eMedicine Specialties > Radiology > Obstetrics/Gynecology

Ectopic Pregnancy: Multimedia

Author: Douglas Bourgon, MD, Diagnostic Radiologist, Image Guided Therapeutics
Coauthor(s): Eric Outwater, MD, Professor, Department of Radiology, University of Arizona; Gregory J Balmforth, MD, Staff Physician, Department of Diagnostic Radiology, University of Arizona Medical Center
Contributor Information and Disclosures

Updated: Jul 18, 2008

Multimedia

Sagittal endovaginal sonogram of the uterus (same...Media file 1: Sagittal endovaginal sonogram of the uterus (same patient in Images 1-3). This image shows no evident intrauterine pregnancy.
Sagittal endovaginal sonogram of the uterus (same...

Sagittal endovaginal sonogram of the uterus (same patient in Images 1-3). This image shows no evident intrauterine pregnancy.

Endovaginal sonogram (same patient in <a href="#M...Media file 2: Endovaginal sonogram (same patient in Images 1-3). This image shows a coronal view of the adnexa. Hypoechoic fluid surrounds the fallopian tube.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 1-3). This image shows a coronal view of the adnexa. Hypoechoic fluid surrounds the fallopian tube.

Endovaginal sonogram (same patient in <a href="#M...Media file 3: Endovaginal sonogram (same patient in Images 1-3). This image shows the tubal ring sign as well as diffuse thickening of the fallopian tube wall with minimal surrounding free fluid.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 1-3). This image shows the tubal ring sign as well as diffuse thickening of the fallopian tube wall with minimal surrounding free fluid.

Endovaginal sonogram (same patient as in <a href=...Media file 4: Endovaginal sonogram (same patient as in Images 4-5). This image shows a coronal view of the pelvis. Moderate hypoechoic free fluid is associated with a large, heterogeneous, right adnexal mass.
Endovaginal sonogram (same patient as in <a href=...

Endovaginal sonogram (same patient as in Images 4-5). This image shows a coronal view of the pelvis. Moderate hypoechoic free fluid is associated with a large, heterogeneous, right adnexal mass.

Endovaginal sonogram (same patient as in <a href=...Media file 5: Endovaginal sonogram (same patient as in Images 4-5). This image shows a coronal view of a right adnexal mass. An ectopic embryo is present within the heterogeneous right adnexal mass. The cursors denote the crown-rump length.
Endovaginal sonogram (same patient as in <a href=...

Endovaginal sonogram (same patient as in Images 4-5). This image shows a coronal view of a right adnexal mass. An ectopic embryo is present within the heterogeneous right adnexal mass. The cursors denote the crown-rump length.

Endovaginal sonogram (same patient in <a href="#M...Media file 6: Endovaginal sonogram (same patient in Images 6-9). This image shows a sagittal view of the uterus with a pseudogestational sac. Reactive changes secondary to an ectopic pregnancy are seen as hypoechoic material within the endometrial canal, which is outlined by a single hyperechoic rim. This should be contrasted with the dual hyperechoic lines that represent the dual decidual sac, an indicator of a normal intrauterine pregnancy.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 6-9). This image shows a sagittal view of the uterus with a pseudogestational sac. Reactive changes secondary to an ectopic pregnancy are seen as hypoechoic material within the endometrial canal, which is outlined by a single hyperechoic rim. This should be contrasted with the dual hyperechoic lines that represent the dual decidual sac, an indicator of a normal intrauterine pregnancy.

Endovaginal sonogram (same patient in <a href="#M...Media file 7: Endovaginal sonogram (same patient in Images 6-9). This image shows a coronal view of the right ovary. A corpus luteum cyst mimics an ectopic pregnancy. The cursors denote a hyperechoic clot within the cyst.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 6-9). This image shows a coronal view of the right ovary. A corpus luteum cyst mimics an ectopic pregnancy. The cursors denote a hyperechoic clot within the cyst.

Endovaginal sonogram (same patient in <a href="#M...Media file 8: Endovaginal sonogram (same patient in Images 6-9). This image shows a sagittal view of the right ovary. A corpus luteum cyst mimics an ectopic pregnancy. The cursors denote a hyperechoic clot within the cyst. Note the thin rim of ovarian tissue surrounding the cyst.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 6-9). This image shows a sagittal view of the right ovary. A corpus luteum cyst mimics an ectopic pregnancy. The cursors denote a hyperechoic clot within the cyst. Note the thin rim of ovarian tissue surrounding the cyst.

Endovaginal sonogram (same patient in <a href="#M...Media file 9: Endovaginal sonogram (same patient in Images 6-9). This image shows a coronal view of the right adnexa. In this patient, the true ectopic pregnancy is identified as a large, heterogeneous adnexal mass surrounded by free fluid.
Endovaginal sonogram (same patient in <a href="#M...

