eMedicine Specialties > Radiology > Musculoskeletal

Chondrosarcoma: Multimedia

Author: Geoff Hide, MBBS, MRCP, FRCR, Consultant Musculoskeletal Radiologist, Department of Radiology, Freeman Hospital; Honorary Clinical Lecturer, Faculty of Medical Sciences, University of Newcastle upon Tyne
Contributor Information and Disclosures

Updated: Nov 3, 2009

Multimedia

Frontal radiograph of the left fibula head demons...Media file 1: Frontal radiograph of the left fibula head demonstrates a lucent lesion that contains the typical chondroid matrix calcification. Low-grade tumor.
Frontal radiograph of the left fibula head demons...

Frontal radiograph of the left fibula head demonstrates a lucent lesion that contains the typical chondroid matrix calcification. Low-grade tumor.

Frontal radiograph of the left acetabulum demonst...Media file 2: Frontal radiograph of the left acetabulum demonstrates an expansile lucent lesion with no internal matrix calcification. Low-grade central tumor.
Frontal radiograph of the left acetabulum demonst...

Frontal radiograph of the left acetabulum demonstrates an expansile lucent lesion with no internal matrix calcification. Low-grade central tumor.

Bone-window CT scan of left acetabulum demonstrat...Media file 3: Bone-window CT scan of left acetabulum demonstrates matrix calcification in the expansile lucent lesion in the anterior column (see also Images 2, 4, and 5 in Multimedia Section). Low-grade central tumor.
Bone-window CT scan of left acetabulum demonstrat...

Bone-window CT scan of left acetabulum demonstrates matrix calcification in the expansile lucent lesion in the anterior column (see also Images 2, 4, and 5 in Multimedia Section). Low-grade central tumor.

T2-weighted axial MRI of the pelvis demonstrates ...Media file 4: T2-weighted axial MRI of the pelvis demonstrates the high signal intensity of the acetabular lesion (same patient as in Images 2-3, 5 in Multimedia). Low-grade central tumor.
T2-weighted axial MRI of the pelvis demonstrates ...

T2-weighted axial MRI of the pelvis demonstrates the high signal intensity of the acetabular lesion (same patient as in Images 2-3, 5 in Multimedia). Low-grade central tumor.

T1-weighted axial MRI of the pelvis demonstrates ...Media file 5: T1-weighted axial MRI of the pelvis demonstrates the low signal intensity of the acetabular lesion (same patient as in Images 2-4 in Multimedia). Low-grade central tumor.
T1-weighted axial MRI of the pelvis demonstrates ...

T1-weighted axial MRI of the pelvis demonstrates the low signal intensity of the acetabular lesion (same patient as in Images 2-4 in Multimedia). Low-grade central tumor.

Frontal radiograph of right side of upper abdomen...Media file 6: Frontal radiograph of right side of upper abdomen demonstrates a destructive, expansile lesion of the 12th rib. The lesion contains irregular calcification. High-grade central tumor.
Frontal radiograph of right side of upper abdomen...

Frontal radiograph of right side of upper abdomen demonstrates a destructive, expansile lesion of the 12th rib. The lesion contains irregular calcification. High-grade central tumor.

CT of the right side of the upper abdomen demonst...Media file 7: CT of the right side of the upper abdomen demonstrates the expansile tumor with a large associated soft tissue mass containing foci of calcification (see also Image 6 in Multimedia Section). High-grade central tumor.
CT of the right side of the upper abdomen demonst...

CT of the right side of the upper abdomen demonstrates the expansile tumor with a large associated soft tissue mass containing foci of calcification (see also Image 6 in Multimedia Section). High-grade central tumor.

Frontal radiograph of the pelvis demonstrates ext...Media file 8: Frontal radiograph of the pelvis demonstrates extensive calcification overlying the left ilium and in the lateral soft tissues. No bone destruction is shown. High-grade secondary peripheral tumor.
Frontal radiograph of the pelvis demonstrates ext...

Frontal radiograph of the pelvis demonstrates extensive calcification overlying the left ilium and in the lateral soft tissues. No bone destruction is shown. High-grade secondary peripheral tumor.

