eMedicine Specialties > Radiology > Chest

Mediastinum, Germ Cell Tumors: Multimedia

Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, Consultant Radiologist, North Manchester General Hospital, The Pennine Acute NHS Trust, Manchester UK
Coauthor(s): Klaus L Irion, MD, PhD, Consulting Staff, The Cardiothoracic Centre Liverpool NHS Trust, The Royal Liverpool University Hospital, UK; Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute; Nigel Thomas, MBBS, Vice-Chair, Manchester (North) Research Ethics Committee; Honorary Lecturer, Visiting Professor, University of Salford, UK
Contributor Information and Disclosures

Updated: Jul 25, 2008

Multimedia

Smooth, well-defined anterior mediastinal tumor w...Media file 1: Smooth, well-defined anterior mediastinal tumor with heterogeneous attenuation associated with calcific intratumoral nodules suggests a mediastinal teratodermoid. Note also the curvilinear calcification.
Smooth, well-defined anterior mediastinal tumor w...

Smooth, well-defined anterior mediastinal tumor with heterogeneous attenuation associated with calcific intratumoral nodules suggests a mediastinal teratodermoid. Note also the curvilinear calcification.

Coned view of the superior mediastinum shows a we...Media file 2: Coned view of the superior mediastinum shows a well-defined anterior mediastinal tumor with calcific intratumoral nodules suggestive of a mediastinal teratodermoid. Note also the curvilinear calcification
Coned view of the superior mediastinum shows a we...

Coned view of the superior mediastinum shows a well-defined anterior mediastinal tumor with calcific intratumoral nodules suggestive of a mediastinal teratodermoid. Note also the curvilinear calcification

Patient with asymmetrically placed anterior media...Media file 3: Patient with asymmetrically placed anterior mediastinal mass. Lateral linear tomogram shows a well-defined, uniformly attenuating mass (not shown), sonogram shows a mass with smooth, uniform echotexture. The patient had not undergone surgery, and findings on follow-up over several years showed little change.
Patient with asymmetrically placed anterior media...

Patient with asymmetrically placed anterior mediastinal mass. Lateral linear tomogram shows a well-defined, uniformly attenuating mass (not shown), sonogram shows a mass with smooth, uniform echotexture. The patient had not undergone surgery, and findings on follow-up over several years showed little change.

Contrast-enhanced axial CT scan shows an ill-defi...Media file 4: Contrast-enhanced axial CT scan shows an ill-defined anterior mediastinal mass with irregular borders that is infiltrating the mediastinal fat. CT-guided needle biopsy revealed a mediastinal seminoma.
Contrast-enhanced axial CT scan shows an ill-defi...

Contrast-enhanced axial CT scan shows an ill-defined anterior mediastinal mass with irregular borders that is infiltrating the mediastinal fat. CT-guided needle biopsy revealed a mediastinal seminoma.

Smooth, well-defined anterior mediastinal tumor w...Media file 5: Smooth, well-defined anterior mediastinal tumor with uniform attenuation. At surgery, a mediastinal dermoid was diagnosed. Note the hilum-overlay sign, suggestive of an anterior or posterior mediastinal mass. See also Images 6-7 in Multimedia.
Smooth, well-defined anterior mediastinal tumor w...

Smooth, well-defined anterior mediastinal tumor with uniform attenuation. At surgery, a mediastinal dermoid was diagnosed. Note the hilum-overlay sign, suggestive of an anterior or posterior mediastinal mass. See also Images 6-7 in Multimedia.

Lateral conventional tomogram in the same patient...Media file 6: Lateral conventional tomogram in the same patient as in Image 4 shows a smooth, well-defined, uniformly attenuating anterior mediastinal mass with no calcification.
Lateral conventional tomogram in the same patient...

Lateral conventional tomogram in the same patient as in Image 4 shows a smooth, well-defined, uniformly attenuating anterior mediastinal mass with no calcification.

