eMedicine Specialties > Radiology > Cardiac

Coronary Artery Disease: Multimedia

Author: Justin D Pearlman, MD, PhD, ME, MA, Director of Advanced Cardiovascular Imaging, Professor of Medicine, Professor of Radiology, Adjunct Professor, Thayer Bioengineering and Computer Science, Dartmouth-Hitchcock Medical Center
Contributor Information and Disclosures

Updated: Nov 3, 2009

Multimedia

Selective injection image of the left coronary ar...Media file 1: Selective injection image of the left coronary arteries. D1 = first diagonal, LAD = left anterior descending artery, LCX = left circumflex, LM = left main coronary artery, and OM1= first obtuse marginal.
Selective injection image of the left coronary ar...

Selective injection image of the left coronary arteries. D1 = first diagonal, LAD = left anterior descending artery, LCX = left circumflex, LM = left main coronary artery, and OM1= first obtuse marginal.

MRIs of the coronaries can be used to build 4-dim...Media file 2: MRIs of the coronaries can be used to build 4-dimensional images (3-dimensional beating heart). These images show a single frame, including a cutaway view to show the cardiac interior, the outer surface (no thresholding), and the extracted coronary artery tree including the aortic root.
MRIs of the coronaries can be used to build 4-dim...

MRIs of the coronaries can be used to build 4-dimensional images (3-dimensional beating heart). These images show a single frame, including a cutaway view to show the cardiac interior, the outer surface (no thresholding), and the extracted coronary artery tree including the aortic root.

Elastic-match imaging automatically identifies di...Media file 3: Elastic-match imaging automatically identifies differences between image volumes. The acquisition of 1 set of contrast-enhanced chest CT images via the coronaries and a nonenhanced set provides a 3-dimensional view of the coronary-artery tree. The nonenhanced volume data were rendered as holographic projections to provide the anatomic context, and the elastic-match coronary tree was overlaid. In addition to automation, this method avoids thresholding so that small branches and filling defects, if present, are represented properly.
Elastic-match imaging automatically identifies di...

Elastic-match imaging automatically identifies differences between image volumes. The acquisition of 1 set of contrast-enhanced chest CT images via the coronaries and a nonenhanced set provides a 3-dimensional view of the coronary-artery tree. The nonenhanced volume data were rendered as holographic projections to provide the anatomic context, and the elastic-match coronary tree was overlaid. In addition to automation, this method avoids thresholding so that small branches and filling defects, if present, are represented properly.

Elastic-match imaging can be used to identify col...Media file 4: Elastic-match imaging can be used to identify collateral-dependent myocardium. Left and middle images are baseline and peak-arrival collateral-sensitive MRIs demarcating microvascular development. Right image, based on CT imaging of the heart, was obtained with and without back pressure to nullify collateral-dependent perfusion; white volume on represents collateral-dependent myocardium. The extent of collateral-dependent myocardium corresponds well on MRI and CT (r = 0.95).
Elastic-match imaging can be used to identify col...

Elastic-match imaging can be used to identify collateral-dependent myocardium. Left and middle images are baseline and peak-arrival collateral-sensitive MRIs demarcating microvascular development. Right image, based on CT imaging of the heart, was obtained with and without back pressure to nullify collateral-dependent perfusion; white volume on represents collateral-dependent myocardium. The extent of collateral-dependent myocardium corresponds well on MRI and CT (r = 0.95).

Contrast-labeled blood to the heart is used to id...Media file 5: Contrast-labeled blood to the heart is used to identify the territory at risk. The results of this assessment of the delayed arrival compares favorably to the findings of radionuclide stress imaging, and stress induction of ischemia is not required to identify the zone at risk.
Contrast-labeled blood to the heart is used to id...

Contrast-labeled blood to the heart is used to identify the territory at risk. The results of this assessment of the delayed arrival compares favorably to the findings of radionuclide stress imaging, and stress induction of ischemia is not required to identify the zone at risk.

Space-time maps show the history of blood arrival...Media file 6: Space-time maps show the history of blood arrival to all layers of myocardium on a 2-dimensional map. The indentation indicates the severity of the defect in blood delivery, and the length indicates the size as a percentage of the myocardium, without the need for stress induction of ischemia. In addition to the safety advantage, this method is also more reproducible than stress testing, which is useful in assessing the effect of therapy.
Space-time maps show the history of blood arrival...