CT scan of the pelvis demonstrates a large soft t...Media file 9: CT scan of the pelvis demonstrates a large soft tissue mass that contains calcification arising from a broad-based sessile osteochondroma on the posterior aspect of the ilium (see also Images 8 and 10 in Multimedia Section). High-grade secondary peripheral tumor.
CT scan of the pelvis demonstrates a large soft t...

CT scan of the pelvis demonstrates a large soft tissue mass that contains calcification arising from a broad-based sessile osteochondroma on the posterior aspect of the ilium (see also Images 8 and 10 in Multimedia Section). High-grade secondary peripheral tumor.

T2-weighted axial MRI of the pelvis demonstrates ...Media file 10: T2-weighted axial MRI of the pelvis demonstrates a lobulated high-signal-intensity soft tissue with local-signal-intensity septa arising from the osteochondroma on the posterior aspect of the ilium (same patient as in Image 9 in Multimedia). Several areas of low signal intensity are shown; these correspond to focal areas of dense calcification. This appearance is typical of cartilaginous material. High-grade secondary peripheral tumor.
T2-weighted axial MRI of the pelvis demonstrates ...

T2-weighted axial MRI of the pelvis demonstrates a lobulated high-signal-intensity soft tissue with local-signal-intensity septa arising from the osteochondroma on the posterior aspect of the ilium (same patient as in Image 9 in Multimedia). Several areas of low signal intensity are shown; these correspond to focal areas of dense calcification. This appearance is typical of cartilaginous material. High-grade secondary peripheral tumor.

Lateral radiograph of the distal femur in a patie...Media file 11: Lateral radiograph of the distal femur in a patient with hereditary multiple exostoses. Several osteochondromas of varying appearances arise from the metaphyseal region; these typically grow away from the joint. Soft tissue calcification is shown overlying the most posterior osteochondroma. High-grade secondary peripheral tumor.
Lateral radiograph of the distal femur in a patie...

Lateral radiograph of the distal femur in a patient with hereditary multiple exostoses. Several osteochondromas of varying appearances arise from the metaphyseal region; these typically grow away from the joint. Soft tissue calcification is shown overlying the most posterior osteochondroma. High-grade secondary peripheral tumor.

CT scan of the distal femur demonstrates a broad-...Media file 12: CT scan of the distal femur demonstrates a broad-based osteochondroma with a thick overlying soft tissue cap that contains focal calcification. The metaphyseal contour is irregular because of the presence of several other osteochondromas in this patient with hereditary multiple exostoses (see also Images 11 and 13 in Multimedia Section). High-grade secondary peripheral tumor.
CT scan of the distal femur demonstrates a broad-...

CT scan of the distal femur demonstrates a broad-based osteochondroma with a thick overlying soft tissue cap that contains focal calcification. The metaphyseal contour is irregular because of the presence of several other osteochondromas in this patient with hereditary multiple exostoses (see also Images 11 and 13 in Multimedia Section). High-grade secondary peripheral tumor.

Fast spin-echo T2-weighted axial MRI of the dista...Media file 13: Fast spin-echo T2-weighted axial MRI of the distal femur in a patient with hereditary multiple exostoses (same patient as in Images 11-12 in Multimedia). Image demonstrates the thick cartilage cap overlying a broad-based osteochondroma. Areas of focal reduced signal intensity in the cartilage cap correspond to foci of dense calcification. High-grade secondary peripheral tumor.
Fast spin-echo T2-weighted axial MRI of the dista...

Fast spin-echo T2-weighted axial MRI of the distal femur in a patient with hereditary multiple exostoses (same patient as in Images 11-12 in Multimedia). Image demonstrates the thick cartilage cap overlying a broad-based osteochondroma. Areas of focal reduced signal intensity in the cartilage cap correspond to foci of dense calcification. High-grade secondary peripheral tumor.

More on Chondrosarcoma

Overview: Chondrosarcoma
Imaging: Chondrosarcoma
Follow-up: Chondrosarcoma
Multimedia: Chondrosarcoma
References
Further Reading

References

  1. Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Semin Musculoskelet Radiol. 2000;4(1):59-71. [Medline].

