eMedicine Specialties > Radiology > Musculoskeletal

Rheumatoid Arthritis, Hands: Multimedia

Author: Ian Y Y Tsou, MBBS, FRCR, Clinical Lecturer, Faculty of Medicine, National University of Singapore; Consulting Staff, Department of Radiology, Mount Elizabeth Medical Centre
Coauthor(s): Wilfred CG Peh, MD, MBBS, FRCP(Glasg), FRCP(Edin), FRCR, MHSM, Clinical Professor, Faculty of Medicine, National University of Singapore; Senior Consultant Radiologist, Programme Office, Singapore Health Services; Michael A Bruno, MD, Associate Professor, Departments of Radiology and Medicine, Pennsylvania State University College of Medicine; Director, Radiology Quality Management Services, Milton S Hershey Medical Center, Pennsylvania State University College of Medicine
Contributor Information and Disclosures

Updated: May 10, 2007

Multimedia

Soft-tissue swelling and early erosions in the pr...Media file 1: Soft-tissue swelling and early erosions in the proximal interphalangeal joints in a patient with rheumatoid arthritis of the hands.
Soft-tissue swelling and early erosions in the pr...

Soft-tissue swelling and early erosions in the proximal interphalangeal joints in a patient with rheumatoid arthritis of the hands.

Prominent juxta-articular osteopenia in all inter...Media file 2: Prominent juxta-articular osteopenia in all interphalangeal joints in a patient with rheumatoid arthritis of the hands.
Prominent juxta-articular osteopenia in all inter...

Prominent juxta-articular osteopenia in all interphalangeal joints in a patient with rheumatoid arthritis of the hands.

Well-defined bony erosions in the carpal bones an...Media file 3: Well-defined bony erosions in the carpal bones and metacarpal bases in a patient with rheumatoid arthritis of the hands.
Well-defined bony erosions in the carpal bones an...

Well-defined bony erosions in the carpal bones and metacarpal bases in a patient with rheumatoid arthritis of the hands.

Multiple erosions with deformity of the carpal bo...Media file 4: Multiple erosions with deformity of the carpal bones in a patient with rheumatoid arthritis of the hands.
Multiple erosions with deformity of the carpal bo...

Multiple erosions with deformity of the carpal bones in a patient with rheumatoid arthritis of the hands.

Follow-up radiograph obtained after an 18-month i...Media file 5: Follow-up radiograph obtained after an 18-month interval in a patient with rheumatoid arthritis of the hands (same patient as in Image 4). Ankylosis of the carpal bones has occurred, with enlargement of the erosions.
Follow-up radiograph obtained after an 18-month i...

Follow-up radiograph obtained after an 18-month interval in a patient with rheumatoid arthritis of the hands (same patient as in Image 4). Ankylosis of the carpal bones has occurred, with enlargement of the erosions.

Subluxation in the metacarpophalangeal joints, wi...Media file 6: Subluxation in the metacarpophalangeal joints, with ulnar deviation, in a patient with rheumatoid arthritis of the hands.
Subluxation in the metacarpophalangeal joints, wi...

Subluxation in the metacarpophalangeal joints, with ulnar deviation, in a patient with rheumatoid arthritis of the hands.

Subluxation at the third metacarpophalangeal join...Media file 7: Subluxation at the third metacarpophalangeal joint and marginal erosions at the heads of the second to fourth metacarpals in a patient with rheumatoid arthritis of the hands.
Subluxation at the third metacarpophalangeal join...

Subluxation at the third metacarpophalangeal joint and marginal erosions at the heads of the second to fourth metacarpals in a patient with rheumatoid arthritis of the hands.

Marked ankylosis of most of the carpal bones in a...Media file 8: Marked ankylosis of most of the carpal bones in a patient with rheumatoid arthritis of the hands.
Marked ankylosis of most of the carpal bones in a...

Marked ankylosis of most of the carpal bones in a patient with rheumatoid arthritis of the hands.

Partial collapse of fused carpal bones with sublu...Media file 9: Partial collapse of fused carpal bones with subluxation at the radiocarpal joint in a patient with rheumatoid arthritis of the hands.
Partial collapse of fused carpal bones with sublu...

Partial collapse of fused carpal bones with subluxation at the radiocarpal joint in a patient with rheumatoid arthritis of the hands.

