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Blastomycosis, Thoracic: Multimedia

Author: Fahad M Alhameed, MD, AmBIM, FCCP, FRCPC, Deputy Chairman of Intensive Care Department, Consultant Critical Care and Pulmonary Medicine, Department of Intensive Care and Pulmonary Medicine, King Khalid National Guard Hospital, Jeddah, Saudi Arabia
Coauthor(s): Sat Sharma, MD, FRCPC, Professor and Head, Division of Pulmonary Medicine, Department of Internal Medicine, University of Manitoba; Site Director, Respiratory Medicine, St. Boniface General Hospital; Bruce Maycher, MD, Director of Pulmonary Radiology, St Boniface General Hospital; Associate Professor, Department of Radiology, University of Manitoba
Contributor Information and Disclosures

Updated: Oct 17, 2008

Multimedia

A patient visited central Canada several months a...Media file 1: A patient visited central Canada several months ago. He developed cough, fever, and dyspnea. Chest radiograph demonstrates focal patchy opacity in the lingula. Blastomyces dermatitidis was identified on bronchoscopy.
A patient visited central Canada several months a...

A patient visited central Canada several months ago. He developed cough, fever, and dyspnea. Chest radiograph demonstrates focal patchy opacity in the lingula. Blastomyces dermatitidis was identified on bronchoscopy.

Lateral chest radiograph (same patient as in Ima...Media file 2: Lateral chest radiograph (same patient as in Image 1) reveals the ill-defined lingular opacity and an absence of pleural effusions.
Lateral chest radiograph (same patient as in Ima...

Lateral chest radiograph (same patient as in Image 1) reveals the ill-defined lingular opacity and an absence of pleural effusions.

A patient on mechanical ventilation because of ac...Media file 3: A patient on mechanical ventilation because of acute respiratory distress secondary to diffuse blastomycosis. Bilateral pneumothoraces are the result of barotrauma. Right chest wall subcutaneous emphysema resulted from chest tube placement.
A patient on mechanical ventilation because of ac...

A patient on mechanical ventilation because of acute respiratory distress secondary to diffuse blastomycosis. Bilateral pneumothoraces are the result of barotrauma. Right chest wall subcutaneous emphysema resulted from chest tube placement.

Chest CT image reveals patchy, dense lung opacifi...Media file 4: Chest CT image reveals patchy, dense lung opacification in the right middle and lower lobes. This is the most common presentation of blastomycosis. Lung opacities may be patchy or confluent and subsegmental or nonsegmental.
Chest CT image reveals patchy, dense lung opacifi...

Chest CT image reveals patchy, dense lung opacification in the right middle and lower lobes. This is the most common presentation of blastomycosis. Lung opacities may be patchy or confluent and subsegmental or nonsegmental.

Chest radiograph demonstrates a spiculated mass o...Media file 5: Chest radiograph demonstrates a spiculated mass overlying the left hilum. This radiographic finding mimics that of bronchogenic carcinoma; thus, a biopsy is needed for tissue diagnosis.
Chest radiograph demonstrates a spiculated mass o...

Chest radiograph demonstrates a spiculated mass overlying the left hilum. This radiographic finding mimics that of bronchogenic carcinoma; thus, a biopsy is needed for tissue diagnosis.

Lateral chest radiograph (same patient as in Imag...Media file 6: Lateral chest radiograph (same patient as in Image 5) reveals the central mass overlying the left hilum.
Lateral chest radiograph (same patient as in Imag...

Lateral chest radiograph (same patient as in Image 5) reveals the central mass overlying the left hilum.

Chest radiograph from a patient with pulmonary bl...Media file 7: Chest radiograph from a patient with pulmonary blastomycosis demonstrates multiple nodular lesions, some of which are cavitating, in the left lower lobe. Cavitation occurs in 15-20% of patients with blastomycosis.
Chest radiograph from a patient with pulmonary bl...

Chest radiograph from a patient with pulmonary blastomycosis demonstrates multiple nodular lesions, some of which are cavitating, in the left lower lobe. Cavitation occurs in 15-20% of patients with blastomycosis.

Chest CT (same patient as in Image 7) reveals a t...Media file 8: Chest CT (same patient as in Image 7) reveals a thick wall cavity in the left lower lobe with surrounding focal parenchymal disease; needle biopsy of this lesion confirmed blastomycosis. Cavitation occurs in 15-20% of patients with blastomycosis.
Chest CT (same patient as in Image 7) reveals a t...

Chest CT (same patient as in Image 7) reveals a thick wall cavity in the left lower lobe with surrounding focal parenchymal disease; needle biopsy of this lesion confirmed blastomycosis. Cavitation occurs in 15-20% of patients with blastomycosis.

