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Synovial Sarcoma: Multimedia

Author: Michael J Duh, MD, Associate Physician, Kaiser Permanente
Coauthor(s): Amilcare Gentili, MD, Clinical Professor of Radiology, University of California at San Diego; Consulting Staff, Department of Radiology, Thornton Hospital; Sulabha Masih, MD, Associate Professor of Diagnostic Radiology, University of California at Los Angeles; Consulting Staff, Department of Radiology, Section of Musculoskeletal Radiology, West Los Angeles Veterans Affairs Medical Center
Contributor Information and Disclosures

Updated: Jul 13, 2007

Multimedia

Lateral radiograph of the foot in a 60-year-old m...Media file 1: Lateral radiograph of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot. The radiograph shows a soft-tissue mass that is anterior to the talus and without obvious underlying bone erosion. Subtle faint calcifications are seen within the mass.
Lateral radiograph of the foot in a 60-year-old m...

Lateral radiograph of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot. The radiograph shows a soft-tissue mass that is anterior to the talus and without obvious underlying bone erosion. Subtle faint calcifications are seen within the mass.

Coronal T1-weighted magnetic resonance image of t...Media file 2: Coronal T1-weighted magnetic resonance image of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot (same patient as in Images 1 and 3). A rounded, soft-tissue mass is seen eroding the cortex of the superior talus. The mass is predominantly isointense relative to the muscle, with scattered areas of hyperintensity that are consistent with hemorrhage.
Coronal T1-weighted magnetic resonance image of t...

Coronal T1-weighted magnetic resonance image of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot (same patient as in Images 1 and 3). A rounded, soft-tissue mass is seen eroding the cortex of the superior talus. The mass is predominantly isointense relative to the muscle, with scattered areas of hyperintensity that are consistent with hemorrhage.

Sagittal T2-weighted magnetic resonance image of ...Media file 3: Sagittal T2-weighted magnetic resonance image of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot (same patient as in Images 1-2). The mass shows predominantly high signal intensity that is hyperintense relative to fat. Scattered areas of hypointensity probably represent calcifications.
Sagittal T2-weighted magnetic resonance image of ...

Sagittal T2-weighted magnetic resonance image of the foot in a 60-year-old man who presented with a mass on the dorsum of his left foot (same patient as in Images 1-2). The mass shows predominantly high signal intensity that is hyperintense relative to fat. Scattered areas of hypointensity probably represent calcifications.

Anteroposterior radiograph of the hip in a patien...Media file 4: Anteroposterior radiograph of the hip in a patient who presented with a mass in the region of the left hip. Opaque, masslike calcifications overlying the femoral neck and inferior pubic ramus are seen.
Anteroposterior radiograph of the hip in a patien...

Anteroposterior radiograph of the hip in a patient who presented with a mass in the region of the left hip. Opaque, masslike calcifications overlying the femoral neck and inferior pubic ramus are seen.

Computed tomography scan of the hip in a patient ...Media file 5: Computed tomography scan of the hip in a patient who presented with a mass in the region of the left hip (same patient as in Image 4). The scan was obtained through the mass and demonstrates masslike areas of calcification within the muscle density in the region of the left obturator externus muscle.
Computed tomography scan of the hip in a patient ...

Computed tomography scan of the hip in a patient who presented with a mass in the region of the left hip (same patient as in Image 4). The scan was obtained through the mass and demonstrates masslike areas of calcification within the muscle density in the region of the left obturator externus muscle.

Computed tomography scan through the right thigh....Media file 6: Computed tomography scan through the right thigh. This image demonstrates a round, noncalcified, well-circumscribed mass that displaces, rather than invades, the surrounding muscles. The mass appears to be separate from the bone.
Computed tomography scan through the right thigh....

Computed tomography scan through the right thigh. This image demonstrates a round, noncalcified, well-circumscribed mass that displaces, rather than invades, the surrounding muscles. The mass appears to be separate from the bone.

Lateral radiograph of the femur in a 45-year-old ...Media file 7: Lateral radiograph of the femur in a 45-year-old man who presented with a large, right midthigh mass. This radiograph is remarkable only for a subtle soft-tissue prominence on the anterior aspect of the thigh. No calcifications are depicted.
Lateral radiograph of the femur in a 45-year-old ...

Lateral radiograph of the femur in a 45-year-old man who presented with a large, right midthigh mass. This radiograph is remarkable only for a subtle soft-tissue prominence on the anterior aspect of the thigh. No calcifications are depicted.

Computed tomography scan of the thigh in a 45-yea...Media file 8: Computed tomography scan of the thigh in a 45-year-old man who presented with a large, right midthigh mass (same patient as in Images 7, 9-10). A well-defined mass is seen on the anterior aspect of the thigh and appears to be mostly isodense relative to the muscle, with curvilinear areas of slightly increased density. The mass appears apposed to the underlying bone.
Computed tomography scan of the thigh in a 45-yea...