Sagittal fat-saturated T2-weighted magnetic reson...Media file 10: Sagittal fat-saturated T2-weighted magnetic resonance image (MRI) scan of the ring finger shows fluid with high signal intensity around the flexor tendons resulting from tenosynovitis in a patient with rheumatoid arthritis of the hands.
Sagittal fat-saturated T2-weighted magnetic reson...

Sagittal fat-saturated T2-weighted magnetic resonance image (MRI) scan of the ring finger shows fluid with high signal intensity around the flexor tendons resulting from tenosynovitis in a patient with rheumatoid arthritis of the hands.

Coronal T1-weighted MRI shows characteristic pann...Media file 11: Coronal T1-weighted MRI shows characteristic pannus and erosive changes in the wrist in a patient with active rheumatoid arthritis. Courtesy of J. Tehranzadeh, MD, University of California at Irvine.
Coronal T1-weighted MRI shows characteristic pann...

Coronal T1-weighted MRI shows characteristic pannus and erosive changes in the wrist in a patient with active rheumatoid arthritis. Courtesy of J. Tehranzadeh, MD, University of California at Irvine.

Coronal T2-weighted spin-echo MRI shows bright er...Media file 12: Coronal T2-weighted spin-echo MRI shows bright erosive changes in a patient with rheumatoid arthritis of the hands. Courtesy of J. Tehranzadeh, University of California at Irvine.
Coronal T2-weighted spin-echo MRI shows bright er...

Coronal T2-weighted spin-echo MRI shows bright erosive changes in a patient with rheumatoid arthritis of the hands. Courtesy of J. Tehranzadeh, University of California at Irvine.

Sagittal T1-weighted MRI shows erosive changes in...Media file 13: Sagittal T1-weighted MRI shows erosive changes in the lunate, capitate, and metacarpal bases in a patient with rheumatoid arthritis of the hands. Courtesy of J. Tehranzadeh, University of California at Irvine.
Sagittal T1-weighted MRI shows erosive changes in...

Sagittal T1-weighted MRI shows erosive changes in the lunate, capitate, and metacarpal bases in a patient with rheumatoid arthritis of the hands. Courtesy of J. Tehranzadeh, University of California at Irvine.

Illustration of the scanning technique. Photograp...Media file 14: Illustration of the scanning technique. Photograph depicts the typical scanning technique with application of the Entos Probe to the volar (flexor) aspect of the third metacarpophalangeal joint. The technique allows visualization of the joint surfaces, flexor tendon, and synovial sheaths in patients with rheumatoid arthritis.
Illustration of the scanning technique. Photograp...

Illustration of the scanning technique. Photograph depicts the typical scanning technique with application of the Entos Probe to the volar (flexor) aspect of the third metacarpophalangeal joint. The technique allows visualization of the joint surfaces, flexor tendon, and synovial sheaths in patients with rheumatoid arthritis.

Amplitude color Doppler sonogram in a patient wit...Media file 15: Amplitude color Doppler sonogram in a patient with active rheumatoid arthritis. Dorsal (extensor) surface of the second metacarpophalangeal joint is imaged. Intense-amplitude Doppler color flow signal demarcates the inflamed synovium (ie, joint pannus) resulting from severe hyperemia. Solid arrows indicate the extensor tendon sheath and dorsal and volar margins. Straight open arrow indicates the synovium of the joint overlying the proximal phalanx of the second digit. Curved open arrow indicates the inflamed synovium overlying the metacarpal. The asterisk indicates a small amount of anechoic fluid in the joint space.
Amplitude color Doppler sonogram in a patient wit...

Amplitude color Doppler sonogram in a patient with active rheumatoid arthritis. Dorsal (extensor) surface of the second metacarpophalangeal joint is imaged. Intense-amplitude Doppler color flow signal demarcates the inflamed synovium (ie, joint pannus) resulting from severe hyperemia. Solid arrows indicate the extensor tendon sheath and dorsal and volar margins. Straight open arrow indicates the synovium of the joint overlying the proximal phalanx of the second digit. Curved open arrow indicates the inflamed synovium overlying the metacarpal. The asterisk indicates a small amount of anechoic fluid in the joint space.

Power Doppler image shows hyperemic blood flow in...Media file 16: Power Doppler image shows hyperemic blood flow in the flexor tendon sheath in a patient with rheumatoid arthritis of the hands.
Power Doppler image shows hyperemic blood flow in...

Power Doppler image shows hyperemic blood flow in the flexor tendon sheath in a patient with rheumatoid arthritis of the hands.

