Hemorrhagic Shock Follow-up

  • Author: John Udeani, MD, FAAEM; Chief Editor: John Geibel, MD, DSc, MA   more...
 
Updated: Feb 3, 2011
 

Further Inpatient Care

  • The remainder of care is determined by the proximate course of the hemorrhagic shock.
  • Patients with hemorrhagic shock are at risk for acute tubular necrosis, acute lung injury, transfusion-related acute lung injury, infections (principally nosocomial and related to operative sites or indwelling catheters), and multiple organ dysfunction syndrome, with its attendant risk of death. Discussion of each of these entities is beyond the scope of this article.
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Inpatient & Outpatient Medications

  • Patients with hemorrhagic shock are often unable to mount an appropriate bone marrow response in the acute setting with regard to red blood cell production. Using erythropoietin (40,000 U/wk) in combination with supplemental iron and vitamin C to boost production is useful. This strategy has been used successfully to decrease red blood cell transfusions in a large multicenter trial in Canada.
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Transfer

  • In general, few indications exist to transfer a patient who is in shock to a specialized facility. Ideally, all hospitals and physicians should be prepared to initially treat and stabilize the patient with exsanguinating hemorrhage. After control of the bleeding and reversal of acute shock, patients may be transferred to facilities that can treat additional injuries.
  • The patient should be transferred by an advanced life support unit with the capability of blood transfusion en route.
  • The decision for air ambulance transport instead of ground transportation is one that involves consideration of proximity, difficulty with the ground route, time en route, weather conditions, and availability.
  • Patients may be transferred for ongoing management of the initial injury when the injury complex demands care that exceeds the resources or capabilities of the initially receiving facility. This transfer should be made from the transferring physician to the receiving physician without intermediaries.
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Complications

  • The primary complication is death.
  • The entire spectrum of organ failures may be the sequelae of resuscitated hemorrhagic shock.
  • The cascade of systemic inflammatory response syndrome (SIRS) progressing to multiple organ failure syndrome (as described by the late Roger Bone, MD) complicates the cases of approximately 30-70% of patients who present with hemorrhagic shock and survive their initial resuscitation.
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Prognosis

  • Prognosis is related to the ability to be resuscitated from shock, as well as the underlying illness or injury, not the presentation of hemorrhagic shock.
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Patient Education

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Contributor Information and Disclosures
Author

John Udeani, MD, FAAEM  Assistant Professor, Department of Emergency Medicine, Charles Drew University of Medicine and Science, University of California, Los Angeles, David Geffen School of Medicine

John Udeani, MD, FAAEM is a member of the following medical societies: American Academy of Emergency Medicine and American College of Emergency Physicians

Disclosure: Nothing to disclose.

Specialty Editor Board

Lewis J Kaplan, MD, FACS, FCCM, FCCP  Director, SICU and Surgical Critical Care Fellowship, Associate Professor, Department of Surgery, Section of Trauma, Surgical Critical Care, and Surgical Emergencies, Yale University School of Medicine

Lewis J Kaplan, MD, FACS, FCCM, FCCP is a member of the following medical societies: American Association for the Surgery of Trauma, American College of Surgeons, Association for Academic Surgery, Association for Surgical Education, Connecticut State Medical Society, Eastern Association for the Surgery of Trauma, International Trauma Anesthesia and Critical Care Society, Society for the Advancement of Blood Management, Society of Critical Care Medicine, and Surgical Infection Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Robert L Sheridan, MD  Assistant Chief of Staff, Chief of Burn Surgery, Shriners Burns Hospital; Associate Professor of Surgery, Department of Surgery, Division of Trauma and Burns, Massachusetts General Hospital and Harvard Medical School

Robert L Sheridan, MD is a member of the following medical societies: American Academy of Pediatrics, American Association for the Surgery of Trauma, American Burn Association, and American College of Surgeons

Disclosure: Nothing to disclose.

Timothy D Rice, MD  Associate Professor, Departments of Internal Medicine and Pediatrics and Adolescent Medicine, St Louis University School of Medicine

Timothy D Rice, MD is a member of the following medical societies: American Academy of Pediatrics and American College of Physicians

Disclosure: Nothing to disclose.

