Intervention
The only intervention that has been shown to be effective in these tumors is a surgical approach. Neither radiation therapy nor chemotherapy has been proven effective.
Treatment options for adamantinoma are surgical and include either marginal or en bloc resection. Marginal resection of the tumor has been shown to be effective in less than one half of the cases studied; however, en bloc resection generally prevents local recurrence of the tumor.
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References
Dorfman HD, Czerniak. Bone Tumors. Mosby-Year Book;1998:949-73.
Kitsoulis P, Charchanti A, Paraskevas G, Marini A, Karatzias G. Adamantinoma. Acta Orthop Belg. Aug 2007;73(4):425-31. [Medline].
Gleason BC, Liegl-Atzwanger B, Kozakewich HP, Connolly S, Gebhardt MC, Fletcher JA, et al. Osteofibrous Dysplasia and Adamantinoma in Children and Adolescents: A Clinicopathologic Reappraisal. Am J Surg Pathol. Mar 2008;32(3):363-376. [Medline].
Jain D, Jain VK, Vasishta RK, Ranjan P, Kumar Y. Adamantinoma: A clinicopathological review and update. Diagn Pathol. Feb 15 2008;3(1):8. [Medline].
Resnick D. Diagnosis of Bone and Joint Disorders. Vol 6. Philadelphia, PA: W. B. Saunders Co;1995:3882-4.
Taveras JM. Radiology, Diagnosis, Imaging Intervention. Vol 5. Philadelphia, PA: Lippincott Williams & Wilkins;1993.
Fischer B. Uber ein primares Adamantinom der Tibia. 12. Frankfurt: Zeitschr. f. Path.; 1913:422-441.
Further Reading
Keywords
long bone tumors, classic adamantinomas, differentiated adamantinomas, adamantinomous tumors, primary adamantinomas
Follow-up: Adamantinoma