Chest radiograph from a patient with disseminated...Media file 9: Chest radiograph from a patient with disseminated blastomycosis demonstrates diffuse miliary infiltrates associated with respiratory failure that required mechanical ventilation. In this patient, dense opacification with cavitation is seen in the right upper lobe. In a minority of patients, a diffuse micronodular pattern is seen; such a pattern results from hematogenous spread of the disease.
Chest radiograph from a patient with disseminated...

Chest radiograph from a patient with disseminated blastomycosis demonstrates diffuse miliary infiltrates associated with respiratory failure that required mechanical ventilation. In this patient, dense opacification with cavitation is seen in the right upper lobe. In a minority of patients, a diffuse micronodular pattern is seen; such a pattern results from hematogenous spread of the disease.

Chest radiograph from a patient with blastomycosi...Media file 10: Chest radiograph from a patient with blastomycosis reveals left hilar lymphadenopathy, an uncommon finding in patients with blastomycosis.
Chest radiograph from a patient with blastomycosi...

Chest radiograph from a patient with blastomycosis reveals left hilar lymphadenopathy, an uncommon finding in patients with blastomycosis.

More on Blastomycosis, Thoracic

Overview: Blastomycosis, Thoracic
Imaging: Blastomycosis, Thoracic
Follow-up: Blastomycosis, Thoracic
Multimedia: Blastomycosis, Thoracic
References
Further Reading

References

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  7. Wisconsin Department of Health Services. RARE FUNGAL INFECTION CAN GO UNDIAGNOSED. Last revised Sept. 12, 2008. Wisconsin Department of Health Services. Available at http://dhs.wisconsin.gov/News/PressReleases/2008/091208Blasto.htm. Accessed October 17, 2008.

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Further Reading

Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America.
Infectious Diseases Society of America.  2000 Apr (revised 2008 Jun 15).  12 pages.  NGC:006497

Coccidioidomycosis.
Infectious Diseases Society of America.  2000 Apr (revised 2005 Nov 1).  7 pages.  NGC:004563 

Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America.
Infectious Diseases Society of America.  2000 Apr (revised 2007 Oct).  19 pages.  NGC:005950 
 

Keywords

blastomycosis, thoracic blastomycosis, Blastomyces dermatitidis, pulmonary blastomycosis, disseminated blastomycosis, blastomycetoma, blastocytoma, Gilchrist disease, mycosis, mycoses

Contributor Information and Disclosures

Author

Fahad M Alhameed, MD, AmBIM, FCCP, FRCPC, Deputy Chairman of Intensive Care Department, Consultant Critical Care and Pulmonary Medicine, Department of Intensive Care and Pulmonary Medicine, King Khalid National Guard Hospital, Jeddah, Saudi Arabia
Fahad M Alhameed, MD, AmBIM, FCCP, FRCPC is a member of the following medical societies: American College of Chest Physicians, American Thoracic Society, Canadian Medical Association, and Royal College of Physicians and Surgeons of Canada
Disclosure: Nothing to disclose.

Coauthor(s)

Sat Sharma, MD, FRCPC, Professor and Head, Division of Pulmonary Medicine, Department of Internal Medicine, University of Manitoba; Site Director, Respiratory Medicine, St. Boniface General Hospital
Sat Sharma, MD, FRCPC is a member of the following medical societies: American Academy of Sleep Medicine, American College of Chest Physicians, American College of Physicians-American Society of Internal Medicine, American Thoracic Society, Canadian Medical Association, Royal College of Physicians and Surgeons of Canada, Royal Society of Medicine, Society of Critical Care Medicine, and World Medical Association
Disclosure: Nothing to disclose.

Bruce Maycher, MD, Director of Pulmonary Radiology, St Boniface General Hospital; Associate Professor, Department of Radiology, University of Manitoba
Bruce Maycher, MD is a member of the following medical societies: American Roentgen Ray Society, Canadian Medical Association, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Nothing to disclose.

Medical Editor

Satinder P Singh, MD, Associate Professor of Radiology, Chief of Cardiopulmonary Radiology, Director of Cardiac CT, Director of Combined Cardiopulmonary and Abdominal Radiology, Department of Radiology, University of Alabama at Birmingham
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Eric J Stern, MD, Professor of Radiology, Adjunct Professor of Medicine, Adjunct Professor of Medical Education and Biomedical Informatics, University of Washington School of Medicine; Director of Thoracic Imaging, Harborview Medical Center; Associate Medical Staff, Seattle Cancer Care Alliance
Eric J Stern, MD is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, European Society of Radiology, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Clinical Assistant Professor of Radiology, University of Washington Medical School
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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