eMedicine Specialties > Radiology > Musculoskeletal

Fibrous Dysplasia: Multimedia

Author: Mahesh Kumar Neelala Anand, MBBS, DNB, FRCR, Clinical Director, Consultant Radiologist, Department of Radiology, Pennine Acute Hospitals NHS Trust, Manchester, UK
Contributor Information and Disclosures

Updated: Jul 29, 2009

Multimedia

Image shows homogeneous loss of the normal trabec...Media file 1: Image shows homogeneous loss of the normal trabecular pattern in the shaft of the humerus, with a ground-glass appearance caused by fibrous dysplasia.
Image shows homogeneous loss of the normal trabec...

Image shows homogeneous loss of the normal trabecular pattern in the shaft of the humerus, with a ground-glass appearance caused by fibrous dysplasia.

Chest radiograph shows expansion of multiple ribs...Media file 2: Chest radiograph shows expansion of multiple ribs involved by fibrous dysplasia that mimics pleural masses.
Chest radiograph shows expansion of multiple ribs...

Chest radiograph shows expansion of multiple ribs involved by fibrous dysplasia that mimics pleural masses.

Axial bone-window CT scan shows a bony mass that ...Media file 3: Axial bone-window CT scan shows a bony mass that expands the ethmoidal sinuses; this finding is consistent with fibrous dysplasia. Note the relative homogeneous attenuation of the lesion.
Axial bone-window CT scan shows a bony mass that ...

Axial bone-window CT scan shows a bony mass that expands the ethmoidal sinuses; this finding is consistent with fibrous dysplasia. Note the relative homogeneous attenuation of the lesion.

Image shows focal areas of calcification in crani...Media file 4: Image shows focal areas of calcification in craniofacial fibrous dysplasia.
Image shows focal areas of calcification in crani...

Image shows focal areas of calcification in craniofacial fibrous dysplasia.

Coronal image shows craniofacial fibrous dysplasi...Media file 5: Coronal image shows craniofacial fibrous dysplasia extendingposteriorly into the sphenoidal sinus.
Coronal image shows craniofacial fibrous dysplasi...

Coronal image shows craniofacial fibrous dysplasia extendingposteriorly into the sphenoidal sinus.

Coronal CT scan shows craniofacial fibrous dyspla...Media file 6: Coronal CT scan shows craniofacial fibrous dysplasia with expansion of paranasal sinuses caused by a homogeneous mass. The inferior part of the vestibule of the nasal cavity has a soft-tissue component.
Coronal CT scan shows craniofacial fibrous dyspla...

Coronal CT scan shows craniofacial fibrous dysplasia with expansion of paranasal sinuses caused by a homogeneous mass. The inferior part of the vestibule of the nasal cavity has a soft-tissue component.

An area of low signal on T1-weighted MR scan, wit...Media file 7: An area of low signal on T1-weighted MR scan, within the proximal shaft of the right femur. Note the narrow zone of transition from lesion to normal marrow.
An area of low signal on T1-weighted MR scan, wit...

An area of low signal on T1-weighted MR scan, within the proximal shaft of the right femur. Note the narrow zone of transition from lesion to normal marrow.

T1-weighted axial MR scan showing low signal with...Media file 8: T1-weighted axial MR scan showing low signal within the shaft of right femur in a patient with fibrous dysplasia.
T1-weighted axial MR scan showing low signal with...

T1-weighted axial MR scan showing low signal within the shaft of right femur in a patient with fibrous dysplasia.

T2-weighted axial image showing a heterogeneous h...Media file 9: T2-weighted axial image showing a heterogeneous high signal within a fibrous dysplasia in the proximal shaft of the right femur.
T2-weighted axial image showing a heterogeneous h...

T2-weighted axial image showing a heterogeneous high signal within a fibrous dysplasia in the proximal shaft of the right femur.

Sagittal T2-weighted image of fibrous dysplasia l...Media file 10: Sagittal T2-weighted image of fibrous dysplasia lesion in the shaft of the femur. Note there is some degree of expansion of the bone.
Sagittal T2-weighted image of fibrous dysplasia l...

Sagittal T2-weighted image of fibrous dysplasia lesion in the shaft of the femur. Note there is some degree of expansion of the bone.

More on Fibrous Dysplasia

Overview: Fibrous Dysplasia
Imaging: Fibrous Dysplasia
Follow-up: Fibrous Dysplasia
Multimedia: Fibrous Dysplasia
References
Further Reading

References

  1. Macdonald-Jankowski D. Fibrous dysplasia: a systematic review. Dentomaxillofac Radiol. May 2009;38(4):196-215. [Medline].

  2. Harris WH, Dudley HR, Barry RJ. The natural history of fibrous dysplasia. An orthopaedic, pathological, and roentgenographic study. J Bone Joint Surg Am. Mar 1962;44-A:207-33.

  3. Leet AI, Magur E, Lee JS, et al. Fibrous dysplasia in the spine: prevalence of lesions and association with scoliosis. J Bone Joint Surg Am. Mar 2004;86-A(3):531-7.

