eMedicine Specialties > Urology > Infections and Related Inflammatory Conditions

Epididymal Tuberculosis: Follow-up

Author: J Stuart Wolf Jr, MD, FACS, David A Bloom Professor of Urology, Director of Division of Minimally Invasive Urology, Department of Urology, University of Michigan
Contributor Information and Disclosures

Updated: Nov 21, 2008

Follow-up

Further Outpatient Care

  • Patients treated for epididymal tuberculosis should be monitored for resolution of symptoms and swelling of induration, which should begin within a few weeks.
  • The urine generally clears of infectious organisms within 2 weeks.
  • Patients should engage in sexual activity only when protected by a condom because semen can be infected with mycobacterium and may transmit the disease venereally.

Complications

  • Complications of advanced tuberculous epididymitis include epididymal abscess and fistula formation.
  • Both complications are usually treated with scrotal surgery. Failure of the antituberculous regimen to achieve satisfactory local response is also treated surgically.
  • Patients may become infertile, either because of extensive duct destruction or because of obstruction of the vas deferens.

Prognosis

  • Scrotal surgery may be required, which could include removal of the epididymis and testicle.
  • The ultimate prognosis is determined by the degree of systemic illness.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • Fine-needle aspiration of the epididymis may be useful to distinguish epididymal tuberculosis from bacterial epididymo-orchitis, but, because of the risk of tumor spillage, fine-needle aspiration should be avoided if a neoplasm is suspected.
  • The typical presentation of acute tuberculous epididymitis usually prompts antibiotic therapy for presumed acute bacterial epididymo-orchitis. A more insidious onset of symptoms, although not suggestive of acute bacterial epididymo-orchitis, often prompts the same therapy because tuberculosis is usually not considered by the treating physician.
  • Because tuberculous epididymitis often goes unsuspected during management of refractory epididymo-orchitis in developed countries, the ultimate diagnosis of tuberculous epididymitis usually is made when the pathological specimen from epididymo-orchiectomy is examined.
 


More on Epididymal Tuberculosis

Overview: Epididymal Tuberculosis
Differential Diagnoses & Workup: Epididymal Tuberculosis
Treatment & Medication: Epididymal Tuberculosis
Follow-up: Epididymal Tuberculosis
References

References

  1. Madeb R, Marshall J, Nativ O, Erturk E. Epididymal tuberculosis: case report and review of the literature. Urology. Apr 2005;65(4):798. [Medline].

  2. Briceño-García EM, Gómez-Pardal A, Alvarez-Bustos G, Artero-Muñoz I, Molinero MM, Seara-Valero R, et al. Tuberculous orchiepididymitis after BCG therapy for bladder cancer. J Ultrasound Med. Jul 2007;26(7):977-9. [Medline].

  3. Salvador R, Vilana R, Bargalló X, Araque X, Nicolau C. Tuberculous epididymo-orchitis after intravesical BCG therapy for superficial bladder carcinoma: sonographic findings. J Ultrasound Med. May 2007;26(5):671-4. [Medline].

  4. Falkensammer C, Gozzi C, Hager M, Maier H, Bartsch G, Höltl L, et al. Late occurrence of bilateral tuberculous-like epididymo-orchitis after intravesical bacille Calmette-Guérin therapy for superficial bladder carcinoma. Urology. Jan 2005;65(1):175. [Medline].

  5. Garbyal RS, Gupta P, Kumar S. Diagnosis of isolated tuberculous orchitis by fine-needle aspiration cytology. Diagn Cytopathol. Oct 2006;34(10):698-700. [Medline].

  6. Sah SP, Bhadani PP, Regmi R, Tewari A, Raj GA. Fine needle aspiration cytology of tubercular epididymitis and epididymo-orchitis. Acta Cytol. May-Jun 2006;50(3):243-9. [Medline].

  7. Allen FJ, de Kock ML. Genito-urinary tuberculosis--experience with 52 urology inpatients. S Afr Med J. Dec 1993;83(12):903-7. [Medline].

  8. Angulo JC, Ramirez JC, Esteban M, Sanchez-Chapado M. Perineal fistulization of genital tuberculosis. J Urol. May 1999;161(5):1576-7. [Medline].

  9. Barisic Z, Vrsalovic-Carevic N, Milostic K, et al. Tuberculous orchiepididymitis diagnosed by nucleic acid amplification test: a case report. Int Urol Nephrol. 2003;35(2):203-5. [Medline].

  10. Chen F, Brook G, Williams G, Murphy S. Tuberculous epididymo-orchitis presenting within the setting of a sexually transmitted disease clinic. Sex Transm Dis. Mar 2004;31(3):163-5. [Medline].

  11. De Backer AI, Mortelé KJ, De Roeck J, et al. Tuberculous epididymitis associated with abdominal lymphadenopathy (2004:1b). Eur Radiol. Apr 2004;14(4):748-51. [Medline].

  12. Desmond N, Lynch M, Murphy D, Mulcahy F. Tuberculous epididymitis: a case report in an HIV seropositive male. Int J STD AIDS. May-Jun 1993;4(3):178-9. [Medline].

  13. Farer LS, Lowell AM, Meador MP. Extrapulmonary tuberculosis in the United States. Am J Epidemiol. Feb 1979;109(2):205-17. [Medline].

  14. Goodman P, Maklad NF, Verani RR, Gottlieb HE. Tuberculous abscess of the testicle in AIDS: sonographic demonstration. Urol Radiol. 1990;12(1):53-5. [Medline].

