eMedicine Specialties > Radiology > Gastrointestinal

Sprue: Follow-up

Author: J Kevin Smith, MD, PhD, Professor of Abdominal Imaging, Vice Chair for Veterans Affairs, Department of Radiology, University of Alabama at Birmingham; Chief of Service, Department of Radiology, Birmingham Veterans Affairs Medical Center
Coauthor(s): Carolyn R Bray Hebson, MD, Staff Physician, Department of Ophthalmology, Emory University School of Medicine
Contributor Information and Disclosures

Updated: Jun 2, 2009

Intervention

The most effective treatment for celiac patients is a strict gluten-free diet, which can protect them against complications. However, approximately 10-15% of celiac patients have a poor response to this dietary modification.3,17

In a prospective, double-blind, placebo-controlled study of trace amounts of gluten in 49 celiac disease patients on gluten-free diets, it was determined that contaminating gluten, according to Catassi et al, should be limited to a total of less than 50 mg a day in the treatment of patients with celiac disease.38

 


More on Sprue

Overview: Sprue
Imaging: Sprue
Follow-up: Sprue
Multimedia: Sprue
References
Further Reading

References

  1. van den Bosch HC, Tjon a Tham RT, Gooszen AW. Celiac disease: small-bowel enteroclysis findings in adult patients treated with a gluten-free diet. Radiology. Dec 1996;201(3):803-8. [Medline].

  2. Rettenbacher T, Hollerweger A, Macheiner P. Adult celiac disease: US signs. Radiology. May 1999;211(2):389-94. [Medline].

  3. Nehra V. New clinical issues in celiac disease. Gastroenterol Clin North Am. Jun 1998;27(2):453-65. [Medline].

  4. Heap GA, van Heel DA. Genetics and pathogenesis of coeliac disease. Semin Immunol. May 13 2009;[Medline].

  5. Burhenne HJ, Margulis AR. Practical Alimentary Tract Radiology. St Louis: Mosby-Year Book, Inc. 1993: 216-7, 389.

  6. Laghi A, Paolantonio P, Catalano C. MR imaging of the small bowel using polyethylene glycol solution as anoral contrast agent in adults and children with celiac disease:preliminary observations. AJR Am J Roentgenol. Jan 2003;180(1):191-4. [Medline].

  7. Rubio-Tapia A, Kyle RA, Kaplan EL, Johnson DR, Page W, Erdtmann F, et al. Increased Prevalence and Mortality in Undiagnosed Celiac Disease. Gastroenterology. Apr 10 2009;[Medline].

  8. Bova JG, Friedman AC, Weser E. Adaptation of the ileum in nontropical sprue: reversal of the jejunoilealfold pattern. AJR Am J Roentgenol. Feb 1985;144(2):299-302. [Medline].

  9. Heimberger DC, Weinsier RL. Handbook of Clinical Nutrition. St Louis: Mosby-Year Book, Inc. 1997;424:429-32.

  10. Merck. Malabsorption syndomes. In: The Merck Manual. Whitehouse Station, NJ: Merck & Co; 2003. [Full Text].

  11. Collin P, Reunala T, Pukkala E. Coeliac disease--associated disorders and survival. Gut. Sep 1994;35(9):1215-8. [Medline].

  12. Robertson PW, Frewin DB, Robertson AR. Plasma histamine levels following administration of radiographic contrast media. Br J Radiol. Nov 1985;58(695):1047-51. [Medline].

  13. Jones B, Bayless TM, Fishman EK. Lymphadenopathy in celiac disease: computed tomographic observations. AJR Am J Roentgenol. Jun 1984;142(6):1127-32. [Medline].

  14. Rubesin SE, Herlinger H, Saul SH. Adult celiac disease and its complications. Radiographics. Nov 1989;9(6):1045-66. [Medline].

  15. Masterson JB, Sweeney EC. The role of small bowel follow-through examination in the diagnosis ofcoeliac disease. Br J Radiol. Aug 1976;49(584):660-4. [Medline].