  2. Marco RA, Gitelis S, Brebach GT, Healey JH. Cartilage tumors: evaluation and treatment. J Am Acad Orthop Surg. Sep-Oct 2000;8(5):292-304. [Medline].

  3. Gelderblom H, Hogendoorn PC, Dijkstra SD, van Rijswijk CS, Krol AD, Taminiau AH, et al. The clinical approach towards chondrosarcoma. Oncologist. Mar 2008;13(3):320-9. [Medline].

  4. Giuffrida AY, Burgueno JE, Koniaris LG, Gutierrez JC, Duncan R, Scully SP. Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database. J Bone Joint Surg Am. May 2009;91(5):1063-72. [Medline].

  5. Murphey MD, Flemming DJ, Boyea SR, et al. Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. Radiographics. Sep-Oct 1998;18(5):1213-37; quiz 1244-5. [Medline].

  6. Resnik D, Kyriakos M, Greenaway GD. Tumors and tumor-like lesions of bone: imaging and pathology of specific lesions. In: Diagnosis of Bone and Joint Disorders. 4th ed. Philadelphia, Pa: WB Saunders Co;2002: 3897-919.

  7. Wang XL, De Beuckeleer LH, De Schepper AM, Van Marck E. Low-grade chondrosarcoma vs enchondroma: challenges in diagnosis and management. Eur Radiol. 2001;11(6):1054-7. [Medline].

  8. Saki N, Akhlagh SN, Mostofi NE, Ahmadi K. Chondrosarcoma of the hyoid bone: imaging, surgical, and histopathologic correlation. Laryngoscope. Jul 2008;118(7):1211-3. [Medline].

  9. Langheinrich AC, Stolle C, Kampschulte M, Lommel D, Rau WS, Bassaly B. Diagnostic Value of Ex-Vivo Three-Dimensional Micro-Computed Tomography Imaging of Primary Nonhematopoietic Human Bone Tumors: Osteosarcoma versus Chondrosarcoma. Acta Radiol. Jul 11 2008;1-8. [Medline].

  10. Murata H, Horie N, Matsui T, Akai T, Ueda H, Oshima Y, et al. Clinical usefulness of thallium-201 scintigraphy and magnetic resonance imaging in the diagnosis of chondromyxoid fibroma. Ann Nucl Med. Apr 2008;22(3):221-4. [Medline].

  11. Bauer HC, Brosjo O, Kreicbergs A, Lindholm J. Low risk of recurrence of enchondroma and low-grade chondrosarcoma in extremities. 80 patients followed for 2-25 years. Acta Orthop Scand. Jun 1995;66(3):283-8. [Medline].

  12. Walden MJ, Murphey MD, Vidal JA. Incidental enchondromas of the knee. AJR Am J Roentgenol. Jun 2008;190(6):1611-5. [Medline].

Further Reading

Related eMedicine topics:
Chondrosarcoma (from Orthopedic Surgery)
Chondroma

Related Medscape topics:
Radiology CME and News
Specialty Site Radiology
Specialty Site Oncology

Keywords

chondrosarcoma, bone tumors, primary bone tumor, bone malignancy, primary osseous neoplasms, sarcomas, chondroid, conventional chondrosarcomas, central chondrosarcoma, peripheral chondrosarcoma, enchondroma, osteochondroma, clear cell chondrosarcoma, myxoid chondrosarcoma, mesenchymal chondrosarcoma, dedifferentiated chondrosarcoma

Contributor Information and Disclosures

Author

Geoff Hide, MBBS, MRCP, FRCR, Consultant Musculoskeletal Radiologist, Department of Radiology, Freeman Hospital; Honorary Clinical Lecturer, Faculty of Medical Sciences, University of Newcastle upon Tyne
Geoff Hide, MBBS, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Medical Editor

Michael A Bruno, MD, Associate Professor, Departments of Radiology and Medicine, Pennsylvania State University College of Medicine; Director, Radiology Quality Management Services, Milton S Hershey Medical Center, Pennsylvania State University College of Medicine
Michael A Bruno, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, Association of University Radiologists, Radiological Society of North America, Society of Nuclear Medicine, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Murali Sundaram, MBBS, FRCR, FACR, Consulting Staff, Department of Diagnostic Radiology, The Cleveland Clinic Foundation
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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