Endovaginal sonogram (same patient in Images 6-9). This image shows a coronal view of the right adnexa. In this patient, the true ectopic pregnancy is identified as a large, heterogeneous adnexal mass surrounded by free fluid.

Endovaginal sonogram. This view shows a color Dop...Media file 10: Endovaginal sonogram. This view shows a color Doppler image of the adnexa with the ring-of-fire sign. Marked hyperemia is present throughout the wall of an enlarged fallopian tube.
Endovaginal sonogram. This view shows a color Dop...

Endovaginal sonogram. This view shows a color Doppler image of the adnexa with the ring-of-fire sign. Marked hyperemia is present throughout the wall of an enlarged fallopian tube.

Axial T2-weighted fast spin-echo magnetic resonan...Media file 11: Axial T2-weighted fast spin-echo magnetic resonance image of the pelvis (same patient as in Images 11-14). This image shows an abnormal fluid-containing fallopian tube (red arrow) on the right side. A simple right ovarian cyst (white arrow) is also present.
Axial T2-weighted fast spin-echo magnetic resonan...

Axial T2-weighted fast spin-echo magnetic resonance image of the pelvis (same patient as in Images 11-14). This image shows an abnormal fluid-containing fallopian tube (red arrow) on the right side. A simple right ovarian cyst (white arrow) is also present.

Coronal T2-weighted fat-saturated magnetic resona...Media file 12: Coronal T2-weighted fat-saturated magnetic resonance image of the pelvis (same patient as in Images 11-14). This image shows an abnormal fluid-containing fallopian tube (red arrow) on the right side. A simple ovarian cyst (white arrow) is also present on the right.
Coronal T2-weighted fat-saturated magnetic resona...

Coronal T2-weighted fat-saturated magnetic resonance image of the pelvis (same patient as in Images 11-14). This image shows an abnormal fluid-containing fallopian tube (red arrow) on the right side. A simple ovarian cyst (white arrow) is also present on the right.

Axial T2-weighted fast spin echo magnetic resonan...Media file 13: Axial T2-weighted fast spin echo magnetic resonance image of the pelvis (same patient as in Images 11-14). After 1 week of conservative therapy, the ectopic pregnancy in Images 11-12 ruptured. A large, mixed-signal-intensity hematoma is now present in the rectouterine pouch (noted by the H and arrows).
Axial T2-weighted fast spin echo magnetic resonan...

Axial T2-weighted fast spin echo magnetic resonance image of the pelvis (same patient as in Images 11-14). After 1 week of conservative therapy, the ectopic pregnancy in Images 11-12 ruptured. A large, mixed-signal-intensity hematoma is now present in the rectouterine pouch (noted by the H and arrows).

Axial T2-weighted gradient-echo magnetic resonanc...Media file 14: Axial T2-weighted gradient-echo magnetic resonance image of the pelvis (same patient as in Images 11-14). After 1 week of conservative therapy, the ectopic pregnancy in Images 11-12 ruptured. A large mixed-signal-intensity hematoma is now present in the rectouterine pouch (noted by the H and arrows).
Axial T2-weighted gradient-echo magnetic resonanc...

Axial T2-weighted gradient-echo magnetic resonance image of the pelvis (same patient as in Images 11-14). After 1 week of conservative therapy, the ectopic pregnancy in Images 11-12 ruptured. A large mixed-signal-intensity hematoma is now present in the rectouterine pouch (noted by the H and arrows).

More on Ectopic Pregnancy

Overview: Ectopic Pregnancy
Imaging: Ectopic Pregnancy
Follow-up: Ectopic Pregnancy
Multimedia: Ectopic Pregnancy
References
Further Reading

References

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  10. Katsikis I, Rousso D, Farmakiotis D, et al. Receiver operator characteristics and diagnostic value of progesterone and CA-125 in the prediction of ectopic and abortive intrauterine gestations. Eur J Obstet Gynecol Reprod Biol. Apr 1 2006;125(2):226-32. [Medline].

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  12. Hertzberg BS, Kliewer MA, Bowie JD. Sonographic evaluation for ectopic pregnancy: transabdominal scanning of patients with nondistended urinary bladders as a complement to transvaginal sonography. AJR Am J Roentgenol. Sep 1999;173(3):773-5. [Medline][Full Text].

  13. Outwater EK, Siegelman ES, Chiowanich P, et al. Dilated fallopian tubes: MR imaging characteristics. Radiology. Aug 1998;208(2):463-9. [Medline][Full Text].

  14. Condous GS. Ultrasound diagnosis of ectopic pregnancy. Semin Reprod Med. Mar 2007;25(2):85-91. [Medline].

  15. Hertzberg BS, Kliewer MA, Bowie JD. Adnexal ring sign and hemoperitoneum caused by hemorrhagic ovarian cyst: pitfall in the sonographic diagnosis of ectopic pregnancy. AJR Am J Roentgenol. Nov 1999;173(5):1301-2. [Medline][Full Text].