Ultrasonography-guided synovial biopsy of the sec...Media file 17: Ultrasonography-guided synovial biopsy of the second metacarpophalangeal joint of the right hand in a patient with rheumatoid arthritis of the hands. The biopsy needle is seen as a straight echogenic line on the left side of the image in an oblique orientation.
Ultrasonography-guided synovial biopsy of the sec...

Ultrasonography-guided synovial biopsy of the second metacarpophalangeal joint of the right hand in a patient with rheumatoid arthritis of the hands. The biopsy needle is seen as a straight echogenic line on the left side of the image in an oblique orientation.

More on Rheumatoid Arthritis, Hands

Overview: Rheumatoid Arthritis, Hands
Imaging: Rheumatoid Arthritis, Hands
Follow-up: Rheumatoid Arthritis, Hands
Multimedia: Rheumatoid Arthritis, Hands
References

References

  1. Newman JS, Laing TJ, McCarthy CJ, Adler RS. Power Doppler sonography of synovitis: assessment of therapeutic response--preliminary observations. Radiology. Feb 1996;198(2):582-4. [Medline].

  2. Hau M, Schultz H, Tony HP, et al. Evaluation of pannus and vascularization of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis by high-resolution ultrasound (multidimensional linear array). Arthritis Rheum. Nov 1999;42(11):2303-8. [Medline].

  3. Teh J, Stevens K, Williamson L, Leung J, McNally EG. Power Doppler ultrasound of rheumatoid synovitis: quantification of therapeutic response. Br J Radiol. Dec 2003;76(912):875-9. [Medline].

  4. Strunk J, Heinemann E, Neeck G, Schmidt KL, Lange U. A new approach to studying angiogenesis in rheumatoid arthritis by means of power Doppler ultrasonography and measurement of serum vascular endothelial growth factor. Rheumatology (Oxford). Dec 2004;43(12):1480-3. [Medline].

  5. Salaffi F, Carotti M, Manganelli P, Filippucci E, Giuseppetti GM, Grassi W. Contrast-enhanced power Doppler sonography of knee synovitis in rheumatoid arthritis: assessment of therapeutic response. Clin Rheumatol. Aug 2004;23(4):285-90. [Medline].

  6. Fiocco U, Ferro F, Vezzù M, Cozzi L, Checchetto C, Sfriso P. Rheumatoid and psoriatic knee synovitis: clinical, grey scale, and power Doppler ultrasound assessment of the response to etanercept. Ann Rheum Dis. Jun 2005;64(6):899-905. [Medline].

  7. De Flaviis L, Scaglione P, Nessi R, et al. Ultrasonography of the hand in rheumatoid arthritis. Acta Radiol. Jul-Aug 1988;29(4):457-60. [Medline].

  8. Fornage BD. Soft-tissue changes in the hand in rheumatoid arthritis: evaluation with US. Radiology. Dec 1989;173(3):735-7. [Medline].

  9. Gibbon WW. Applications of ultrasound in arthritis. Semin Musculoskelet Radiol. Dec 2004;8(4):313-28. [Medline].

  10. Gilkeson G, Polisson R, Sinclair H, et al. Early detection of carpal erosions in patients with rheumatoid arthritis: a pilot study of magnetic resonance imaging. J Rheumatol. Sep 1988;15(9):1361-6. [Medline].

  11. Grassi W, Tittarelli E, Blasetti P, et al. Finger tendon involvement in rheumatoid arthritis. Evaluation with high- frequency sonography. Arthritis Rheum. Jun 1995;38(6):786-94. [Medline].

  12. Guermazi A, Taouli B, Lynch JA, Peterfy CG. Imaging of bone erosion in rheumatoid arthritis. Semin Musculoskelet Radiol. Dec 2004;8(4):269-85. [Medline].

  13. Jevtic V, Watt I, Rozman B, et al. Contrast enhanced Gd-DTPA magnetic resonance imaging in the evaluation of rheumatoid arthritis during a clinical trial with DMARDs. A prospective two-year follow-up study on hand joints in 31 patients. Clin Exp Rheumatol. Mar-Apr 1997;15(2):151-6. [Medline].

  14. Konig H, Sieper J, Wolf KJ. Rheumatoid arthritis: evaluation of hypervascular and fibrous pannus with dynamic MR imaging enhanced with Gd-DTPA. Radiology. Aug 1990;176(2):473-7. [Medline].