Mediastinal sonogram obtained through the right p...Media file 7: Mediastinal sonogram obtained through the right parasternal area of an anterior intercostal space shows a mass of uniform echogenicity with posterior acoustic enhancement in the same patient as in Images 5-6 in Multimedia.
Mediastinal sonogram obtained through the right p...

Mediastinal sonogram obtained through the right parasternal area of an anterior intercostal space shows a mass of uniform echogenicity with posterior acoustic enhancement in the same patient as in Images 5-6 in Multimedia.

Lobulated but smooth and well-defined superior me...Media file 8: Lobulated but smooth and well-defined superior mediastinal mass with uniform attenuation. See also Image 9 in Multimedia.
Lobulated but smooth and well-defined superior me...

Lobulated but smooth and well-defined superior mediastinal mass with uniform attenuation. See also Image 9 in Multimedia.

Mediastinal sonogram obtained through the suprast...Media file 9: Mediastinal sonogram obtained through the suprasternal notch in the same patient as in Image 11 shows an ill-defined tumor with a heterogeneous echo pattern. At surgery, a teratodermoid was diagnosed. The mass contained small foci of calcification.
Mediastinal sonogram obtained through the suprast...

Mediastinal sonogram obtained through the suprasternal notch in the same patient as in Image 11 shows an ill-defined tumor with a heterogeneous echo pattern. At surgery, a teratodermoid was diagnosed. The mass contained small foci of calcification.

Another patient with a biopsy proven anterior med...Media file 10: Another patient with a biopsy proven anterior mediastinal dermoid extending across both sides of the midline.
Another patient with a biopsy proven anterior med...

Another patient with a biopsy proven anterior mediastinal dermoid extending across both sides of the midline.

Differential diagnosis. Contrast-enhanced CT thro...Media file 11: Differential diagnosis. Contrast-enhanced CT through the anterior mediastinum shows a minimally enhancing anterior mediastinal mass. At surgery, a malignant thymoma was diagnosed.
Differential diagnosis. Contrast-enhanced CT thro...

Differential diagnosis. Contrast-enhanced CT through the anterior mediastinum shows a minimally enhancing anterior mediastinal mass. At surgery, a malignant thymoma was diagnosed.

Contrast-enhanced CT through the anterior mediast...Media file 12: Contrast-enhanced CT through the anterior mediastinum shows a minimally enhancing anterior mediastinal mass. At surgery, a malignant thymoma was diagnosed (see also Image 11 in Multimedia).
Contrast-enhanced CT through the anterior mediast...

Contrast-enhanced CT through the anterior mediastinum shows a minimally enhancing anterior mediastinal mass. At surgery, a malignant thymoma was diagnosed (see also Image 11 in Multimedia).

Differential diagnosis. Mediastinal widening in a...Media file 13: Differential diagnosis. Mediastinal widening in a child with acute lymphatic leukemia caused by mediastinal lymphadenopathy.
Differential diagnosis. Mediastinal widening in a...

Differential diagnosis. Mediastinal widening in a child with acute lymphatic leukemia caused by mediastinal lymphadenopathy.

Differential diagnosis. Chest radiograph shows ex...Media file 14: Differential diagnosis. Chest radiograph shows extensive mediastinal lymphadenopathy due to non-Hodgkin lymphoma.
Differential diagnosis. Chest radiograph shows ex...

Differential diagnosis. Chest radiograph shows extensive mediastinal lymphadenopathy due to non-Hodgkin lymphoma.

Differential diagnosis. Posteroanterior chest rad...Media file 15: Differential diagnosis. Posteroanterior chest radiograph shows a mass in continuation with the aortic knuckle. Findings on contrast-enhanced CT confirmed that the mass was an aortic aneurysm (not shown).
Differential diagnosis. Posteroanterior chest rad...

Differential diagnosis. Posteroanterior chest radiograph shows a mass in continuation with the aortic knuckle. Findings on contrast-enhanced CT confirmed that the mass was an aortic aneurysm (not shown).

Contrast-enhanced CT scan obtained through the me...Media file 16: Contrast-enhanced CT scan obtained through the mediastinum in 56-year-old man shows an infiltrative enhancing tumor. Note the pleural effusion. Biopsy confirmed a sarcomatous-type germ cell tumor.
Contrast-enhanced CT scan obtained through the me...