  16. Gurel S, Sarikaya B, Gurel K, Akata D. Role of sonography in the diagnosis of ectopic pregnancy. J Clin Ultrasound. Nov-Dec 2007;35(9):509-17. [Medline].

  17. Sawyer E, Jurkovic D. Ultrasonography in the diagnosis and management of abnormal early pregnancy. Clin Obstet Gynecol. Mar 2007;50(1):31-54. [Medline].

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  27. Barnhart KT, Gosman G, Ashby R, Sammel M. The medical management of ectopic pregnancy: a meta-analysis comparing "single dose" and "multidose" regimens. Obstet Gynecol. Apr 2003;101(4):778-84. [Medline].

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  31. Mueller MD, Raio L, Spoerri S, et al. Novel placental and nonplacental serum markers in ectopic versus normal intrauterine pregnancy. Fertil Steril. Apr 2004;81(4):1106-11. [Medline].

  32. Nagayama M, Watanabe Y, Okumura A, et al. Fast MR imaging in obstetrics. Radiographics. May-Jun 2002;22(3):563-80; discussion 580-2. [Medline][Full Text].

  33. Nishino M, Hayakawa K, Kawamata K, Iwasaku K, Takasu K. MRI of early unruptured ectopic pregnancy: detection of gestational sac. J Comput Assist Tomogr. Jan-Feb 2002;26(1):134-7. [Medline].

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  36. Yoden E, Imajo Y, Yamauchi H, Kohno I. Ectopic pregnancy showing interesting findings on MR imaging. AJR Am J Roentgenol. Mar 2001;176(3):818-9. [Medline][Full Text].

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Further Reading

Clinical guidelines:

Undifferentiated vaginal bleeding/abdominal pain suggestive of ectopic pregnancy clinical pathway.
Maine Medical Center, Department of Emergency Medicine - Hospital/Medical Center.  2006 Aug.  Various pagings.  NGC:005248

Medical management of ectopic pregnancy. American College of Obstetricians and Gynecologists - Medical Specialty Society.  1998 Dec (revised 2008 Jun).  7 pages.  NGC:006533

Clinical studies:

Two-Dose Methotrexate for Ectopic Pregnancy

Ectopic Pregnancy Biomarkers

Risk Factors of Ectopic Pregnancy

Evaluation of Therapeutic Strategies for Treatment of Ectopic Pregnancies (EP) and Evaluation of Subsequent Fertility

Keywords

ectopic pregnancy, ectopic gestation, extrauterine gestation, heterotopic pregnancy, metacyesis, eccyesis, interstitial ectopic, cornual ectopic, cervical ectopic, fimbrial ectopic, ovarian ectopic, ovarian pregnancy, peritoneal ectopic, tubal pregnancy, abdominal pregnancy, pelvic inflammatory disease

Contributor Information and Disclosures

Author

Douglas Bourgon, MD, Diagnostic Radiologist, Image Guided Therapeutics
Douglas Bourgon, MD is a member of the following medical societies: American College of Radiology, American Medical Association, American Roentgen Ray Society, and Radiological Society of North America
Disclosure: Nothing to disclose.

Coauthor(s)

Eric Outwater, MD, Professor, Department of Radiology, University of Arizona
Eric Outwater, MD is a member of the following medical societies: American College of Radiology, Phi Beta Kappa, and Radiological Society of North America
Disclosure: Nothing to disclose.

Gregory J Balmforth, MD, Staff Physician, Department of Diagnostic Radiology, University of Arizona Medical Center
Disclosure: Nothing to disclose.

Medical Editor

Harris L Cohen, MD, FACR, Vice Chairman/Associate Chairman (Research Activities), Director, Division of Body Imaging, Professor of Radiology, Stony Brook School of Medicine; Visiting Professor of Radiology, Johns Hopkins School of Medicine
Harris L Cohen, MD, FACR is a member of the following medical societies: American College of Radiology, American Institute of Ultrasound in Medicine, Association of Program Directors in Radiology, Radiological Society of North America, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Karen L Reuter, MD, FACR, Professor, Department of Radiology, Lahey Clinic Medical Center
Karen L Reuter, MD, FACR is a member of the following medical societies: American Association for Women Radiologists, American College of Radiology, American Institute of Ultrasound in Medicine, American Roentgen Ray Society, and Radiological Society of North America
Disclosure: Nothing to disclose.

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, The Angeles Clinic and Research Institute
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Eugene C Lin, MD, Consulting Radiologist, Virginia Mason Medical Center; Clinical Assistant Professor of Radiology, University of Washington School of Medicine
Eugene C Lin, MD is a member of the following medical societies: American College of Nuclear Medicine, American College of Radiology, Radiological Society of North America, and Society of Nuclear Medicine
Disclosure: Nothing to disclose.

 
 
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