eMedicine Specialties > Radiology > Vascular/Interventional

Arteritis, Takayasu: Follow-up

Author: Robert L Cirillo Jr, MD, MBA, Assistant Professor of Radiology, Florida State University College of Medicine; Medical Interventional Radiologist, Director/CEO, South Georgia Vascular Institute and South Georgia Laser Vein Center
Contributor Information and Disclosures

Updated: Sep 10, 2008

Intervention

Early corticosteroid therapy may lead to improvements in the clinical findings and may aid in subsidence of the active inflammatory process of Takayasu arteritis. Prednisone is usually effective in controlling the clinical symptoms of Takayasu arteritis and in controlling and decreasing the progression of active disease.7

Other medications that may be used as alternative or adjuvant therapy include cyclophosphamide and methotrexate. Methotrexate and intravenous cyclophosphamide have been used in patients who have glucocorticoid-resistant Takayasu areteritis.9,23 Each has systemic adverse effects.

Angioplasty is an accepted and successful treatment of patients with Takayasu arteritis, especially after the acute inflammatory phase has abated. Although percutaneous angioplasty is not the mainstay in the evaluation of Takayasu arteritis, it may be beneficial in assessing focal lesions and disease after the inflammatory stage. The best results have been obtained with short-segment stenoses, particularly in the iliac and renal arteries. Angioplasty is generally contraindicated during the acute phase of the disease. Stent use has been reported in a small number of cases.24,25,26,27,23

 
Acknowledgments

The author thanks his wife, Florence, for her support in allowing the time to both pursue academic endeavors and complete this project.



More on Arteritis, Takayasu

Overview: Arteritis, Takayasu
Imaging: Arteritis, Takayasu
Follow-up: Arteritis, Takayasu
Multimedia: Arteritis, Takayasu
References
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References

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Further Reading

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Keywords

Takayasu arteritis, Takayasu's arteritis, Takayasu disease, Takayasu's disease, nonspecific aortoarteritis, pulseless disease, aortic arch syndrome, granulomatous vasculitis, aortic inflammation

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Contributor Information and Disclosures

Author

Robert L Cirillo Jr, MD, MBA, Assistant Professor of Radiology, Florida State University College of Medicine; Medical Interventional Radiologist, Director/CEO, South Georgia Vascular Institute and South Georgia Laser Vein Center
Robert L Cirillo Jr, MD, MBA is a member of the following medical societies: American College of Physician Executives, Cardiovascular and Interventional Radiological Society of Europe, Society for Vascular Technology, and Society of Interventional Radiology
Disclosure: Nothing to disclose.

Medical Editor

Anthony Watkinson, MD, Professor of Interventional Radiology, The Peninsula Medical School; Consultant and Senior Lecturer, Department of Radiology, The Royal Devon and Exeter Hospital, UK
Anthony Watkinson, MD is a member of the following medical societies: Radiological Society of North America, Royal College of Radiologists, and Royal College of Surgeons of England
Disclosure: Nothing to disclose.

Pharmacy Editor

Bernard D Coombs, MB, ChB, PhD, Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand
Disclosure: Nothing to disclose.

Managing Editor

Douglas M Coldwell, MD, PhD,, Principal, Coldwell Associates. Interventional Radiologist, Jane Phillips Medical Center, Bartlesville, OK
Douglas M Coldwell, MD, PhD, is a member of the following medical societies: American Association for Cancer Research, American College of Radiology, American Heart Association, American Physical Society, American Roentgen Ray Society, Society of Cardiovascular and Interventional Radiology, Southwest Oncology Group, and Special Operations Medical Association
Disclosure: Sirtex, Inc. Consulting fee Speaking and teaching

CME Editor

Robert M Krasny, MD, Consulting Staff, Department of Radiology, Resolution Imaging Medical Corporation
Robert M Krasny, MD is a member of the following medical societies: American Roentgen Ray Society and Radiological Society of North America
Disclosure: Nothing to disclose.

Chief Editor

Kyung J Cho, MD, FACR, William Martel Professor of Radiology, Interventional Radiology Fellowship Director, University of Michigan Health System
Kyung J Cho, MD, FACR is a member of the following medical societies: American College of Radiology, American Heart Association, American Medical Association, American Roentgen Ray Society, Association of University Radiologists, and Radiological Society of North America
Disclosure: Nothing to disclose.

 
 
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