eMedicine Specialties > Radiology > Musculoskeletal

Osteosarcoma, Classic: Multimedia

Author: Geoff Hide, MBBS, MRCP, FRCR, Consultant Musculoskeletal Radiologist, Department of Radiology, Freeman Hospital; Honorary Clinical Lecturer, Faculty of Medical Sciences, University of Newcastle upon Tyne
Contributor Information and Disclosures

Updated: Dec 4, 2008

Multimedia

Radiograph of the femur in a patient with osteosa...Media file 1: Radiograph of the femur in a patient with osteosarcoma shows a typical Codman triangle (arrow) and more diffuse, mineralized osteoid within the soft tissues adjacent to the bone.
Radiograph of the femur in a patient with osteosa...

Radiograph of the femur in a patient with osteosarcoma shows a typical Codman triangle (arrow) and more diffuse, mineralized osteoid within the soft tissues adjacent to the bone.

Lateral radiograph of the distal femur in a child...Media file 2: Lateral radiograph of the distal femur in a child with osteosarcoma involving the metaphysis and metadiaphysis. Note the abnormal texture and mild sclerosis of the distal femoral shaft; the aggressive periosteal changes, including Codman triangles (white arrow); and the large soft tissue mass (black arrow).
Lateral radiograph of the distal femur in a child...

Lateral radiograph of the distal femur in a child with osteosarcoma involving the metaphysis and metadiaphysis. Note the abnormal texture and mild sclerosis of the distal femoral shaft; the aggressive periosteal changes, including Codman triangles (white arrow); and the large soft tissue mass (black arrow).

Sagittal T1-weighted MRI (<a href="#Multimed...Media file 3: Sagittal T1-weighted MRI (see also Image 2 in the Multimedia Section). The signal intensity of the bone marrow within the distal femoral epiphysis is normal, but abnormal signal intensity is present throughout the visible shaft. The growth plate has limited extension of the tumor. Cortical destruction (arrow) and the soft tissue mass may be readily appreciated. Note that the fat deep to the quadriceps tendon has rather heterogeneous signal intensity.
Sagittal T1-weighted MRI (<a href="#Multimed...

Sagittal T1-weighted MRI (see also Image 2 in the Multimedia Section). The signal intensity of the bone marrow within the distal femoral epiphysis is normal, but abnormal signal intensity is present throughout the visible shaft. The growth plate has limited extension of the tumor. Cortical destruction (arrow) and the soft tissue mass may be readily appreciated. Note that the fat deep to the quadriceps tendon has rather heterogeneous signal intensity.

Sagittal short-tau inversion recovery (STIR) MRI ...Media file 4: Sagittal short-tau inversion recovery (STIR) MRI (see also Images 2-3 in the Multimedia Section; compare the MRI appearances with that of Image 3). Note the increased signal intensity (arrow) throughout the reactive zone within fat deep to the quadriceps tendon. Microinvasion by tumor and reactive edema cannot be differentiated in these areas.
Sagittal short-tau inversion recovery (STIR) MRI ...

Sagittal short-tau inversion recovery (STIR) MRI (see also Images 2-3 in the Multimedia Section; compare the MRI appearances with that of Image 3). Note the increased signal intensity (arrow) throughout the reactive zone within fat deep to the quadriceps tendon. Microinvasion by tumor and reactive edema cannot be differentiated in these areas.

Axial T1-weighted MRI (<a href="#Multimediamedia2...Media file 5: Axial T1-weighted MRI (see also Images 2-4 in the Multimedia Section). The abnormal medullary signal intensity (white arrow) and the soft tissue mass (black arrow) are identified.
Axial T1-weighted MRI (<a href="#Multimediamedia2...

Axial T1-weighted MRI (see also Images 2-4 in the Multimedia Section). The abnormal medullary signal intensity (white arrow) and the soft tissue mass (black arrow) are identified.

Axial short-tau inversion recovery (STIR) MRI (<a...Media file 6: Axial short-tau inversion recovery (STIR) MRI (see also Images 2-5 in the Multimedia Section). The abnormal medullary signal intensity (black arrow) and the soft tissue mass (white arrow) are identified.
Axial short-tau inversion recovery (STIR) MRI (<a...

Axial short-tau inversion recovery (STIR) MRI (see also Images 2-5 in the Multimedia Section). The abnormal medullary signal intensity (black arrow) and the soft tissue mass (white arrow) are identified.

Anteroposterior (AP) radiograph of the proximal t...Media file 7: Anteroposterior (AP) radiograph of the proximal tibia in a child with osteosarcoma involving the metaphysis. The tumor is densely sclerotic, but an area of lucency and cortical destruction is shown proximally on its lateral margin. Scalloping of the cortex is observed inferior to this area, with amorphous mineralized osteoid shown in the soft tissues (arrow). Note that the tumor appears to be superiorly confined by the growth plate.
Anteroposterior (AP) radiograph of the proximal t...

Anteroposterior (AP) radiograph of the proximal tibia in a child with osteosarcoma involving the metaphysis. The tumor is densely sclerotic, but an area of lucency and cortical destruction is shown proximally on its lateral margin. Scalloping of the cortex is observed inferior to this area, with amorphous mineralized osteoid shown in the soft tissues (arrow). Note that the tumor appears to be superiorly confined by the growth plate.

