eMedicine Specialties > Radiology > Musculoskeletal

Liposarcoma, Soft Tissue: Multimedia

Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Coauthor(s): Muthusamy Chandramohan, MBBS, DMRD, FRCR, Consultant Radiologist, Bradford Teaching Hospitals, UK; Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute; Fahad Ogla Alkubaidan, MBBS, SSCR, Associate Consultant, Musculoskeletal Radiology, Deputy Program Director, Residency Training Program, King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia
Contributor Information and Disclosures

Updated: Mar 12, 2008

Multimedia

A 67-year-old man presented with a slowly growing...Media file 1: A 67-year-old man presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 2-5). The patient was a nonsmoker and was not diabetic. T1-weighted, coronal magnetic resonance imaging (MRI) shows a 5-cm, lowsignal-intensity, lobulated mass in the left upper thigh.
A 67-year-old man presented with a slowly growing...

A 67-year-old man presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 2-5). The patient was a nonsmoker and was not diabetic. T1-weighted, coronal magnetic resonance imaging (MRI) shows a 5-cm, lowsignal-intensity, lobulated mass in the left upper thigh.

T2-weighted, coronal magnetic resonance imaging (...Media file 2: T2-weighted, coronal magnetic resonance imaging (MRI) scan of the left upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1 and 3-5). The image shows a highsignal-intensity, lobulated, septate mass in the region of the groin.
T2-weighted, coronal magnetic resonance imaging (...

T2-weighted, coronal magnetic resonance imaging (MRI) scan of the left upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1 and 3-5). The image shows a highsignal-intensity, lobulated, septate mass in the region of the groin.

Contrast-enhanced, axial magnetic resonance imagi...Media file 3: Contrast-enhanced, axial magnetic resonance imaging (MRI) scan of the upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-2 and 4-5). The image shows fairly intense tumor enhancement.
Contrast-enhanced, axial magnetic resonance imagi...

Contrast-enhanced, axial magnetic resonance imaging (MRI) scan of the upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-2 and 4-5). The image shows fairly intense tumor enhancement.

Short-tau inversion recovery, turbo spin-echo, ax...Media file 4: Short-tau inversion recovery, turbo spin-echo, axial magnetic resonance imaging (MRI) scan of the left upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-3 and 5). The image shows fluid signal intensity within the tumor.
Short-tau inversion recovery, turbo spin-echo, ax...

Short-tau inversion recovery, turbo spin-echo, axial magnetic resonance imaging (MRI) scan of the left upper thigh in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-3 and 5). The image shows fluid signal intensity within the tumor.

Magnetic resonance (MR) angiogram of the leg vess...Media file 5: Magnetic resonance (MR) angiogram of the leg vessels in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-4). The image shows medial displacement and compression of the left femoral artery, superficial femoral artery, and profunda by the tumor, which resulted in the claudication.
Magnetic resonance (MR) angiogram of the leg vess...

Magnetic resonance (MR) angiogram of the leg vessels in a 67-year-old man who presented with a slowly growing mass on the left side of his groin and with mild left leg claudication (same patient as in Images 1-4). The image shows medial displacement and compression of the left femoral artery, superficial femoral artery, and profunda by the tumor, which resulted in the claudication.

Moderately hypervascular tumor in the right upper...Media file 6: Moderately hypervascular tumor in the right upper thigh shows irregular, fine tumor vessels and areas of tumor stain (see also Image 7).
Moderately hypervascular tumor in the right upper...

Moderately hypervascular tumor in the right upper thigh shows irregular, fine tumor vessels and areas of tumor stain (see also Image 7).

Moderately hypervascular tumor in the right upper...Media file 7: Moderately hypervascular tumor in the right upper thigh shows irregular, fine tumor vessels and areas of tumor stain (see also Image 6).
Moderately hypervascular tumor in the right upper...

Moderately hypervascular tumor in the right upper thigh shows irregular, fine tumor vessels and areas of tumor stain (see also Image 6).

Sagittal, T1-weighted magnetic resonance imaging ...Media file 8: Sagittal, T1-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa. The image shows a lowsignal-intensity, lobulated mass in the region of the Hunter canal (same patient as in Images 9-12).
Sagittal, T1-weighted magnetic resonance imaging ...