  15. Naredo E, Bonilla G, Gamero F. Assessment of inflammatory activity in rheumatoid arthritis: a comparative study of clinical evaluation with grey scale and power Doppler ultrasonography. Ann Rheum Dis. Mar 2005;64(3):375-81. [Full Text].

  16. Poleksic L, Zdravkovic D, Jablanovic D, et al. Magnetic resonance imaging of bone destruction in rheumatoid arthritis: comparison with radiography. Skeletal Radiol. Nov 1993;22(8):577-80. [Medline].

  17. Reiser MF, Bongartz GP, Erlemann R, et al. Gadolinium-DTPA in rheumatoid arthritis and related diseases: first results with dynamic magnetic resonance imaging. Skeletal Radiol. 1989;18(8):591-7. [Medline].

  18. Singson RD, Zalduondo FM. Value of unenhanced spin-echo MR imaging in distinguishing between synovitis and effusion of the knee. AJR Am J Roentgenol. Sep 1992;159(3):569-71. [Medline].

  19. Sugimoto H, Takeda A, Hyodoh K. Early-stage rheumatoid arthritis: prospective study of the effectiveness of MR imaging for diagnosis. Radiology. Aug 2000;216(2):569-75. [Medline].

  20. Szkudlarek M, Court-Payen M, Strandberg C, et al. Contrast-enhanced power Doppler ultrasonography of the metacarpophalangeal joints in rheumatoid arthritis. Eur Radiol. Jan 2003;13(1):163-8. [Medline].

  21. Tehranzadeh J, Ashikyan O, Dascalos J. Advanced imaging of early rheumatoid arthritis. Radiol Clin North Am. Jan 2004;42(1):89-107. [Medline].

  22. Wakefield RJ, Kong KO, Conaghan PG, et al. The role of ultrasonography and magnetic resonance imaging in early rheumatoid arthritis. Clin Exp Rheumatol. Sep-Oct 2003;21(5 Suppl 31):S42-9. [Medline].

Further Reading

Keywords

RA, human leukocyte antigen, DR4, DRB1, joint deformity, joint fusion, metacarpophalangeal joint, MCP joint, proximal interphalangeal joint, PIP joint, thumb interphalangeal joint, IP joint, distal interphalangeal joint, DIP joint, swan-neck deformity, boutonnière deformity, button-hole deformity, inflammatory joint disease, rheumatoid nodules

Contributor Information and Disclosures

Author

Ian Y Y Tsou, MBBS, FRCR, Clinical Lecturer, Faculty of Medicine, National University of Singapore; Consulting Staff, Department of Radiology, Mount Elizabeth Medical Centre
Ian Y Y Tsou, MBBS, FRCR is a member of the following medical societies: American Roentgen Ray Society and Royal College of Radiologists
Disclosure: Nothing to disclose.

Coauthor(s)

Wilfred CG Peh, MD, MBBS, FRCP(Glasg), FRCP(Edin), FRCR, MHSM, Clinical Professor, Faculty of Medicine, National University of Singapore; Senior Consultant Radiologist, Programme Office, Singapore Health Services
Wilfred CG Peh, MD, MBBS, FRCP(Glasg), FRCP(Edin), FRCR, MHSM is a member of the following medical societies: American Roentgen Ray Society, British Institute of Radiology, International Skeletal Society, Radiological Society of North America, Royal College of Physicians, and Royal College of Radiologists
Disclosure: Nothing to disclose.

Michael A Bruno, MD, Associate Professor, Departments of Radiology and Medicine, Pennsylvania State University College of Medicine; Director, Radiology Quality Management Services, Milton S Hershey Medical Center, Pennsylvania State University College of Medicine
Michael A Bruno, MD is a member of the following medical societies: American College of Radiology, American Roentgen Ray Society, Association of University Radiologists, Radiological Society of North America, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Medical Editor

Amilcare Gentili, MD, Clinical Professor of Radiology, University of California at San Diego; Consulting Staff, Department of Radiology, Thornton Hospital
Amilcare Gentili, MD is a member of the following medical societies: American Roentgen Ray Society, Radiological Society of North America, and Society of Skeletal Radiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Lynne S Steinbach, MD, Chief of Musculoskeletal Radiology, Professor, Department of Radiology, University of California at San Francisco
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Felix S Chew, MD, MBA, EdM, Professor, Department of Radiology, Vice Chairman for Radiology Informatics, Section Head of Musculoskeletal Radiology, University of Washington
Felix S Chew, MD, MBA, EdM is a member of the following medical societies: American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.