Updated: Sep 18, 2009
The most common mass in the popliteal fossa, Baker cyst, also termed popliteal cyst, results from fluid distention of the gastrocnemio-semimembranosus bursa. The eponym honors the work of Dr William Morrant Baker. In 1877, Baker described 8 cases of periarticular cysts caused by synovial fluid that had escaped from the knee joint and formed a new sac outside the joint.[1 ]The common underlying conditions were osteoarthritis and Charcot joint.[2 ]
A Baker cyst may serve as a protective mechanism for the knee. Intrinsic intra-articular disorders cause joint effusion. The knee effusion is displaced into the Baker cyst, thus reducing potentially destructive pressure in the joint space. Jayson and Dixon postulated that joint effusion and fibrin are pumped from the knee joint into the Baker cyst but not in the reverse direction, because of a valvelike communication, such as a ball valve or a Bunsen valve (see Image below and Image 1 in Multimedia).[5 ]
The prevalence of Baker cysts depends on patient population and imaging modality, as shown in Tables 1 and 2 (see below).
Table 1. Prevalence of Baker Cysts Based on Diagnostic Modalities
| Diagnostic Modalities | Prevalence, % |
| Magnetic resonance imaging (MRI) | 5-18 |
| Cadaveric dissections | 30 |
| Arthroscopy | 37 |
| Ultrasound | 40-42 |
| Arthrography | 5-46 |
Table 2. Prevalence of Baker Cysts Based on Patient Populations
| Patient Populations | Prevalence, % |
| Rheumatoid Arthritis | 5-58 |
| Osteoarthritis | 42 |
| Internal derangements | 5-18 |
Refer to Special Concerns for a detailed discussion.
No racial predilection exists.
No sex predilection exists.
Refer to Pathophysiology for a detailed discussion.
Table 3 lists the most common symptoms in patients with a Baker cyst, as found in a study of 38 patients by Bryan and colleagues.[7 ]
Table 3. Symptoms of Baker Cyst
| Symptoms | Frequency | |
| Popliteal mass or swelling | 29/38 | 76% |
| Aching | 12/38 | 32% |
| Knee effusion | 12/38 | 32% |
| Thrombophlebitis | 5/38 | 13% |
| Clicking of the knee | 4/38 | 11% |
| Buckling of the knee | 4/38 | 11% |
| Locking of the knee | 1/38 | 3% |
In the study, a popliteal mass was the most common presenting complaint or symptom. A significant number of patients (13%) had pseudothrombophlebitis, a syndrome in which symptoms simulate those of deep venous thrombosis (DVT). Therefore, DVT should be excluded in patients with Baker cyst and leg swelling.
Medical conditions associated with Baker cysts, in descending order of frequency, are as follows:
Arthritis is the most common condition associated with Baker cysts, with osteoarthritis probably being the most frequent cause among the arthritides.[8 ]Although the prevalence of Baker cysts in patients with inflammatory arthritis is higher than in patients with osteoarthritis, osteoarthritis is much more common than inflammatory arthritis. Using ultrasonography, Fam and colleagues found that 21 of 50 patients (42%) with osteoarthritis had Baker cysts.[9 ]Bilateral cysts were seen in 8 patients (16%). The occurrence of Baker cysts relates directly to the presence of knee effusion and the severity of the osteoarthritis.
In 99 consecutive patients with RA, Andonopoulos and coauthors demonstrated Baker cysts on ultrasonograms of 47 patients (48%).[10 ]Twenty of the 99 patients (20%) had bilateral cysts. Of 198 knees, 67 (34%) had Baker cysts, yet only 29 cysts (43%) were diagnosed clinically.
Baker cysts appear much less frequently in children than in adults. The prevalence of Baker cysts in asymptomatic children examined ultrasonographically was 2.4%. The prevalence of Baker cyst in children undergoing MRI examination of the knee was 6.3%. None of the children with Baker cyst demonstrated an associated ACL or meniscal tear. Four patients (8%) had osteochondritis dissecans (n = 2), septic arthritis (n = 1), or juvenile RA (n = 1). In most children with Baker cysts (82%), the cysts disappeared without intervention (84%) or caused no symptoms (16%). However, in children with arthritis, Baker cysts are common.