  15. Graham NM, Chaisson RE. Tuberculosis and HIV infection: epidemiology, pathogenesis, and clinical aspects. Ann Allergy. Nov 1993;71(5):421-8; quiz 428-33. [Medline].

  16. Heaton ND, Hogan B, Michell M, et al. Tuberculous epididymo-orchitis: clinical and ultrasound observations. Br J Urol. Sep 1989;64(3):305-9. [Medline].

  17. Kim SH, Pollack HM, Cho KS, et al. Tuberculous epididymitis and epididymo-orchitis: sonographic findings. J Urol. Jul 1993;150(1):81-4. [Medline].

  18. Kumar PV, Owji SM, Khezri AA. Tuberculous orchitis diagnosed by fine needle aspiration cytology. Acta Cytol. Nov-Dec 1996;40(6):1253-6. [Medline].

  19. Muttarak M, Lojanapiwat B, Chaiwun B, Wudhikarn S. Preoperative diagnosis of bilateral tuberculous epididymo-orchitis following intravesical Bacillus Calmette-Guerin therapy for superficial bladder carcinoma. Australas Radiol. Jun 2002;46(2):183-5. [Medline].

  20. Muttarak M, Peh WC, Lojanapiwat B, Chaiwun B. Tuberculous epididymitis and epididymo-orchitis: sonographic appearances. AJR Am J Roentgenol. Jun 2001;176(6):1459-66. [Medline].

  21. O'Connell HE, Russell JM, Schultz TC. Delayed epididymitis following intravesical bacillus Calmette-Guerin administration. Aust N Z J Surg. Jan 1993;63(1):70-2. [Medline].

  22. Oben FT, Wright RD, Ahaghotu CA. Tuberculous epididymitis with extensive retroperitoneal and mediastinal involvement. Urology. Jul 2004;64(1):156-8. [Medline].

  23. Ortona L, Federico G. Pulmonary and extrapulmonary tuberculosis. Rays. Jan-Mar 1998;23(1):64-77. [Medline].

  24. Petersen L, Mommsen S, Pallisgaard G. Male genitourinary tuberculosis. Report of 12 cases and review of the literature. Scand J Urol Nephrol. 1993;27(3):425-8. [Medline].

  25. Schubert GE, Haltaufderheide T, Golz R. Frequency of urogenital tuberculosis in an unselected autopsy series from 1928 to 1949 and 1976 to 1989. Eur Urol. 1992;21(3):216-23. [Medline].

  26. Small PM, Schecter GF, Goodman PC, et al. Treatment of tuberculosis in patients with advanced human immunodeficiency virus infection. N Engl J Med. Jan 31 1991;324(5):289-94. [Medline].

  27. Türkvatan A, Kelahmet E, Yazgan C, Olcer T. Sonographic findings in tuberculous epididymo-orchitis. J Clin Ultrasound. Jul-Aug 2004;32(6):302-5. [Medline].

  28. Wolf JS, McAninch JW. Tuberculous epididymo-orchitis: diagnosis by fine needle aspiration. J Urol. Apr 1991;145(4):836-8. [Medline].

  29. Yang DM, Chang MS, Oh YH, et al. Chronic tuberculous epididymitis: color Doppler US findings with histopathologic correlation. Abdom Imaging. Sep-Oct 2000;25(5):559-62. [Medline].

Further Reading

Keywords

epididymal tuberculosis, epididymal TB, tuberculous epididymitis, genital tuberculosis, genital TB, genitourinary tuberculosis, genitourinary TB, mycobacterial tuberculosis, Mycobacterium tuberculosis, MTB, granulomas, extrapulmonary tuberculosis, nonpulmonary tuberculosis, extrapulmonary TB, nonpulmonary TB, male genital tuberculosis, male genital TB

Contributor Information and Disclosures

Author

J Stuart Wolf Jr, MD, FACS, David A Bloom Professor of Urology, Director of Division of Minimally Invasive Urology, Department of Urology, University of Michigan
J Stuart Wolf Jr, MD, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, Catholic Medical Association, Endourological Society, Society for Urology and Engineering, Society of Laparoendoscopic Surgeons, Society of University Urologists, and Society of Urologic Oncology
Disclosure: Terumo Corporation Consulting fee Consulting; Omeros Corporation Consulting fee Consulting

Medical Editor

Martha K Terris, MD, FACS, Professor, Department of Surgery, Medical College of Georgia
Martha K Terris, MD, FACS is a member of the following medical societies: American Cancer Society, American College of Surgeons, American Institute of Ultrasound in Medicine, American Urological Association, New York Academy of Sciences, and Society of University Urologists
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

CME Editor

Alex J Mechaber, MD, FACP, Associate Dean for Undergraduate Medical Education, Associate Professor of Medicine, University of Miami Miller School of Medicine
Alex J Mechaber, MD, FACP is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians-American Society of Internal Medicine, and Society of General Internal Medicine
Disclosure: Nothing to disclose.

Chief Editor

Edward David Kim, MD, FACS, Professor of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center
Edward David Kim, MD, FACS is a member of the following medical societies: American College of Surgeons, American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, and Tennessee Medical Association
Disclosure: Lilly Consulting fee Consulting; Astellas Consulting fee Speaking and teaching; Indevus Consulting fee Speaking and teaching

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.