eMedicine Specialties > Radiology > Genitourinary

Oncocytoma, Kidney: Follow-up

Author: Sanjeeva P Kalva, MD, Assistant Radiologist, Massachusetts General Hospital, Instructor in Radiology, Harvard Medical School, Department of Radiology, Massachusetts General Hospital
Coauthor(s): Dushyant Sahani, MD, Clinical Instructor of Abdominal Radiology and Intervention, Harvard Medical School; Assistant Radiologist, Department of Abdominal Imaging and Intervention, Massachusetts General Hospital
Contributor Information and Disclosures

Updated: Dec 29, 2008

Intervention

Medicolegal Pitfalls

  • Statistically, RCC is the most common solid renal mass.
  • Infrequently, benign tumors such as oncocytoma are encountered.
  • Because of the overlap in imaging features and histologic appearances between oncocytomas and RCCs, accurate differentiation on preoperative imaging or percutaneous biopsy remains difficult.
  • The diagnosis is often retrospectively established by means of gross pathology and microscopy with special stains.

Special Concerns

  • In select patient populations in whom surgery is not suitable, such as the elderly and those patients with extensive comorbid conditions, percutaneous needle biopsy may be useful to diagnose oncocytoma.
  • Once the diagnosis is confirmed, the lesions may be followed up with observation.
 


More on Oncocytoma, Kidney

Overview: Oncocytoma, Kidney
Imaging: Oncocytoma, Kidney
Follow-up: Oncocytoma, Kidney
Multimedia: Oncocytoma, Kidney
References
Further Reading
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References

  1. Schatz SM, Lieber MM. Update on oncocytoma. Curr Urol Rep. Feb 2003;4(1):30-5. [Medline].

  2. Zippel L. Zur kenntnis der onkocyten. Virchows Arch Pathol Anat Histopathol. 1942;308:360–82.

  3. Klein MJ, Valensi QJ. Proximal tubular adenomas of kidney with so-called oncocytic features. A clinicopathologic study of 13 cases of a rarely reported neoplasm. Cancer. 1976;38:906-14. [Medline].

  4. Dechet CB, Bostwick DG, Blute ML, Bryant SC, Zincke H. Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma. J Urol. Jul 1999;162(1):40-2. [Medline].

  5. Snyder ME, Bach A, Kattan MW, et al. Incidence of benign lesions for clinically localized renal masses smaller than 7 cm in radiological diameter: influence of sex. J Urol. Dec 2006;176(6 Pt 1):2391-5; discussion 2395-6. [Medline].

  6. de la Cruz Burgos R, Martel Villagrán J. [Renal oncocytoma. Fundamental radiologic manifestations and enhancement patterns in tri-phase helical CT] [Spanish]. Radiologia. Mar-Apr 2007;49(2):109-14. [Medline].

  7. Algaba F. Renal adenomas: pathological differential diagnosis with malignant tumors. Adv Urol. 2008;974848. [Medline].

  8. Hruby GW, Fine JK, Landman J. Ultrasound-guided percutaneous ablation of a renal mass in a renal allograft. Urology. Oct 2006;68(4):891.e5-6. [Medline].

  9. Bahrami A, Schwartz MR, Ayala AG, Goldfarb RA, Brady JR, Takei H. Concurrent angiomyolipoma and two oncocytomas in the same kidney. Ann Diagn Pathol. Apr 2007;11(2):132-6. [Medline].

  10. Mistry R, Manikandan R, Williams P, Philip J, Littler P, Foster CS, et al. Implications of computer tomography measurement in the management of renal tumours. BMC Urol. Nov 4 2008;8:13. [Medline].

  11. Prasad SR, Surabhi VR, Menias CO, Raut AA, Chintapalli KN. Benign renal neoplasms in adults: cross-sectional imaging findings. AJR Am J Roentgenol. Jan 2008;190(1):158-64. [Medline].

  12. Pedrosa I, Sun MR, Spencer M, Genega EM, Olumi AF, Dewolf WC, et al. MR imaging of renal masses: correlation with findings at surgery and pathologic analysis. Radiographics. Jul-Aug 2008;28(4):985-1003. [Medline].

  13. Fan L, Lianfang D, Jinfang X, Yijin S, Ying W. Diagnostic efficacy of contrast-enhanced ultrasonography in solid renal parenchymal lesions with maximum diameters of 5 cm. J Ultrasound Med. Jun 2008;27(6):875-85. [Medline].

  14. Chao DH, Zisman A, Pantuck AJ, et al. Changing concepts in the management of renal oncocytoma. Urology. May 2002;59(5):635-42. [Medline].

  15. Davidson AJ, Hayes WS, Hartman DS, McCarthy WF, Davis CJ Jr. Renal oncocytoma and carcinoma: failure of differentiation with CT. Radiology. Mar 1993;186(3):693-6. [Medline]. [Full Text].

  16. Kutikov A, Fossett LK, Ramchandani P, et al. Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging. Urology. Oct 2006;68(4):737-40. [Medline].

  17. Newhouse JH, Wagner BJ. Renal oncocytomas. Abdom Imaging. May-Jun 1998;23(3):249-55. [Medline].

  18. Pretorius ES, Siegelman ES, Ramchandani P, Cangiano T, Banner MP. Renal neoplasms amenable to partial nephrectomy: MR imaging. Radiology. Jul 1999;212(1):28-34. [Medline]. [Full Text].

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Keywords

oncocytoma of the kidney, benign renal tumor, renal neoplasms, renal cell carcinomas, RCCs

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Contributor Information and Disclosures

Author

Sanjeeva P Kalva, MD, Assistant Radiologist, Massachusetts General Hospital, Instructor in Radiology, Harvard Medical School, Department of Radiology, Massachusetts General Hospital
Sanjeeva P Kalva, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Cordis Endovascular Honoraria Speaking and teaching; Cook Grant/research funds Other; Cordis Grant/research funds Other; Angiodynamics Grant/research funds None

Coauthor(s)

Dushyant Sahani, MD, Clinical Instructor of Abdominal Radiology and Intervention, Harvard Medical School; Assistant Radiologist, Department of Abdominal Imaging and Intervention, Massachusetts General Hospital
Disclosure: Nothing to disclose.

Medical Editor

Steven Perlmutter, MD, FACR, Associate Professor of Clinical Radiology, School of Medicine at Stony Brook University; Medical Director of Radiology, Peconic Bay Medical Center
Steven Perlmutter, MD, FACR is a member of the following medical societies: American College of Radiology, American Institute of Ultrasound in Medicine, American Medical Association, American Roentgen Ray Society, Association of Program Directors in Radiology, Association of University Radiologists, Medical Society of the State of New York, Radiological Society of North America, Society of Breast Imaging, Society of Nuclear Medicine, and Society of Uroradiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Arnold C Friedman, MD, FACR, Associate Chairman, Department of Radiology, University of Florida Health Science Center; Chief, Department of Radiology, Shands-Jacksonville Hospital
Arnold C Friedman, MD, FACR is a member of the following medical societies: American College of Radiology, American Institute of Ultrasound in Medicine, American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Consulting Radiologist, Virginia Mason Medical Center; Clinical Assistant Professor of Radiology, University of Washington School of Medicine
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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