Space-time maps show the history of blood arrival to all layers of myocardium on a 2-dimensional map. The indentation indicates the severity of the defect in blood delivery, and the length indicates the size as a percentage of the myocardium, without the need for stress induction of ischemia. In addition to the safety advantage, this method is also more reproducible than stress testing, which is useful in assessing the effect of therapy.

Compared with radionuclide images of blood delive...Media file 7: Compared with radionuclide images of blood delivery, MRIs and CT scans improve resolution, depiction of the functional effect and the relationship to the coronary supply, and identification of the area at risk without stress. The advantage of radionuclide imaging is primarily its predictive value; stress echocardiography has similar predictive value. MRI and CT have been less available than other studies; therefore, data on their value are relatively limited.
Compared with radionuclide images of blood delive...

Compared with radionuclide images of blood delivery, MRIs and CT scans improve resolution, depiction of the functional effect and the relationship to the coronary supply, and identification of the area at risk without stress. The advantage of radionuclide imaging is primarily its predictive value; stress echocardiography has similar predictive value. MRI and CT have been less available than other studies; therefore, data on their value are relatively limited.

X-ray angiography is the criterion standard for d...Media file 8: X-ray angiography is the criterion standard for delineating the coronary anatomy, but it is inferior to MRI and CT in identifying myocardium with impaired blood delivery, in assessing the functional consequences, and in identifying the development of microvascular collaterals.
X-ray angiography is the criterion standard for d...

X-ray angiography is the criterion standard for delineating the coronary anatomy, but it is inferior to MRI and CT in identifying myocardium with impaired blood delivery, in assessing the functional consequences, and in identifying the development of microvascular collaterals.

More on Coronary Artery Disease

Overview: Coronary Artery Disease
Imaging: Coronary Artery Disease
Follow-up: Coronary Artery Disease
Multimedia: Coronary Artery Disease
References
Further Reading

References

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Keywords

coronary artery disease, CAD, heart disease, coronary angiography, coronary angioscopy, coronary artery imaging, magnetic resonance angiography, MRA, stress test, perfusion imaging, collateral-sensitive imaging, heart attack, myocardial infarction, MI, acute myocardial infarction, AMI, angina, UA, unstable angina, stent, DES, drug-eluting stent

Contributor Information and Disclosures

Author

Justin D Pearlman, MD, PhD, ME, MA, Director of Advanced Cardiovascular Imaging, Professor of Medicine, Professor of Radiology, Adjunct Professor, Thayer Bioengineering and Computer Science, Dartmouth-Hitchcock Medical Center
Justin D Pearlman, MD, PhD, ME, MA is a member of the following medical societies: American College of Cardiology, American College of Physicians, American Federation for Medical Research, International Society for Magnetic Resonance in Medicine, and Radiological Society of North America
Disclosure: Nothing to disclose.

Medical Editor

Justin D Pearlman, MD, PhD, ME, MA, Director of Advanced Cardiovascular Imaging, Professor of Medicine, Professor of Radiology, Adjunct Professor, Thayer Bioengineering and Computer Science, Dartmouth-Hitchcock Medical Center
Justin D Pearlman, MD, PhD, ME, MA is a member of the following medical societies: American College of Cardiology, American College of Physicians, American Federation for Medical Research, International Society for Magnetic Resonance in Medicine, and Radiological Society of North America
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

John D Newell Jr, MD, Professor of Radiology, Co-Director of Thoracic Imaging, Department of Radiology, University of Colorado Health Sciences Center; Professor of Medicine, Medical Director of Lung Imaging Center, National Jewish Medical and Research Center
John D Newell Jr, MD is a member of the following medical societies: American College of Chest Physicians, American College of Radiology, American Roentgen Ray Society, American Thoracic Society, Association of University Radiologists, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Siemens Medical Grant/research funds Consulting; Forevision Technologies Ownership interest Consulting; Vida Corporation Ownership interest Board membership; TeraRecon Grant/research funds Consulting; eMedicine Honoraria Consulting

CME Editor

Robert M Krasny, MD, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Consulting Radiologist, Virginia Mason Medical Center; Clinical Assistant Professor of Radiology, University of Washington School of Medicine
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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