  16. Lomoschitz F, Schima W, Schober E. Enteroclysis in adult celiac disease: diagnostic value of specificradiographic features. Eur Radiol. Apr 2003;13(4):890-6. [Medline].

  17. Mike N, Udeshi U, Asquith P. Small bowel enema in non-responsive coeliac disease. Gut. Aug 1990;31(8):883-5. [Medline].

  18. Herlinger H, Maglinte DD. Jejunal fold separation in adult celiac disease: relevance ofenteroclysis. Radiology. Mar 1986;158(3):605-11. [Medline].

  19. Martinez G, Israel NR, White JJ. Celiac disease presenting as entero-enteral intussusception. Pediatr Surg Int. 2001;17(1):68-70. [Medline].

  20. Tomei E, Marini M, Messineo D. Computed tomography of the small bowel in adult celiac disease: thejejunoileal fold pattern reversal. Eur Radiol. 2000;10(1):119-22. [Medline].

  21. Billimoria PE, Fabian TM, Schulz EE. Computed tomography of intussusception in the bypassed jejunoileal segment. J Comput Assist Tomogr. Feb 1982;6(1):86-8. [Medline].

  22. Horton KM, Corl FM, Fishman EK. CT of nonneoplastic diseases of the small bowel: spectrum of disease. J Comput Assist Tomogr. May-Jun 1999;23(3):417-28. [Medline].

  23. Horton KM, Fishman EK. Uncommon inflammatory diseases of the small bowel: CT findings. AJR Am J Roentgenol. Feb 1998;170(2):385-8. [Medline].

  24. Strobl PW, Warshauer DM. CT diagnosis of celiac disease. J Comput Assist Tomogr. Mar-Apr 1995;19(2):319-20. [Medline].

  25. Kim JH, Ha HK, Sohn MJ. Usefulness of MR imaging for diseases of the small intestine: comparison with CT. Korean J Radiol. Jan-Mar 2000;1(1):43-50. [Medline].

  26. Lee JK, Marcos HB, Semelka RC. MR imaging of the small bowel using the HASTE sequence. AJR Am J Roentgenol. Jun 1998;170(6):1457-63. [Medline].

  27. Masselli G, Picarelli A, Gualdi G. Celiac disease: MR enterography and contrast enhanced MRI. Abdom Imaging. May 13 2009;[Medline].

  28. Beall DP, Regan F. MRI of bowel obstruction using the HASTE sequence. J Comput Assist Tomogr. Sep-Oct 1996;20(5):823-5. [Medline].

  29. Semelka RC, Kelekis NL, Thomasson D. HASTE MR imaging: description of technique and preliminary results in the abdomen. J Magn Reson Imaging. Jul-Aug 1996;6(4):698-9. [Medline].

  30. Cittadini G, Giasotto V, Garlaschi G. Transabdominal ultrasonography of the small bowel after oral administration of a non-absorbable anechoic solution: comparison with barium enteroclysis. Clin Radiol. Mar 2001;56(3):225-30. [Medline].

  31. del-Pozo G, Albillos JC, Tejedor D. Intussusception: US findings with pathologic correlation--the crescent-in-doughnut sign. Radiology. Jun 1996;199(3):688-92. [Medline].

  32. Riccabona M, Rossipal E. Sonographic findings in celiac disease. J Pediatr Gastroenterol Nutr. Aug 1993;17(2):198-200. [Medline].

  33. Riccabona M, Rossipal E. [Value of ultrasound in diagnosis of celiac disease]. Ultraschall Med. Feb 1996;17(1):31-3. [Medline].

  34. Alvarez D, Vazquez H, Bai JC. Superior mesenteric artery blood flow in celiac disease. Dig Dis Sci. Jul 1993;38(7):1175-82. [Medline].

  35. Ertem D, Acar Y, Karaa EK. A rare and often unrecognized cause of hematochezia and tenesmus in childhood: solitary rectal ulcer syndrome. Pediatrics. Dec 2002;110(6):e79. [Medline].