Computed tomography scan of the thigh in a 45-year-old man who presented with a large, right midthigh mass (same patient as in Images 7, 9-10). A well-defined mass is seen on the anterior aspect of the thigh and appears to be mostly isodense relative to the muscle, with curvilinear areas of slightly increased density. The mass appears apposed to the underlying bone.

Axial T1-weighted magnetic resonance image of the...Media file 9: Axial T1-weighted magnetic resonance image of the thigh in a 45-year-old man who presented with a large, right midthigh mass (same patient as in Images 7-8, 10). The anterior mass is well circumscribed, with mostly homogeneous isointensity relative to the muscle. Scattered, small, hyperintense foci probably represent hemorrhage. The fat plane between the mass and the femur is preserved.
Axial T1-weighted magnetic resonance image of the...

Axial T1-weighted magnetic resonance image of the thigh in a 45-year-old man who presented with a large, right midthigh mass (same patient as in Images 7-8, 10). The anterior mass is well circumscribed, with mostly homogeneous isointensity relative to the muscle. Scattered, small, hyperintense foci probably represent hemorrhage. The fat plane between the mass and the femur is preserved.

Coronal T2-weighted magnetic resonance image of t...Media file 10: Coronal T2-weighted magnetic resonance image of the thigh in a 45-year-old man who presented with a large midthigh mass on the right (same patient as in Images 7-9). On this T2-weighted image, the mass has become markedly heterogeneous, with high signal intensity depicting cystic regions of hemorrhage and necrosis. Note that portions of the mass are hyperintense relative to the subcutaneous fat. The location of the mass is somewhat atypical because it is centered at the level of the midshaft rather than near a joint.
Coronal T2-weighted magnetic resonance image of t...

Coronal T2-weighted magnetic resonance image of the thigh in a 45-year-old man who presented with a large midthigh mass on the right (same patient as in Images 7-9). On this T2-weighted image, the mass has become markedly heterogeneous, with high signal intensity depicting cystic regions of hemorrhage and necrosis. Note that portions of the mass are hyperintense relative to the subcutaneous fat. The location of the mass is somewhat atypical because it is centered at the level of the midshaft rather than near a joint.

Sagittal T1-weighted magnetic resonance image of ...Media file 11: Sagittal T1-weighted magnetic resonance image of the thigh in a patient with a mass in the anterior left upper thigh and/or inguinal region. The image shows large areas of hemorrhage and necrosis, with intermediate signal intensity on a background of a muscle-intensity mass.
Sagittal T1-weighted magnetic resonance image of ...

Sagittal T1-weighted magnetic resonance image of the thigh in a patient with a mass in the anterior left upper thigh and/or inguinal region. The image shows large areas of hemorrhage and necrosis, with intermediate signal intensity on a background of a muscle-intensity mass.

Axial T2-weighted magnetic resonance image of the...Media file 12: Axial T2-weighted magnetic resonance image of the hip in a patient with a mass in the anterior left upper thigh and/or inguinal region (same patient as in Image 11). The mass is inseparable from the underlying femoral cortex and contains strikingly hyperintense cystic areas with irregular septa of intermediate signal intensity.
Axial T2-weighted magnetic resonance image of the...

Axial T2-weighted magnetic resonance image of the hip in a patient with a mass in the anterior left upper thigh and/or inguinal region (same patient as in Image 11). The mass is inseparable from the underlying femoral cortex and contains strikingly hyperintense cystic areas with irregular septa of intermediate signal intensity.

More on Synovial Sarcoma

Overview: Synovial Sarcoma
Imaging: Synovial Sarcoma
Follow-up: Synovial Sarcoma
Multimedia: Synovial Sarcoma
References

References

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Further Reading

Keywords

synovioma, lower extremity carcinoma, synovial cancer, cancer of the lower extremities, musculoskeletal tumor, cancer of the upper extremities, t(X;18) translocation mutation, SYT gene, SSX1 gene, SSX2 gene

Contributor Information and Disclosures

Author

Michael J Duh, MD, Associate Physician, Kaiser Permanente
Michael J Duh, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, and Radiological Society of North America
Disclosure: Nothing to disclose.

Coauthor(s)

Amilcare Gentili, MD, Clinical Professor of Radiology, University of California at San Diego; Consulting Staff, Department of Radiology, Thornton Hospital
Amilcare Gentili, MD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Sulabha Masih, MD, Associate Professor of Diagnostic Radiology, University of California at Los Angeles; Consulting Staff, Department of Radiology, Section of Musculoskeletal Radiology, West Los Angeles Veterans Affairs Medical Center
Sulabha Masih, MD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Medical Editor

David S Levey, MD, PhD, Orthopedic/Spine MRI TeleRadiologist, Radsource, LLC
David S Levey, MD, PhD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Texas Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Murali Sundaram, MBBS, FRCR, FACR, Consulting Staff, Department of Diagnostic Radiology, The Cleveland Clinic Foundation
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

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