Contrast-enhanced CT scan obtained through the mediastinum in 56-year-old man shows an infiltrative enhancing tumor. Note the pleural effusion. Biopsy confirmed a sarcomatous-type germ cell tumor.

Posteroanterior chest radiograph and nonenhanced ...Media file 17: Posteroanterior chest radiograph and nonenhanced CT scans obtained through the mediastinum in 18-year-old man shows a large tumor involving the anterior, middle, and posterior mediastinum. Note the left pleural effusion. Biopsy confirmed a malignant teratoma.
Posteroanterior chest radiograph and nonenhanced ...

Posteroanterior chest radiograph and nonenhanced CT scans obtained through the mediastinum in 18-year-old man shows a large tumor involving the anterior, middle, and posterior mediastinum. Note the left pleural effusion. Biopsy confirmed a malignant teratoma.

Differential diagnosis. Posteroanterior (top left...Media file 18: Differential diagnosis. Posteroanterior (top left) and lateral (top right) chest radiographs and CT scans in mediastinal (bottom left and middle) and bone window (bottom right) show an Askin tumour with bone destruction.
Differential diagnosis. Posteroanterior (top left...

Differential diagnosis. Posteroanterior (top left) and lateral (top right) chest radiographs and CT scans in mediastinal (bottom left and middle) and bone window (bottom right) show an Askin tumour with bone destruction.

Posteroanterior (left) and lateral (right) chest ...Media file 19: Posteroanterior (left) and lateral (right) chest radiographs show a biopsy-proved posterior mediastinal dermoid.
Posteroanterior (left) and lateral (right) chest ...

Posteroanterior (left) and lateral (right) chest radiographs show a biopsy-proved posterior mediastinal dermoid.

More on Mediastinum, Germ Cell Tumors

Overview: Mediastinum, Germ Cell Tumors
Imaging: Mediastinum, Germ Cell Tumors
Follow-up: Mediastinum, Germ Cell Tumors
Multimedia: Mediastinum, Germ Cell Tumors
References
Further Reading

References

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Further Reading

Related eMedicine topics

Germ Cell Tumors

Mediastinal Cysts

Mediastinal Seminoma

Keywords

germ cell tumors, germ cell neoplasm, mediastinal germ cell tumor, GCTs, Klinefelter syndrome, teratoma, seminoma, epidermoid cyst, dermoids, dermoid cyst, mediastinal dermoid

Contributor Information and Disclosures

Author

Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, Consultant Radiologist, North Manchester General Hospital, The Pennine Acute NHS Trust, Manchester UK
Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR is a member of the following medical societies: American Institute of Ultrasound in Medicine, Royal College of Physicians, Royal College of Physicians and Surgeons of the United States, Royal College of Radiologists, and Royal College of Surgeons of England
Disclosure: Nothing to disclose.

Coauthor(s)

Klaus L Irion, MD, PhD, Consulting Staff, The Cardiothoracic Centre Liverpool NHS Trust, The Royal Liverpool University Hospital, UK
Klaus L Irion, MD, PhD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute
Sumaira MacDonald, MBChB, PhD, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Nigel Thomas, MBBS, Vice-Chair, Manchester (North) Research Ethics Committee; Honorary Lecturer, Visiting Professor, University of Salford, UK
Disclosure: Nothing to disclose.

Medical Editor

Kitt Shaffer, MD, PhD, Director of Undergraduate Medical Education, Associate Professor, Department of Radiology, Cambridge Health Alliance
Kitt Shaffer, MD, PhD is a member of the following medical societies: American Roentgen Ray Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

W Richard Webb, MD, Professor, Department of Radiology, University of California at San Francisco
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Kavita Garg, MD, Professor, Department of Radiology, University of Colorado Health Sciences Center
Kavita Garg, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, Radiological Society of North America, and Society of Thoracic Radiology
Disclosure: Nothing to disclose.

 
 
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