Sagittal, T1-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa. The image shows a lowsignal-intensity, lobulated mass in the region of the Hunter canal (same patient as in Images 9-12).

Axial, T1-weighted magnetic resonance imaging (MR...Media file 9: Axial, T1-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman obtained through a palpable mass above the left popliteal fossa. The image shows a lowsignal-intensity, lobulated mass (same patient as in Images 8 and 10-12).
Axial, T1-weighted magnetic resonance imaging (MR...

Axial, T1-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman obtained through a palpable mass above the left popliteal fossa. The image shows a lowsignal-intensity, lobulated mass (same patient as in Images 8 and 10-12).

Axial, T2-weighted magnetic resonance imaging (MR...Media file 10: Axial, T2-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa (same patient as in Images 8-9 and 11-12). The image shows a highsignal-intensity, lobulated mass.
Axial, T2-weighted magnetic resonance imaging (MR...

Axial, T2-weighted magnetic resonance imaging (MRI) scan in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa (same patient as in Images 8-9 and 11-12). The image shows a highsignal-intensity, lobulated mass.

Fat-saturated magnetic resonance imaging (MRI) sc...Media file 11: Fat-saturated magnetic resonance imaging (MRI) scan through the tumor in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa (same patient as in Images 8-10 and 12). The image shows fluid signal intensity within the mass.
Fat-saturated magnetic resonance imaging (MRI) sc...

Fat-saturated magnetic resonance imaging (MRI) scan through the tumor in a 32-year-old woman presenting with a palpable mass above the left popliteal fossa (same patient as in Images 8-10 and 12). The image shows fluid signal intensity within the mass.

Ultrasonogram in a 32-year-old woman with a mass ...Media file 12: Ultrasonogram in a 32-year-old woman with a mass above the left popliteal fossa (same patient as in Images 8-11) shows a hypoechoic (but solid) mass.
Ultrasonogram in a 32-year-old woman with a mass ...

Ultrasonogram in a 32-year-old woman with a mass above the left popliteal fossa (same patient as in Images 8-11) shows a hypoechoic (but solid) mass.

A 50-year-old man presented with a 6-month histor...Media file 13: A 50-year-old man presented with a 6-month history of a dull ache over the right hypochondrium (same patient as in Image 14). An ultrasonogram (not shown) depicted a poorly defined, infiltrating, echogenic mass in the right hepatic lobe with shadowing. A nonenhanced, axial computed tomography (CT) scan shows a low fat-attenuating mass under the diaphragm; the mass displaces the liver to the left.
A 50-year-old man presented with a 6-month histor...

A 50-year-old man presented with a 6-month history of a dull ache over the right hypochondrium (same patient as in Image 14). An ultrasonogram (not shown) depicted a poorly defined, infiltrating, echogenic mass in the right hepatic lobe with shadowing. A nonenhanced, axial computed tomography (CT) scan shows a low fat-attenuating mass under the diaphragm; the mass displaces the liver to the left.

Hepatic angiogram in a 50-year-old man who presen...Media file 14: Hepatic angiogram in a 50-year-old man who presented with a 6-month history of a dull ache over the right hypochondrium (same patient as in Image 13). The image shows a hypovascular mass that displaces the liver medially. The mass was believed to represent a retroperitoneal liposarcoma; however, at laparotomy, the tumor was discovered to be intrahepatic. The histologic appearance was that of a high-grade liposarcoma infiltrating the diaphragm.
Hepatic angiogram in a 50-year-old man who presen...

Hepatic angiogram in a 50-year-old man who presented with a 6-month history of a dull ache over the right hypochondrium (same patient as in Image 13). The image shows a hypovascular mass that displaces the liver medially. The mass was believed to represent a retroperitoneal liposarcoma; however, at laparotomy, the tumor was discovered to be intrahepatic. The histologic appearance was that of a high-grade liposarcoma infiltrating the diaphragm.

A plain radiograph of a left femur demonstrates a...Media file 15: A plain radiograph of a left femur demonstrates a large, soft-tissue mass projected over the medial aspect of the thigh (arrowheads). Small areas of radiolucency (asterisk) and calcification (arrow) are shown.
A plain radiograph of a left femur demonstrates a...