Coronal T1-weighted MRI (<a href="#Multimediamedi...Media file 8: Coronal T1-weighted MRI (see also Image 7 in the Multimedia Section). Note the abnormal signal intensity in the metaphyseal marrow and the soft tissue mass (black arrow). Early tumor extension is shown beyond the growth plate into the epiphysis (white arrows).
Coronal T1-weighted MRI (<a href="#Multimediamedi...

Coronal T1-weighted MRI (see also Image 7 in the Multimedia Section). Note the abnormal signal intensity in the metaphyseal marrow and the soft tissue mass (black arrow). Early tumor extension is shown beyond the growth plate into the epiphysis (white arrows).

Lateral radiograph of the calcaneum in an adult w...Media file 9: Lateral radiograph of the calcaneum in an adult with osteosarcoma shows a predominantly lucent lesion in the anteroinferior part of the bone and cortical destruction.
Lateral radiograph of the calcaneum in an adult w...

Lateral radiograph of the calcaneum in an adult with osteosarcoma shows a predominantly lucent lesion in the anteroinferior part of the bone and cortical destruction.

Lateral isotope bone scan (<a href="#Multimediame...Media file 10: Lateral isotope bone scan (see also Image 9 in the Multimedia Section) reveals intense uptake in the calcaneal region. The remainder of the skeleton appeared normal.
Lateral isotope bone scan (<a href="#Multimediame...

Lateral isotope bone scan (see also Image 9 in the Multimedia Section) reveals intense uptake in the calcaneal region. The remainder of the skeleton appeared normal.

Sagittal T1-weighted MRI (<a href="#Multimediamed...Media file 11: Sagittal T1-weighted MRI (see also Images 9-10 in the Multimedia Section). The true extent of the lesion within the calcaneum may be better appreciated on this image than on the radiograph. Extension into the sinus tarsi and calcaneocuboid joint is also shown.
Sagittal T1-weighted MRI (<a href="#Multimediamed...

Sagittal T1-weighted MRI (see also Images 9-10 in the Multimedia Section). The true extent of the lesion within the calcaneum may be better appreciated on this image than on the radiograph. Extension into the sinus tarsi and calcaneocuboid joint is also shown.

Anteroposterior (AP) radiograph in a patient with...Media file 12: Anteroposterior (AP) radiograph in a patient with osteosarcoma of the proximal humerus. Note the extensive soft tissue mass containing a considerable amount of mineralized osteoid.
Anteroposterior (AP) radiograph in a patient with...

Anteroposterior (AP) radiograph in a patient with osteosarcoma of the proximal humerus. Note the extensive soft tissue mass containing a considerable amount of mineralized osteoid.

Anteroposterior (AP) radiograph of the shoulder i...Media file 13: Anteroposterior (AP) radiograph of the shoulder in a patient with osteosarcoma of the scapula. Note the extensive cortical destruction, aggressive periosteal changes, and soft tissue ossification of the acromion and upper scapula.
Anteroposterior (AP) radiograph of the shoulder i...

Anteroposterior (AP) radiograph of the shoulder in a patient with osteosarcoma of the scapula. Note the extensive cortical destruction, aggressive periosteal changes, and soft tissue ossification of the acromion and upper scapula.

Lateral radiograph of the distal femur in an adul...Media file 14: Lateral radiograph of the distal femur in an adult patient with osteosarcoma appearing as a pathologic fracture.
Lateral radiograph of the distal femur in an adul...

Lateral radiograph of the distal femur in an adult patient with osteosarcoma appearing as a pathologic fracture.

More on Osteosarcoma, Classic

Overview: Osteosarcoma, Classic
Imaging: Osteosarcoma, Classic
Follow-up: Osteosarcoma, Classic
Multimedia: Osteosarcoma, Classic
References
Further Reading

References

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Further Reading


Related eMedicine topics:
Osteosarcoma (Orthopedic Surgery)
Osteosarcoma, Variants

Related Medscape topics:
Specialty Site Radiology
Specialty Site Hematology-Oncology
Radiology CME and News

Keywords

classic osteosarcoma, conventional osteosarcoma, chondroblastic osteosarcoma, osteoblastic osteosarcoma, fibroblastic osteosarcoma, high-grade intramedullary osteosarcoma

Contributor Information and Disclosures

Author

Geoff Hide, MBBS, MRCP, FRCR, Consultant Musculoskeletal Radiologist, Department of Radiology, Freeman Hospital; Honorary Clinical Lecturer, Faculty of Medical Sciences, University of Newcastle upon Tyne
Geoff Hide, MBBS, MRCP, FRCR is a member of the following medical societies: British Medical Association, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Medical Editor

David S Levey, MD, PhD, Orthopedic/Spine MRI TeleRadiologist, Radsource, LLC
David S Levey, MD, PhD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Texas Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Murali Sundaram, MBBS, FRCR, FACR, Consulting Staff, Department of Diagnostic Radiology, The Cleveland Clinic Foundation
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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