In a study of 44 children with knee arthritis, ultrasonography detected a Baker cyst in 27 children (61%), most of whom (80%) had juvenile RA.[11 ]The remaining causes of arthritis in the study included spondyloarthropathy, psoriatic arthritis, septic arthritis, and systemic lupus erythematosus. Cysts were followed prospectively with serial ultrasonography for 18-24 months. Cysts resolved with the resolution of suprapatellar effusion. Reports of Baker cyst associated with gout, Reiter syndrome, psoriasis, and systemic lupus erythematosus exist. The common underlying pathology for these medical conditions is synovial proliferation with effusion.
Arthrography is more sensitive than ultrasonography in detecting Baker cysts. In 24 patients with a possible Baker cyst, arthrography of both knees was performed immediately after ultrasonography. The latter detected a cyst in 19 of the 48 knees (40%), while arthrography demonstrated a cyst in 22 knees (46%). The increased sensitivity of arthrography is probably the result of its ability to distend the bursa.
Guerra and colleagues found a 30% incidence of popliteal bursa in cadaveric anatomic dissection of older patients.[12 ]Using diagnostic arthroscopy, Johnson and coauthors demonstrated a 37% incidence of popliteal bursa.[13 ]The incidence of Baker cysts detected through MRI of the knee varies (5-18%) according to the patient population. Initially, Fielding and colleagues reported an association between Baker cyst and tear of the medial meniscus or complete tear of the ACL.[14 ]Stone and colleagues demonstrated that 84% of Baker cysts detected on magnetic resonance images had meniscal tears.[15 ]Most tears were observed in the posterior horn of the medial meniscus.
Subsequently, Miller and coauthors confirmed a significant association of Baker cyst with effusion, meniscal tears, and degenerative arthropathy.[16 ]The probability of a Baker cyst in the presence of any 1 variable (ie, association) is P = 0.08-0.10, of any 2 variables is P = 0.19-0.21, and of all 3 variables is P = 0.38. However, no association was found between Baker cyst and ACL tear.
Sansone and colleagues reviewed the incidence of associated intra-articular disorders in a series of 1001 adult patients undergoing MRI of the knee.[17 ]They found that the most common associated lesions were meniscal tears, chondral lesions, and ACL tears.
Treatment
The treatment of Baker cysts is conservative and includes the use of nonsteroidal anti-inflammatory agents, ice, and assisted weight bearing, in addition to the correction of underlying intra-articular disorders. Internal derangements of the knee can be treated with therapeutic arthroscopy.[18 ]Total knee arthroplasty is reserved for severe osteoarthritis.[19,20 ]
Radioactive synoviorthesis can be used to treat inflammatory arthritides and hemophilia. Prior to this treatment, arthrography should be performed to exclude a leaking Baker cyst (see Image below and Image 19 in Multimedia). A leaking Baker cyst would release radionuclide agent outside the knee joint, which is a contraindication to radioactive synoviorthesis.
Imaging evaluation of a Baker cyst begins with conventional radiography to detect a soft-tissue mass (see Image below and Image 2 in Multimedia), internal calcifications, displacement of an atherosclerotic popliteal artery, and the unusual case of adjacent bony involvement from a large and/or long-standing cyst.[8 ]
Color Doppler imaging can confirm the absence of vascular flow within the mass to exclude a popliteal artery aneurysm or cystic adventitial degeneration of a popliteal artery (see Images below and Image 5, Image 6 in Multimedia).[21 ]Ultrasonography can concomitantly exclude a coexisting DVT created by subjacent mass effect. The weakness of ultrasonography is related to the difficulty in establishing a true connection to the joint space proper, which is essential for discriminating between a Baker cyst and other potentially harmful conditions in the differential diagnosis (see the discussion on magnetic resonance evaluation, below).
The communication with the joint by way of the gastrocnemio-semimembranosus bursa is deep within the popliteal space, adjacent to the dense posterior femoral cortex. The ultrasonography probe is placed over the popliteal skin surface, and because this thin, necklike connection to the joint is anterior to the cyst, the mere presence of a large or complex Baker cyst may obscure the visualization of this connection.
Previously, Baker cysts were commonly detected by conventional arthrography or by computed tomography (CT) scanning. Arthrography demonstrates the cyst only if the iodinated contrast material that is injected into the joint during arthrography communicates with the cyst under the pressure of the injection. CT scanning can delineate a low to intermediate attenuation mass, which normally measures from 20 to -10 Hounsfield units, in the posteromedial popliteal space. CT scanning can easily delineate secondary findings, such as intracystic osseous fragments, mass effect, wall thickening, and bony erosion.