  36. Gustafson T, Sjolund K, Berg NO. Intestinal circulation in coeliac disease: an angiographic study. Scand J Gastroenterol. Oct 1982;17(7):881-5. [Medline].

  37. Cynn WS, Herasme VM, Levin BL. Mesenteric angiography of non-tropical sprue. Am J Roentgenol Radium Ther Nucl Med. Oct 1975;125(2):442-6. [Medline].

  38. Catassi C, Fabiani E, Iacono G, D'Agate C, Francavilla R, Biagi F, et al. A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease. Am J Clin Nutr. Jan 2007;85(1):160-6. [Medline].

  39. MGH. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-2001. A 52-year-old man with chronic anemia and sudden severe abdominal pain. N Engl J Med. Feb 15 2001;344(7):510-7. [Medline].

  40. Moser PP, Smith JK. CT findings of increased splanchnic circulation in a case of celiac sprue. Abdom Imaging. Jan-Feb 2004;29(1):15-7. [Medline].

  41. Robinson PJ, Bullen AW, Hall R. Splenic size and function in adult coeliac disease. Br J Radiol. Jun 1980;53(630):532-7. [Medline].

  42. Sinha SN, McArdle JP, Shepherd JJ. Hyperparathyroidism with chronic parathyroiditis in a multiple endocrineneoplasia patient. Aust N Z J Surg. Dec 1993;63(12):981-2. [Medline].

Further Reading

Related eMedicine topics

Celiac Sprue

Celiac Disease

Sprue, Tropical

Clinical guidelines

Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition - Professional Association.  2005 Jan.  19 pages.  NGC:004186

Celiac disease. National Institutes of Health (NIH) Consensus Development Panel on Celiac Disease - Independent Expert Panel
Office of Medical Applications of Research (NIH) - Federal Government Agency [U.S.].  2004 Aug 9.  15 pages.  NGC:003830

Clinical trials

Can a Very High Result From a Screening Test for Celiac Disease be Used to Diagnose Celiac Disease?

Infant Nutrition and Risk of Celiac Disease

Keywords

sprue, celiac disease, nontropical sprue, celiac sprue, idiopathic sprue, idiopathic steatorrhea, gluten enteropathy, gluten-sensitive enteropathy, gluten-induced enteropathy, gluten intolerance

Contributor Information and Disclosures

Author

J Kevin Smith, MD, PhD, Professor of Abdominal Imaging, Vice Chair for Veterans Affairs, Department of Radiology, University of Alabama at Birmingham; Chief of Service, Department of Radiology, Birmingham Veterans Affairs Medical Center
J Kevin Smith, MD, PhD is a member of the following medical societies: Alpha Omega Alpha, American College of Radiology, American Roentgen Ray Society, International Society for Magnetic Resonance in Medicine, Radiological Society of North America, and Society of Radiologists in Ultrasound
Disclosure: Nothing to disclose.

Coauthor(s)

Carolyn R Bray Hebson, MD, Staff Physician, Department of Ophthalmology, Emory University School of Medicine
Carolyn R Bray Hebson, MD is a member of the following medical societies: Alpha Omega Alpha
Disclosure: Nothing to disclose.

Medical Editor

Jocelyn D Chertoff, MD, Associate Professor of Radiology and Obstetrics/Gynecology, Dartmouth Medical School; Consulting Staff, Department of Diagnostic Radiology, Dartmouth-Hitchcock Medical Center
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Udo P Schmiedl, MD, PhD, Clinical Professor, Department of Radiology, University of Washington; Consulting Staff, Swedish Medical Center, University of Washington Medical Center, Seattle Radiologists
Udo P Schmiedl, MD, PhD is a member of the following medical societies: American College of Radiology and Radiological Society of North America
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Consulting Radiologist, Virginia Mason Medical Center; Clinical Assistant Professor of Radiology, University of Washington School of Medicine
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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