  4. Lichenstein L, Jaffe HL. Fibrous dysplasia of bone: a condition affecting one, several or many bones, the graver cases of which may present abnormal pigmentation of skin, premature sexual development, hyperthyroidism or still other extraskeletal abnormalities. Arch Pathol. 1942;33:777.

  5. National Institutes of Health. Osteoporosis and Related Bone Disorders-National Resource Center Web site. Fast Facts on Fibrous Dysplasia page. Available at: http://www.osteo.org/default.asp. Washington, DC: National Institutes of Health;2001. [Full Text].

  6. Resnick D, Niwayama G. Diagnosis of Bone and Joint Disorders. 2nd ed. Philadelphia, Pa: WB Saunders;. 1988: 4057-70.

  7. Kruse A, Pieles U, Riener MO, Zunker Ch, Bredell MG, Grätz KW. Craniomaxillofacial fibrous dysplasia: a 10-year database 1996-2006. Br J Oral Maxillofac Surg. Jun 2009;47(4):302-5. [Medline].

  8. Mancini F, Corsi A, De Maio F, Riminucci M, Ippolito E. Scoliosis and spine involvement in fibrous dysplasia of bone. Eur Spine J. Feb 2009;18(2):196-202. [Medline].

  9. Ziadi S, Trimeche M, Mokni M, Sriha B, Khochtali H, Korbi S. [Eighteen cases of craniofacial fibrous dysplasia.]. Rev Stomatol Chir Maxillofac. Jul 15 2009;[Medline].

  10. Rahman AM, Madge SN, Billing K, Anderson PJ, Leibovitch I, Selva D, et al. Craniofacial fibrous dysplasia: clinical characteristics and long-term outcomes. Eye. Jan 30 2009;[Medline].

  11. Valentini V, Cassoni A, Marianetti TM, Terenzi V, Fadda MT, Iannetti G. Craniomaxillofacial fibrous dysplasia: conservative treatment or radical surgery? A retrospective study on 68 patients. Plast Reconstr Surg. Feb 2009;123(2):653-60. [Medline].

  12. Schwartz DT, Alpert M. The malignant transformation of fibrous dysplasia. Am J Med Sci. Jan 1964;247:1-20. [Medline].

  13. Lädermann A, Stern R, Ceroni D, De Coulon G, Taylor S, Kaelin A. Unusual radiologic presentation of monostotic fibrous dysplasia. Orthopedics. Mar 2008;31(3):282. [Medline].

  14. Bulakbasi N, Bozlar U, Karademir I, Kocaoglu M, Somuncu I. CT and MRI in the evaluation of craniospinal involvement with polyostotic fibrous dysplasia in McCune-Albright syndrome. Diagn Interv Radiol. Dec 2008;14(4):177-81. [Medline].

  15. Sood A, Raman R, Jhobta A, Dhiman DS, Seam RK. Normal technetium-99m-MDP uptake in fibrous dysplasia of the hip. Hell J Nucl Med. Jan-Apr 2009;12(1):72-3. [Medline].

  16. Bonekamp D, Jacene H, Bartelt D, Aygun N. Conversion of FDG PET activity of fibrous dysplasia of the skull late in life mimicking metastatic disease. Clin Nucl Med. Dec 2008;33(12):909-11. [Medline].

  17. Daffner RH, Kirks DR, Gehweiler JA Jr, Heaston DK. Computed tomography of fibrous dysplasia. AJR Am J Roentgenol. Nov 1982;139(5):943-8. [Medline].

  18. De Smet A, Travers H, Neff JR. Chondrosarcoma occurring in a patient with polyostotic fibrous dysplasia. Skeletal Radiol. 1981;7:197.

  19. King RM, Payne WS, Olafsson S, Unni KK. Surgical palliation of respiratory insufficiency secondary to massive exuberant polyostotic fibrous dysplasia of the ribs. Ann Thorac Surg. Feb 1985;39(2):185-7.

Keywords

fibrous dysplasia, Lichtenstein-Jaffe's disease, Lichtenstein-Jaffe disease, McCune-Albright's disease, McCune-Albright disease, fibrous osteodystrophy, osteodystrophia fibrosa, osteitis fibrosa disseminata, monostotic form, polyostotic form, craniofacial form, cherubism

Contributor Information and Disclosures

Author

Mahesh Kumar Neelala Anand, MBBS, DNB, FRCR, Clinical Director, Consultant Radiologist, Department of Radiology, Pennine Acute Hospitals NHS Trust, Manchester, UK
Mahesh Kumar Neelala Anand, MBBS, DNB, FRCR is a member of the following medical societies: British Medical Association, British Society of Interventional Radiology, Radiological Society of North America, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Medical Editor

Michael A Bruno, MD, Associate Professor, Departments of Radiology and Medicine, Pennsylvania State University College of Medicine; Director, Radiology Quality Management Services, Milton S Hershey Medical Center, Pennsylvania State University College of Medicine
Michael A Bruno, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, Association of University Radiologists, Radiological Society of North America, Society of Nuclear Medicine, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Murali Sundaram, MBBS, FRCR, FACR, Consulting Staff, Department of Diagnostic Radiology, The Cleveland Clinic Foundation
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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