced magnetic resonance image at the level of the fourth ventricle in a 32-year-old patient with human immunodeficiency virus infection. The image shows a peripheral, right frontoparietal ring-enhancing lesion (arrows). The patient presented with a solitary space-occupying lesion, which was confirmed to be secondary to toxoplasmosis.
T1-weighted gadolinium-enhanced magnetic resonanc...

T1-weighted gadolinium-enhanced magnetic resonance image at the level of the fourth ventricle in a 32-year-old patient with human immunodeficiency virus infection. The image shows a peripheral, right frontoparietal ring-enhancing lesion (arrows). The patient presented with a solitary space-occupying lesion, which was confirmed to be secondary to toxoplasmosis.

T1-weighted axial gadolinium-enhanced magnetic re...Media file 7: T1-weighted axial gadolinium-enhanced magnetic resonance image at the level of the basal ganglia in a 37-year-old patient with human immunodeficiency virus infection. The image shows 2 complex, ring-enhancing lesions in the basal ganglia on the right, surrounded by notable white matter edema. Additional lesions were noted elsewhere in the brain. This appearance is typical of central nervous system toxoplasmosis, which has the propensity to involve the basal ganglia.
T1-weighted axial gadolinium-enhanced magnetic re...

T1-weighted axial gadolinium-enhanced magnetic resonance image at the level of the basal ganglia in a 37-year-old patient with human immunodeficiency virus infection. The image shows 2 complex, ring-enhancing lesions in the basal ganglia on the right, surrounded by notable white matter edema. Additional lesions were noted elsewhere in the brain. This appearance is typical of central nervous system toxoplasmosis, which has the propensity to involve the basal ganglia.

T1-weighted axial gadolinium-enhanced magnetic re...Media file 8: T1-weighted axial gadolinium-enhanced magnetic resonance images at 2 levels through the basal ganglia (same patient as in Image 7). These images show 2 complex, ring-enhancing lesions in the basal ganglia on the right, with surrounding notable white matter edema. This appearance is typical of central nervous system toxoplasmosis, which has the propensity for involvement of the basal ganglia.
T1-weighted axial gadolinium-enhanced magnetic re...

T1-weighted axial gadolinium-enhanced magnetic resonance images at 2 levels through the basal ganglia (same patient as in Image 7). These images show 2 complex, ring-enhancing lesions in the basal ganglia on the right, with surrounding notable white matter edema. This appearance is typical of central nervous system toxoplasmosis, which has the propensity for involvement of the basal ganglia.

Nonenhanced T1-weighted images in a patient infec...Media file 9: Nonenhanced T1-weighted images in a patient infected with human immunodeficiency virus and cerebral toxoplasmosis. These images show hypointense, asymmetrical, bilateral periventricular/basal ganglial lesions.
Nonenhanced T1-weighted images in a patient infec...

Nonenhanced T1-weighted images in a patient infected with human immunodeficiency virus and cerebral toxoplasmosis. These images show hypointense, asymmetrical, bilateral periventricular/basal ganglial lesions.

Axial fluid-attenuated, inversion recovery brain ...Media file 10: Axial fluid-attenuated, inversion recovery brain magnetic resonance image (same patient as in Image 9). These images show intense signal at the sites of the infection.
Axial fluid-attenuated, inversion recovery brain ...

Axial fluid-attenuated, inversion recovery brain magnetic resonance image (same patient as in Image 9). These images show intense signal at the sites of the infection.

More on Toxoplasmosis, CNS

Overview: Toxoplasmosis, CNS
Imaging: Toxoplasmosis, CNS
Multimedia: Toxoplasmosis, CNS
References

References

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Further Reading

Keywords

Toxoplasma gondii, T gondii, protozoal infection, parasitic infection, congenital toxoplasmosis, undercooked pork, undercooked lamb, raw meat, disseminated toxoplasmosis, acute toxoplasmosis, central nervous system toxoplasmosis, CNS toxoplasmosis, CNST

Contributor Information and Disclosures

Author

Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP is a member of the following medical societies: American Institute of Ultrasound in Medicine, Radiological Society of North America, Royal College of Physicians, Royal College of Physicians and Surgeons of the United States, Royal College of Radiologists, and Royal College of Surgeons of England
Disclosure: Nothing to disclose.

Coauthor(s)

Ian Turnbull, MB, ChB, MD, DMRD, FRCR, Lecturer, Department of Radiology, University of Manchester; Consulting Neuroradiologist, Hope Hospital, Salford, Manchester and North Manchester General Hospital, UK
Disclosure: Nothing to disclose.

Riyadh Al-Okaili, MBBS, Interventional/Therapeutic and Diagnostic Neuro-Radiologist, King Abdulaziz Medical City
Riyadh Al-Okaili, MBBS is a member of the following medical societies: American College of Radiology
Disclosure: Nothing to disclose.

Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute
Sumaira MacDonald, MBChB, PhD, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Medical Editor

Lucien M Levy, MD, PhD, Director of Neuroradiology, Professor of Radiology, Department of Radiology, George Washington University Medical Center
Lucien M Levy, MD, PhD is a member of the following medical societies: American Cancer Society, American College of Radiology, American Heart Association, American Medical Association, American Roentgen Ray Society, American Society of Neuroradiology, and Radiological Society of North America
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

C Douglas Phillips, MD, Professor, Departments of Radiology, Neurosurgery, and Otolaryngology, University of Virginia Health Sciences Center
C Douglas Phillips, MD is a member of the following medical societies: American College of Radiology, American Medical Association, American Society of Head and Neck Radiology, American Society of Neuroradiology, Association of University Radiologists, and Radiological Society of North America
Disclosure: Amirsys Royalty Consulting

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

James G Smirniotopoulos, MD, Professor of Radiology, Neurology, and Biomedical Informatics, Chairman, Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences
James G Smirniotopoulos, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, American Society of Head and Neck Radiology, American Society of Neuroradiology, American Society of Pediatric Neuroradiology, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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