Intervention
Optical colonoscopy
The primary interventional procedure for the evaluation and removal of colonic polyps is optical colonoscopy, and gastroenterologists typically perform this procedure. Optical colonoscopy involves preparation to evacuate and clean the colon, followed by the passage of the long, fiberoptic colonoscopic tubing from the anus to the ileocecal valve. During this passage, all surfaces should be viewed en route or when the tubing is pulled back, through the video-enabled, distal tip of the flexible tube.
Air and saline are injected, the scope is rotated, and the tip is flexed or extended by using cables. The patient is rolled into different positions as needed. Conscious sedation is used to reduce spasm of the colon and to control pain. Polyps are removed by using a snare threaded to the distal end of the device.
Treatment
Daily aspirin (325 mg) appears to reduce the risk of cancers of the gastrointestinal tract. Similarly, celecoxib (Celebrex; 400 mg/d), which inhibits cyclo-oxygenase-2 (an enzyme involved in inflammation), may reduce the relative incidence of polyps 6-fold in as little as 6 months. Benefit has been observed after 6 months of treatment with exisulind (Aptosyn), which inhibits cyclic guanosine monophosphate and selectively induces apoptosis (programmed cell death) in abnormally growing, precancerous and cancerous cells (but not in normal cells).
Dietary supplements of calcium 1500 mg also may lower the risk of colon cancer. Turmeric, the spice that gives curry its yellow color, also may be protective.
Medicolegal Pitfalls
- Failure to obtain informed consent for biopsy or lesion removal before patients are medicated.
- Most facilities do not allow the patient to leave without a designated driver.
- Procedural risks include pain, bowel perforation, bleeding, and infection.
- Failure to diagnose cancer is a leading cause of malpractice litigation against gastroenterologists.22,23
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Further Reading
Keywords
virtual colonoscopy, virtual colonography, virtual coloscopy, computed colonoscopy, computed colonography, computed coloscopy, fiberoptic colonoscopy, fiberoptic colonography, fiberoptic coloscopy, optical colonoscopy, hyperplastic polyp, pedunculated adenoma, sessile adenoma, polyposis syndrome, familial adenomatous polyposis, FAP, Lynch syndrome, Lynch's syndrome, CT colonography, CTC
Follow-up: Colon, Polyps