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Aspergillosis, Thoracic: Multimedia

Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Coauthor(s): Sarah Al Ghanem, MBBS, Consulting Staff, Department of Medical Imaging, King Fahad National Guard Hospital, Riyadh, Saudi Arabia; Klaus L Irion, MD, PhD, Consulting Staff, The Cardiothoracic Centre Liverpool NHS Trust, The Royal Liverpool University Hospital, UK; Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute; Carolyn M Allen, MB, BCh, MRCP, FRCR, CCST, Consultant Radiologist, Department of Clinical Radiology, North Manchester General Hospital, UK
Contributor Information and Disclosures

Updated: May 1, 2008

Multimedia

Microscopic slide of lung tissue. This image show...Media file 1: Microscopic slide of lung tissue. This image shows broad hyphae, which branch at acute angles.
Microscopic slide of lung tissue. This image show...

Microscopic slide of lung tissue. This image shows broad hyphae, which branch at acute angles.

Section of a blood vessel. This image shows branc...Media file 2: Section of a blood vessel. This image shows branching fungal hyphae that invade the vessel wall.
Section of a blood vessel. This image shows branc...

Section of a blood vessel. This image shows branching fungal hyphae that invade the vessel wall.

Posteroanterior chest radiograph in a patient wit...Media file 3: Posteroanterior chest radiograph in a patient with allergic bronchopulmonary aspergillosis. This image shows branching finger-in-glove tubular opacities in the left lower lobe (ie, retrocardiac location) due to mucus plugging of ectatic bronchi.
Posteroanterior chest radiograph in a patient wit...

Posteroanterior chest radiograph in a patient with allergic bronchopulmonary aspergillosis. This image shows branching finger-in-glove tubular opacities in the left lower lobe (ie, retrocardiac location) due to mucus plugging of ectatic bronchi.

High-resolution computed tomography scan (same pa...Media file 4: High-resolution computed tomography scan (same patient as in Image 3). This image shows peribronchial thickening and apparent nodular opacities in the lower lobes due to bronchiectasis with mucoid impaction.
High-resolution computed tomography scan (same pa...

High-resolution computed tomography scan (same patient as in Image 3). This image shows peribronchial thickening and apparent nodular opacities in the lower lobes due to bronchiectasis with mucoid impaction.

High-resolution computed tomography scan shows ce...Media file 5: High-resolution computed tomography scan shows central bronchiectasis in a patient with allergic bronchopulmonary aspergillosis. The patient had previously undergone left upper lobectomy for severe bronchiectasis.
High-resolution computed tomography scan shows ce...

High-resolution computed tomography scan shows central bronchiectasis in a patient with allergic bronchopulmonary aspergillosis. The patient had previously undergone left upper lobectomy for severe bronchiectasis.

Posteroanterior chest radiograph shows multiple a...Media file 6: Posteroanterior chest radiograph shows multiple aspergillomas in a patient with tuberculosis. Note the numerous air crescents.
Posteroanterior chest radiograph shows multiple a...

Posteroanterior chest radiograph shows multiple aspergillomas in a patient with tuberculosis. Note the numerous air crescents.

Posteroanterior chest radiograph shows chronic, c...Media file 7: Posteroanterior chest radiograph shows chronic, cavitating, upper lobe consolidation in a patient with long-standing fibrosing alveolitis; this finding is consistent with chronic necrotizing aspergillosis. Aspergillus fumigatus was cultured from the sputum and percutaneous aspiration samples.
Posteroanterior chest radiograph shows chronic, c...

Posteroanterior chest radiograph shows chronic, cavitating, upper lobe consolidation in a patient with long-standing fibrosing alveolitis; this finding is consistent with chronic necrotizing aspergillosis. Aspergillus fumigatus was cultured from the sputum and percutaneous aspiration samples.

Axial computed tomography scan obtained at the le...Media file 8: Axial computed tomography scan obtained at the level of the aortic arch (same patient as in Image 7). This image shows a masslike consolidation, with a developing air crescent adjacent to the central sequestrated lung, which mimics a mycetoma.
Axial computed tomography scan obtained at the le...

