Intervention
Fibroadenoma may be diagnosed by performing stereotactic core breast biopsy (if the mass is visible on mammography) or by performing ultrasound-guided biopsy (if the mass is visible on ultrasonograms). Ultrasound-guided cryotherapy has also been described as a successful, minimally invasive treatment for fibroadenomas.8,9
Cryoablation for breast fibroadenomas has been reported as a safe and effective treatment option to surgical excision.
Medicolegal Pitfalls
- A repeat biopsy should be performed if histologic findings are not concordant with image-guided biopsy findings. Repeat biopsy can be performed by means of either surgical excision or repeat image-guided biopsy.
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References
Prasad SN, Houserkova D, Campbell J. Breast imaging using 3D electrical impedence tomography. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. Jun 2008;152(1):151-4. [Medline].
Wurdinger S, Herzog AB, Fischer DR. Differentiation of phyllodes breast tumors from fibroadenomas on MRI. AJR Am J Roentgenol. Nov 2005;185(5):1317-21. [Full Text].
Hruska D, O'Brien WD, Oelze M. Mammary tumor classification using envelope statistics from ultrasound backscatter and the homodyned K distribution. J Acoust Soc Am. Apr 2009;125(4):2512. [Medline].
Park YM, Kim EK, Lee JH, Ryu JH, Han SS, Choi SJ, et al. Palpable breast masses with probably benign morphology at sonography: can biopsy be deferred?. Acta Radiol. Dec 2008;49(10):1104-11. [Medline].
Tsui PH, Yeh CK, Chang CC, Liao YY. Classification of breast masses by ultrasonic Nakagami imaging: a feasibility study. Phys Med Biol. Nov 7 2008;53(21):6027-44. [Medline].
Wenkel E, Heckmann M, Heinrich M, Schwab SA, Uder M, Schulz-Wendtland R, et al. Automated breast ultrasound: lesion detection and BI-RADS classification--a pilot study. Rofo. Sep 2008;180(9):804-8. [Medline].
Földi M, Klar M, Orlowska-Volk M, Hanjalic-Beck A, Osterloh B, Stickeler E, et al. Ultrasound Characteristics of Breast Fibroadenomas Are Related to Clinical and Histological Parameters. Ultraschall Med. Jun 18 2009;[Medline].
Kaufman CS, Littrup PJ, Freeman-Gibb LA. Office-based cryoablation of breast fibroadenomas with long-term follow-up. Breast J. Sep-Oct 2005;11(5):344-50. [Full Text].
Littrup PJ, Freeman-Gibb L, Andea A, et al. Cryotherapy for breast fibroadenomas. Radiology. Jan 2005;234(1):63-72. [Medline].
Acha T, Picazo B, Garcia-Martin FJ, et al. Carney''s triad: apropos of a new case. Med Pediatr Oncol. 1994;22(3):216-20. [Medline].
Alle KM, Moss J, Venegas RJ, et al. Conservative management of fibroadenoma of the breast. Br J Surg. Jul 1996;83(7):992-3. [Medline].
Courcoutsakis NA, Chow CK, Shawker TH, et al. Syndrome of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas (Carney complex): breast imaging findings. Radiology. Oct 1997;205(1):221-7. [Medline].
Dupont WD, Page DL, Parl FF. Long-term risk of breast cancer in women with fibroadenoma. N Engl J Med. Jul 7 1994;331(1):10-5. [Medline].
Frayne J, Sterrett GF, Harvey J. Stereotactic 14 gauge core-biopsy of the breast: results from 101 patients. Aust N Z J Surg. Sep 1996;66(9):585-91. [Medline].
Greenberg R, Skornick Y, Kaplan O. Management of breast fibroadenomas. J Gen Intern Med. Sep 1998;13(9):640-5. [Medline].
Kleer CG, Tseng MD, Gutsch DE, et al. Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts. Mod Pathol. Jul 2002;15(7):759-64. [Medline].
Kuhl CK. MRI of breast tumors. Eur Radiol. 2000;10(1):46-58. [Medline].
Markopoulos C, Kouskos E, Mantas D, et al. Fibroadenomas of the breast: is there any association with breast cancer?. Eur J Gynaecol Oncol. 2004;25(4):495-7. [Medline].
Further Reading
Related eMedicine topics
Fibroadenomatous Lesions of the Breast
Breast Abscess and Masses
Disorders of the Breast
Molecular Pathology of the Breast
Carney Syndrome
Clinical guidelines
Diagnosis of Breast Disease
Common Breast Problems
Clinical studies
American Breast Laser Ablation Therapy Evaluation (ABLATE)
Keywords
fibroadenoma of the breast, benign breast tumors, breast tumors, breast lesions, stromal tumors, myxomatous stroma, intralobular stroma, interlobular stroma, epithelial tumors, multiple fibroadenomas, complex fibroadenomas, breast hyperplasias, juvenile fibroadenomas, giant fibroadenomas
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