A plain radiograph of a left femur demonstrates a large, soft-tissue mass projected over the medial aspect of the thigh (arrowheads). Small areas of radiolucency (asterisk) and calcification (arrow) are shown.

Magnetic resonance imaging (MRI) scans (coronal, ...Media file 16: Magnetic resonance imaging (MRI) scans (coronal, T1-weighted image and axial, T1-weighted image with fat saturation) show a soft-tissue mass of the posterior aspect of the thigh. It has a predominantly low T1 signal intensity except in its inferior portion, which has a high T1 signal intensity isointense to subcutaneous fat. Complete suppression is shown on the axial, T1-weighted image with fat saturation (asterisk).
Magnetic resonance imaging (MRI) scans (coronal, ...

Magnetic resonance imaging (MRI) scans (coronal, T1-weighted image and axial, T1-weighted image with fat saturation) show a soft-tissue mass of the posterior aspect of the thigh. It has a predominantly low T1 signal intensity except in its inferior portion, which has a high T1 signal intensity isointense to subcutaneous fat. Complete suppression is shown on the axial, T1-weighted image with fat saturation (asterisk).

Computed tomography (CT) scan of the left thigh s...Media file 17: Computed tomography (CT) scan of the left thigh shows a huge mass (arrows) with predominant fat attenuation. The central soft-tissue component (asterisk) and thick, internal septations are consistent with liposarcoma.
Computed tomography (CT) scan of the left thigh s...

Computed tomography (CT) scan of the left thigh shows a huge mass (arrows) with predominant fat attenuation. The central soft-tissue component (asterisk) and thick, internal septations are consistent with liposarcoma.

Contrast-enhanced, axial computed tomography (CT)...Media file 18: Contrast-enhanced, axial computed tomography (CT) scan of an abdomen demonstrates a huge, intra-abdominal, fatty mass with a soft-tissue component (arrow) and thick septations. The mass displaces the descending colon and the left kidney posteriorly.
Contrast-enhanced, axial computed tomography (CT)...

Contrast-enhanced, axial computed tomography (CT) scan of an abdomen demonstrates a huge, intra-abdominal, fatty mass with a soft-tissue component (arrow) and thick septations. The mass displaces the descending colon and the left kidney posteriorly.

More on Liposarcoma, Soft Tissue

Overview: Liposarcoma, Soft Tissue
Imaging: Liposarcoma, Soft Tissue
Follow-up: Liposarcoma, Soft Tissue
Multimedia: Liposarcoma, Soft Tissue
References

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Further Reading

Keywords

soft-tissue liposarcoma, soft-tissue tumors, soft-tissue neoplasms, soft-tissue lesions, mesenchymal malignancy, mesenchymal tumor, adipose-tissue tumor, soft-tissue mass, tumors of large connective tissue spaces, retroperitoneal tumors, myxoid tumors, round cell tumors, well-differentiated tumors, pleomorphic tumors

Contributor Information and Disclosures

Author

Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP, Chairman of Medical Imaging, Professor of Radiology, NGHA, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR, LRCP is a member of the following medical societies: American Institute of Ultrasound in Medicine, Radiological Society of North America, Royal College of Physicians, Royal College of Physicians and Surgeons of the United States, Royal College of Radiologists, and Royal College of Surgeons of England
Disclosure: Nothing to disclose.

Coauthor(s)

Muthusamy Chandramohan, MBBS, DMRD, FRCR, Consultant Radiologist, Bradford Teaching Hospitals, UK
Disclosure: Nothing to disclose.

Sumaira MacDonald, MBChB, PhD, MRCP, FRCR, Lecturer, Sheffield University Medical School; Endovascular Fellow, Sheffield Vascular Institute
Sumaira MacDonald, MBChB, PhD, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Fahad Ogla Alkubaidan, MBBS, SSCR, Associate Consultant, Musculoskeletal Radiology, Deputy Program Director, Residency Training Program, King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia
Disclosure: Nothing to disclose.

Medical Editor

Giuseppe Guglielmi, MD, Associate Professor of Radiology, Department of Radiology, Scientific Institute Hospital
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Murali Sundaram, MBBS, FRCR, FACR, Consulting Staff, Department of Diagnostic Radiology, The Cleveland Clinic Foundation
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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