Axial computed tomography scan obtained at the level of the aortic arch (same patient as in Image 7). This image shows a masslike consolidation, with a developing air crescent adjacent to the central sequestrated lung, which mimics a mycetoma.

Axial nonenhanced computed tomography scan obtain...Media file 9: Axial nonenhanced computed tomography scan obtained through the lower thorax. This image shows a subtle left lower lobe nodule due to invasive aspergillosis in a renal transplant recipient. The patient had multiple other nodules, one of which was examined at biopsy to confirm the diagnosis. Note the esophagus has thickened walls secondary to concurrent cytomegaloviral infection.
Axial nonenhanced computed tomography scan obtain...

Axial nonenhanced computed tomography scan obtained through the lower thorax. This image shows a subtle left lower lobe nodule due to invasive aspergillosis in a renal transplant recipient. The patient had multiple other nodules, one of which was examined at biopsy to confirm the diagnosis. Note the esophagus has thickened walls secondary to concurrent cytomegaloviral infection.

Posteroanterior chest radiograph shows a left upp...Media file 10: Posteroanterior chest radiograph shows a left upper lobe mycetoma with an indwelling catheter for drug delivery.
Posteroanterior chest radiograph shows a left upp...

Posteroanterior chest radiograph shows a left upper lobe mycetoma with an indwelling catheter for drug delivery.

Flush thoracic aortogram obtained in a patient wi...Media file 11: Flush thoracic aortogram obtained in a patient with a mycetoma and hemoptysis. This image shows anastomosis involving the bronchial artery, intercostal arteries, and pulmonary artery. Note also the anastomosis with blood vessels from the lateral thoracic wall.
Flush thoracic aortogram obtained in a patient wi...

Flush thoracic aortogram obtained in a patient with a mycetoma and hemoptysis. This image shows anastomosis involving the bronchial artery, intercostal arteries, and pulmonary artery. Note also the anastomosis with blood vessels from the lateral thoracic wall.

Right bronchial angiogram in a 40-year old man wi...Media file 12: Right bronchial angiogram in a 40-year old man with a known right lung mycetoma (arrow). This image shows extensive anastomosis between the right bronchial artery and the intercostal arteries.
Right bronchial angiogram in a 40-year old man wi...

Right bronchial angiogram in a 40-year old man with a known right lung mycetoma (arrow). This image shows extensive anastomosis between the right bronchial artery and the intercostal arteries.

This posteroanterior chest radiograph was obtaine...Media file 13: This posteroanterior chest radiograph was obtained in a 36-year-old woman who was previously treated for pulmonary tuberculosis (same patient in Images 13-18). The patient had a left upper lobe mycetoma and presented with recurrent life-threatening hemoptysis. The disease failed to respond to systemic and local antifungal therapy.
This posteroanterior chest radiograph was obtaine...

This posteroanterior chest radiograph was obtained in a 36-year-old woman who was previously treated for pulmonary tuberculosis (same patient in Images 13-18). The patient had a left upper lobe mycetoma and presented with recurrent life-threatening hemoptysis. The disease failed to respond to systemic and local antifungal therapy.

Angiogram of the left thyrocervical trunk in a 36...Media file 14: Angiogram of the left thyrocervical trunk in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows that the blood supply to the mycetoma is derived from the thyrocervical trunk.
Angiogram of the left thyrocervical trunk in a 36...

Angiogram of the left thyrocervical trunk in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows that the blood supply to the mycetoma is derived from the thyrocervical trunk.

Delayed-phase angiogram in a 36-year-old woman wi...Media file 15: Delayed-phase angiogram in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows anastomosis of the branches of the thyrocervical trunk with the left pulmonary artery at the site of the mycetoma.
Delayed-phase angiogram in a 36-year-old woman wi...

Delayed-phase angiogram in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows anastomosis of the branches of the thyrocervical trunk with the left pulmonary artery at the site of the mycetoma.

Angiographic series of the thyrocervical trunk in...Media file 16: Angiographic series of the thyrocervical trunk in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image was obtained after embolization and shows a pruned-tree appearance of the arterial trunks. Note that the left internal mammary artery had to be sacrificed.
Angiographic series of the thyrocervical trunk in...