In current radiologic practice, Baker cysts are often detected on MRI evaluations of the knee (performed for any indication). Sansone and colleagues studied 1001 randomly selected patients who were submitted for a knee MRI examination; the authors reported the frequency of Baker cysts to be 4.7%, but the frequency in the literature varies. The advantages of MRI are derived from the superior soft-tissue contrast resolution that it affords and from the modality's multiplanar capability, which help to determine the extent and composition of the Baker cyst.
However, one of the most important benefits of employing MRI is the ability to use the axial plane to establish positive identification of the high – signal intensity, fluid-filled neck of the cyst that connects the cyst to the joint space (see Image below and Image 7 in Multimedia). This makes it possible to discriminate between a benign Baker cyst and one of the uncommon, but clinically important, types of cystic tumors, such as myxoid liposarcoma, that can occur in the popliteal fossa.
Deep Venous Thrombosis, Lower Extremity
Vascular masses
Nonvascular masses
Imaging evaluation of a popliteal mass begins with conventional radiography to detect a soft-tissue mass, calcifications, and bony involvement. A Baker cyst appears as a soft-tissue mass in the posteromedial knee joint (see Image below and Image 2 in Multimedia).
On a CT scan, a Baker cyst appears as a fluid-containing mass located behind the medial femoral condyle and between the tendons of the medial head of the gastrocnemius and semimembranosus muscles. A space-occupying lesion in the posteromedial knee suggests the diagnosis but is not always sufficient to exclude other etiologies, for which MRI or ultrasonography is more specific.
CT scanning is not as sensitive as MRI in detecting an internal derangement, which may be the cause of a Baker cyst. In addition, the definitive diagnosis of a Baker cyst may not be made without the injection of air and/or iodinated contrast material into the knee joint.
On MRI, a Baker cyst appears as a homogeneous, high – signal intensity, cystic mass behind the medial femoral condyle; a thin, fluid-filled neck interdigitates between the tendons of the medial head of the gastrocnemius and semimembranosus muscles (see Image below and Image 7 in Multimedia).[22 ]
In addition, intravenously administered gadolinium can detect synovial enhancement (see Images below and Image 12, Image 13 in Multimedia) and pannus formation in RA in the cyst and in the joint space proper, prior to the radiographic detection of well-known signs of RA much later in the course of the disease (erosion, uniform joint space loss without marked osteophytosis, periarticular osteopenia, soft-tissue swelling).
Ultrasonography is a very helpful imaging technique in the evaluation of a popliteal mass.[23,24,25 ] The modality can be used to determine whether the popliteal mass is a cyst or a solid mass. A simple Baker cyst appears as an anechoic mass with posterior acoustic enhancement that communicates with the knee joint. Findings on an ultrasonogram relate to the criteria of a simple cyst, which include an anechoic mass, a sharply defined posterior wall, and posterior acoustic enhancement. A complex Baker cyst has internal echoes within the hypoechoic mass (see Images below and Image 3, Image 4 in Multimedia). Calcified, loose bodies within a Baker cyst appear as mobile, intraluminal, echogenic foci with distal acoustic shadowing, an appearance similar to that of cholelithiasis in a gallbladder. An additional advantage of ultrasonography is that it can exclude a coexisting DVT.
This is the fastest, most cost-effective manner in which to diagnose a Baker cyst.
A cyst that is too large or complex may obscure visualization of the fluid-filled connection to the joint space proper, leading to a false-positive diagnosis.
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Baker cyst, Baker's cyst, popliteal cyst, popliteal bursa, gastrocnemio-semimembranosus bursa, gastrocnemio-semimembranous bursa, gastrocnemiosemimembranosus bursa, gastrocnemiosemimembranous bursa
Liem T Bui-Mansfield, MD, Associate Professor, Department of Radiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland
Liem T Bui-Mansfield, MD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.
Rush A Youngberg, MD, Chief of Musculoskeletal Radiology, Department of Radiology, Madigan Army Medical Center
Disclosure: Nothing to disclose.
David S Levey, MD, PhD, Orthopedic/Spine MRI TeleRadiologist, Radsource, LLC
David S Levey, MD, PhD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Texas Medical Association
Disclosure: Nothing to disclose.
Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.
Javier Beltran, MD, Chair, Department of Radiology, Maimonides Medical Center
Disclosure: Nothing to disclose.
Robert M Krasny, MD, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.
Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.
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Finnish Medical Society Duodecim - Professional Association. 2000 Apr 18 (revised 2007 Jan 11). Various pagings. NGC:005501
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