Multimedia
![]() | Media file 1: Coronal noncontrast T1-weighted MRI reveals a large intraorbital mass (arrow) centered on the optic nerve. |
![]() | Media file 2: Coronal postgadolinium T1-weighted MRI with fat saturation (same patient as in Image above) reveals diffuse, intense enhancement of the intraorbital mass (arrow). |
![]() | Media file 4: Axial postgadolinium T1-weighted MRI with fat saturation in a 6-year-old girl demonstrates enhancement of the intracranial optic nerve (arrow), which is slightly expanded. |
![]() | Media file 6: Axial noncontrast T1-weighted MRI in a 46-year-old man demonstrates enlargement of both optic tracts (arrowheads) and the optic chiasm (arrow). |
More on Optic Nerve Glioma |
| Overview: Optic Nerve Glioma |
| Imaging: Optic Nerve Glioma |
| Follow-up: Optic Nerve Glioma |
Multimedia: Optic Nerve Glioma |
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References
Wilhelm H. Primary optic nerve tumours. Curr Opin Neurol. Feb 2009;22(1):11-8. [Medline].
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Hendrix LE, Kneeland JB, Haughton VM, et al. MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique. AJNR Am J Neuroradiol. Jul-Aug 1990;11(4):749-54. [Medline].
Messori A, Salvolini U. Hybrid phakomatosis: from initial CT observation to molecular studies. AJNR Am J Neuroradiol. Aug 2004;25(7):1297-8.
Listernick R, Charrow J, Greenwald MJ, et al. Optic gliomas in children with neurofibromatosis type 1. J Pediatr. May 1989;114(5):788-92. [Medline].
Hollander MD, FitzPatrick M, O''Connor SG, et al. Optic gliomas. Radiol Clin North Am. Jan 1999;37(1):59-71, ix. [Medline].
Millar WS, Tartaglino LM, Sergott RC, et al. MR of malignant optic glioma of adulthood. AJNR Am J Neuroradiol. Sep 1995;16(8):1673-6. [Medline].
Thiagalingam S, Flaherty M, Billson F. Neurofibromatosis type 1 and optic pathway gliomas: follow-up of 54 patients. Ophthalmology. Mar 2004;111(3):568-77. [Medline].
Kornreich L, Blaser S, Schwarz M, et al. Optic pathway glioma: correlation of imaging findings with the presence of neurofibromatosis. AJNR Am J Neuroradiol. Nov-Dec 2001;22(10):1963-9. [Medline].
Tumialan LM, Dhall SS, Biousse V. Optic nerve glioma and optic neuritis mimicking one another: case report. Neurosurgery. Jul 2005;57(1):E190; discussion E190.
Taylor T, Jaspan T, Milano G, Gregson R, Parker T, Ritzmann T, et al. Radiological classification of optic pathway gliomas: experience of a modified functional classification system. Br J Radiol. Oct 2008;81(970):761-6. [Medline].
Forte R, Cennamo G, Breve MA. Three-Dimensional Ultrasound of Ophthalmic Pathologies. Ophthalmologica. Jan 31 2009;223(3):183-187. [Medline].
Walrath JD, Engelbert M, Kazim M. Magnetic resonance imaging evidence of optic nerve glioma progression into and beyond the optic chiasm. Ophthal Plast Reconstr Surg. Nov-Dec 2008;24(6):473-5. [Medline].
Buffa A, Vannelli S, Peretta P. [NF1 and gliomas: the importance of the MRI]. Minerva Pediatr. Apr 2008;60(2):259-60. [Medline].
Kwon Y, Bae JS, Kim JM. Visual changes after gamma knife surgery for optic nerve tumors. Report of three cases. J Neurosurg. Jan 2005;102 Suppl:143-6.
Further Reading
Related eMedicine topics
Neurofibromatosis Type 1 (from Radiology)
Neurofibromatosis, Type 1 (from Neurology)
Optic Neuropathy, Compressive
Sudden Visual Loss (from Neurology)
Sudden Visual Loss (from Ophthalmology)
Clinical guidelines
Eye Examination in Infants, Children, and Young Adults by Pediatricians
Neurofibromatosis Type 1 in Genetic Counseling Practice: Recommendations of the National Society of Genetic Counselors
Clinical studies
Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas
Trial to Evaluate the Safety of Lovastatin in Adults With Neurofibromatosis Type I (NF1)
Keywords
optic nerve glioma, optic pathway glioma, optic glioma, neurofibromatosis, neurofibromatosis type 1, NF-1, neurofibromatosis 1, von Recklinghausen disease, optic nerve disease, hybrid phakomatosis














Multimedia: Optic Nerve Glioma