Angiographic series of the thyrocervical trunk in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image was obtained after embolization and shows a pruned-tree appearance of the arterial trunks. Note that the left internal mammary artery had to be sacrificed.

Angiogram of the right fifth intercostal artery i...Media file 17: Angiogram of the right fifth intercostal artery in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows that the artery meanders around to the left hemithorax and supplies the left-sided mycetoma.
Angiogram of the right fifth intercostal artery i...

Angiogram of the right fifth intercostal artery in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows that the artery meanders around to the left hemithorax and supplies the left-sided mycetoma.

Angiogram of the right 5th intercostal artery in ...Media file 18: Angiogram of the right 5th intercostal artery in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows the blind stump of the artery after embolization. When this article was written, the patient was alive and well and had had no further episodes of hemoptysis for more than 3 years.
Angiogram of the right 5th intercostal artery in ...

Angiogram of the right 5th intercostal artery in a 36-year-old woman with a left upper lobe mycetoma and a past history of being treated for pulmonary tuberculosis (same patient in Images 13-18). This image shows the blind stump of the artery after embolization. When this article was written, the patient was alive and well and had had no further episodes of hemoptysis for more than 3 years.

More on Aspergillosis, Thoracic

Overview: Aspergillosis, Thoracic
Imaging: Aspergillosis, Thoracic
Follow-up: Aspergillosis, Thoracic
Multimedia: Aspergillosis, Thoracic
References

References

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Further Reading

Keywords

pulmonary aspergillosis, Aspergillus fumigatus, A fumigatus, allergic bronchopulmonary aspergillosis, ABPA, saprophytic aspergillosis, aspergilloma, chronic necrotizing aspergillosis, airway-invasive aspergillosis, semi-invasive aspergillosis, angioinvasive aspergillosis, finger-in-glove sign, tree-in-bud sign, air-crescent sign

Contributor Information and Disclosures

Author

Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP is a member of the following medical societies: American Institute of Ultrasound in Medicine, Radiological Society of North America, Royal College of Physicians, Royal College of Physicians and Surgeons of the United States, Royal College of Radiologists, and Royal College of Surgeons of England
Disclosure: Nothing to disclose.

Coauthor(s)

Sarah Al Ghanem, MBBS, Consulting Staff, Department of Medical Imaging, King Fahad National Guard Hospital, Riyadh, Saudi Arabia
Disclosure: Nothing to disclose.

Klaus L Irion, MD, PhD, Consulting Staff, The Cardiothoracic Centre Liverpool NHS Trust, The Royal Liverpool University Hospital, UK
Klaus L Irion, MD, PhD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute
Sumaira MacDonald, MBChB, PhD, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Carolyn M Allen, MB, BCh, MRCP, FRCR, CCST, Consultant Radiologist, Department of Clinical Radiology, North Manchester General Hospital, UK
Carolyn M Allen, MB, BCh, MRCP, FRCR, CCST is a member of the following medical societies: Society of Thoracic Radiology
Disclosure: Nothing to disclose.

Medical Editor

Satinder P Singh, MD, Associate Professor of Radiology, Chief of Cardiopulmonary Radiology, Director of Cardiac CT, Director of Combined Cardiopulmonary and Abdominal Radiology, Department of Radiology, University of Alabama at Birmingham
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Eric J Stern, MD, Professor of Radiology, Adjunct Professor of Medicine, Adjunct Professor of Medical Education and Biomedical Informatics, University of Washington School of Medicine; Director of Thoracic Imaging, Harborview Medical Center; Associate Medical Staff, Seattle Cancer Care Alliance
Eric J Stern, MD is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, European Society of Radiology, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Barry H Gross, MD, Professor, Department of Radiology, University of Michigan Medical School; Professor, University of Michigan Cancer Center
Barry H Gross, MD is a member of the following medical societies: American College of Chest Physicians, American College of Radiology, American Roentgen Ray Society, Association of University Radiologists, Michigan State Medical Society, Physicians for Social Responsibility, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Nothing to disclose.

 
 
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