eMedicine Specialties > Radiology > Genitourinary

Cryptorchidism: Imaging

Author: Vikram S Dogra, MD, Professor of Diagnostic Radiology, University of Rochester, School of Medicine; Director, Division of Ultrasound, Associate Chair of Education and Research, Department of Imaging Sciences, University of Rochester Medical Center
Coauthor(s): Hamid Mojibian, MD, Radiology, Mercy Medical Center
Contributor Information and Disclosures

Updated: Apr 5, 2007

Computed Tomography

Findings

Cryptorchid testis is seen as an oval soft-tissue mass along the expected course of testicular descent. Uniform enhancement is seen with intravenous (IV) radiographic contrast.

Degree of Confidence

CT is almost as accurate as US in detecting an undescended testis in the inguinal region. CT and MRI are much better than US in detecting an undescended testis that is located abdominally. In 1 study evaluating undescended testis, CT and US accuracy were 96% and 91%, respectively.

False Positives/Negatives

A lymph node can be differentiated readily by the presence of fatty hilum and its characteristic location.

Magnetic Resonance Imaging

Findings

Perform MRI from the level of the kidneys to the level of the pelvic outlet. The pulse sequences used are T1, T2, and postgadolinium T1-weighted images in the axial and coronal planes. An oval mass that appears as low signal on T1-weighted images and high signal on T2-weighted images is characteristic of an undescended testis. Identification of the mediastinum testis is helpful.

Gadolinium-based contrast agents (gadopentetate dimeglumine [Magnevist], gadobenate dimeglumine [MultiHance], gadodiamide [Omniscan], gadoversetamide [OptiMARK], gadoteridol [ProHance]) have recently been linked to the development of nephrogenic systemic fibrosis (NSF) or nephrogenic fibrosing dermopathy (NFD). For more information, see the eMedicine topic Nephrogenic Fibrosing Dermopathy. The disease has occurred in patients with moderate to end-stage renal disease after being given a gadolinium-based contrast agent to enhance MRI or MRA scans. As of late December 2006, the FDA had received reports of 90 such cases. Worldwide, over 200 cases have been reported, according to the FDA. NSF/NFD is a debilitating and sometimes fatal disease. Characteristics include red or dark patches on the skin; burning, itching, swelling, hardening, and tightening of the skin; yellow spots on the whites of the eyes; joint stiffness with trouble movingor straightening the arms, hands, legs, or feet; pain deep in the hip bones or ribs; and muscle weakness. For more information, see the FDA Public Health Advisory or Medscape.

Degree of Confidence

MRI detects the malignant degeneration in cryptorchid testis well.

False Positives/Negatives

Occasionally, bowel loops and lymph nodes can mimic the undescended testis. CT is much better at differentiating the undescended testis from the bowel loop.

Ultrasonography

Findings

The most common location of cryptorchid testis is the inguinal canal (72%), followed by prescrotal (20%) and abdominal (8%) locations. The presence of an oval mass in the inguinal canal (relatively hypoechoic in echo texture with echogenic mediastinum) is diagnostic.

Degree of Confidence

US is the modality of choice for imaging a cryptorchid testis for the following reasons:

  • Of cryptorchid testes, 72% are in the inguinal canal; therefore, they are easily accessible.
  • US is readily available.
  • US is easy to schedule.

False Positives/Negatives

Rarely, an undescended testis can be confused with inguinal hernia; real time peristalsis confirms the presence of bowel.

Persistence of pars infravaginalis gubernaculi has been mistaken for the testis. The presence of an echogenic band (mediastinum testis) identifies the maldescended testis.

Angiography

Findings

Testicular venography has fallen out of favor because of the availability of noninvasive tests. The following findings are diagnostic:

  • Demonstrated presence of the pampiniform plexus
  • Visualization of testicular parenchyma
  • A blind-ending testicular vein (usually indicates absent testis)

Degree of Confidence

Angiography is accurate but invasive; thus, it is not preferred. Gadolinium infusion MR venography is an alternative noninvasive method of evaluating the undescended testis, especially the vanishing testis. It is superior to MR imaging alone.

More on Cryptorchidism

Overview: Cryptorchidism
Imaging: Cryptorchidism
Follow-up: Cryptorchidism
Multimedia: Cryptorchidism
References

References

  1. Bree RL, Hoang DT. Scrotal ultrasound. Radiol Clin North Am. Nov 1996;34(6):1183-205. [Medline].

  2. Dogra VS, Bhatt S, Rubens DJ. Sonographic evaluation of testicular torsion. Ultrasound Clin. 2006;1:55-66.

  3. Dogra VS, Gottlieb RH, Oka M. Sonography of the scrotum. Radiology. Apr 2003;227(1):18-36.

  4. Fritzsche PJ, Hricak H, Kogan BA. Undescended testis: value of MR imaging. Radiology. Jul 1987;164(1):169-73. [Medline].

  5. Gill B, Kogan S. Cryptorchidism. Current concepts. Pediatr Clin North Am. Oct 1997;44(5):1211-27. [Medline].

  6. Husmann DA, Levy JB. Current concepts in the pathophysiology of testicular undescent. Urology. Aug 1995;46(2):267-76. [Medline].

  7. Khatwa UA, Menon PS. Management of undescended testis. Indian J Pediatr. Jun 2000;67(6):449-54. [Medline].

  8. Kiely EA. Scientific basis of testicular descent and management implications for cryptorchidism. Br J Clin Pract. Jan-Feb 1994;48(1):37-41. [Medline].

  9. Koo HP, Bloom DA. Laparoscopy for the nonpalpable testis. Semin Laparosc Surg. Mar 1998;5(1):40-6. [Medline].

  10. Krone KD, Carroll BA. Scrotal ultrasound. Radiol Clin North Am. Mar 1985;23(1):121-39. [Medline].

  11. Nguyen HT, Coakley F, Hricak H. Cryptorchidism: strategies in detection. Eur Radiol. 1999;9(2):336-43. [Medline].

  12. Wolverson MK, Houttuin E, Heiberg E. Comparison of computed tomography with high-resolution real-time ultrasound in the localization of the impalpable undescended testis. Radiology. Jan 1983;146(1):133-6. [Medline].

Further Reading

Keywords

undescended testis, maldescended testis, atrophic testis, anorchia

Contributor Information and Disclosures

Author

Vikram S Dogra, MD, Professor of Diagnostic Radiology, University of Rochester, School of Medicine; Director, Division of Ultrasound, Associate Chair of Education and Research, Department of Imaging Sciences, University of Rochester Medical Center
Vikram S Dogra, MD is a member of the following medical societies: American College of Radiology, American Institute of Ultrasound in Medicine, American Roentgen Ray Society, Association of Program Directors in Radiology, Radiological Society of North America, Society of Radiologists in Ultrasound, and Society of Uroradiology
Disclosure: Nothing to disclose.

Coauthor(s)

Hamid Mojibian, MD, Radiology, Mercy Medical Center
Hamid Mojibian, MD is a member of the following medical societies: American College of Radiology
Disclosure: Nothing to disclose.

Medical Editor

John L Haddad, MD, Clinical Associate Professor, Department of Radiology, Weill Medical College of Cornell University; Director of Body MRI, Department of Radiology, Methodist Hospital in Houston
John L Haddad, MD is a member of the following medical societies: American College of Radiology, American Medical Association, and Radiological Society of North America
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Matthew D Rifkin, MD, Director, Department of Radiology, Good Samaritan Hospital
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Consulting Staff, Department of Radiology, Virginia Mason Medical Center
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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