Chief Editor

John Geibel, MD, DSc, MA  Vice Chair and Professor, Department of Surgery, Section of Gastrointestinal Medicine, and Department of Cellular and Molecular Physiology, Yale University School of Medicine; Director, Surgical Research, Department of Surgery, Yale-New Haven Hospital

John Geibel, MD, DSc, MA is a member of the following medical societies: American Gastroenterological Association, American Physiological Society, American Society of Nephrology, Association for Academic Surgery, International Society of Nephrology, New York Academy of Sciences, and Society for Surgery of the Alimentary Tract

Disclosure: AMGEN Royalty Consulting; ARdelyx Ownership interest Board membership

References
  1. Blalock A. Principle of Surgical Care, Shock, and Other Problems. St Louis: Mosby; 1940.

  2. Levi M, Levy JH, Andersen HF, Truloff D. Safety of recombinant activated factor VII in randomized clinical trials. N Engl J Med. Nov 4 2010;363(19):1791-800. [Medline].

  3. Aledort LM. Off-label use of recombinant activated factor VII--safe or not safe?. N Engl J Med. Nov 4 2010;363(19):1853-4. [Medline].

  4. Ambrogi MC, Lucchi M, Dini P, et al. Videothoracoscopy for evaluation and treatment of hemothorax. J Cardiovasc Surg (Torino). Feb 2002;43(1):109-12. [Medline].

  5. Barber AE, Shires GT. Cell damage after shock. New Horiz. May 1996;4(2):161-7. [Medline].

  6. Brown MA, Casola G, Sirlin CB, et al. Blunt abdominal trauma: screening us in 2,693 patients. Radiology. Feb 2001;218(2):352-8. [Medline].

  7. Butler K, Winters M. Shock: beyond the "golden hour". Emergency Medicine Reports. 2003;24:345-356.

  8. Collins JA. The pathophysiology of hemorrhagic shock. Prog Clin Biol Res. 1982;108:5-29. [Medline].

  9. Dizien O, Held JP, Eyssette M, et al. [Severe cranial trauma in the rehabilitation milieu. Management in the initial phase]. Rev Infirm. Mar 1993;43(5):33-8. [Medline].

  10. Domsky MF, Wilson RF. Hemodynamic resuscitation. Crit Care Clin. Oct 1993;9(4):715-26. [Medline].

  11. Falk JL, O'Brien JF, Kerr R. Fluid resuscitation in traumatic hemorrhagic shock. Crit Care Clin. Apr 1992;8(2):323-40. [Medline].

  12. Hollenberg SM. Cardiogenic shock. Crit Care Clin. Apr 2001;17(2):391-410. [Medline].

  13. Kemp SF. Current concepts in pathophysiology, diagnosis, and management of anaphylaxis. Immunol Allergy Clin North Am. 2001;21:611-634.

  14. Ketcham EM, Cairns CB. Hemoglobin-based oxygen carriers: development and clinical potential. Ann Emerg Med. Mar 1999;33(3):326-37. [Medline].

  15. Kramer GC, Kinsky MP, Prough DS, et al. Closed-loop control of fluid therapy for treatment of hypovolemia. J Trauma. Apr 2008;64(4 Suppl):S333-41. [Medline].

  16. Krausz MM. Initial resuscitation of hemorrhagic shock. World J Emerg Surg. Apr 27 2006;1(1):14.

  17. McCunn M, Karlin A. Nonblood fluid resuscitation: more questions than answers. Anesthesiol Clin North Am. 1999;17:107-123.

  18. Orlinsky M, Shoemaker W, Reis ED, et al. Current controversies in shock and resuscitation. Surg Clin North Am. Dec 2001;81(6):1217-62, xi-xii. [Medline].

  19. Pearl RG. Treatment of shock-1998. Anesthesia and Analgesia. 1998;suppl:75-84.

  20. Peitzman AB, Billiar TR, Harbrecht BG. Hemorrhagic shock. Current Problems in Surgery. 1995;32:925-1002. [Medline].

  21. Pryor JP, Pryor RJ, Stafford PW. Initial phase of trauma management and fluid resuscitation. Trauma Reports. 2002;3:1-12.

  22. Schlag G, Krosl P, Redl H. Cardiopulmonary response of the elderly to traumatic and septic shock. Prog Clin Biol Res. 1988;264:233-42. [Medline].

  23. Shoemaker WC, Peitzman AB, Bellamy R. Resuscitation from severe hemorrhage. Crit Care Med. Feb 1996;24(2 Suppl):S12-23. [Medline].

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CT scan of a 26-year-old man after a motor vehicle crash shows a significant amount of intra-abdominal bleeding.
 
 
 
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