Priapism Differential Diagnoses

  • Author: Hosam S Al-Qudah, MD; Chief Editor: Edward David Kim, MD, FACS   more...
 
Updated: Jan 20, 2012
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Hosam S Al-Qudah, MD  Consultant Urologist, Department of General Surgery, Saad Specialist Hospital, Al-Khobar, Saudi Arabia

Disclosure: Nothing to disclose.

Coauthor(s)

Osama Al-Omar, MD  Chief of Urology, Warren General Hospital

Osama Al-Omar, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Urological Association, Michigan State Medical Society, National Arab American Medical Association, and Society for Fetal Urology

Disclosure: Nothing to disclose.

Monica Parraga-Marquez, MD  Consulting Staff, Department of Emergency Medicine, Metropolitan Hospital Center; Clinical Assistant Professor, Department of Emergency Medicine, New York Medical College

Monica Parraga-Marquez, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Richard A Santucci, MD, FACS  Specialist-in-Chief, Department of Urology, Detroit Medical Center; Chief of Urology, Detroit Receiving Hospital; Director, The Center for Urologic Reconstruction; Clinical Professor of Urology, Michigan State University College of Medicine

Richard A Santucci, MD, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, and Société Internationale d'Urologie (International Society of Urology)

Disclosure: Nothing to disclose.

Paul S Wahlheim, MD  Staff Physician, Department of Emergency Medicine, St Joseph's Hospital and Medical Center

Paul S Wahlheim, MD is a member of the following medical societies: American Academy of Emergency Medicine and American College of Emergency Physicians

Disclosure: Nothing to disclose.

Specialty Editor Board

Edward David Kim, MD, FACS  Professor of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center

Edward David Kim, MD, FACS is a member of the following medical societies: American College of Surgeons, American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, Sexual Medicine Society of North America, and Tennessee Medical Association

Disclosure: Lilly Consulting fee Advisor; Astellas Consulting fee Speaking and teaching; Watson Consulting fee Speaking and teaching; Allergan Consulting fee Speaking and teaching

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

J Stuart Wolf Jr, MD, FACS  The David A Bloom Professor of Urology, Director, Division of Endourology and Stone Disease, Department of Urology, University of Michigan Medical School

J Stuart Wolf Jr, MD, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, Catholic Medical Association, Endourological Society, Society for Urology and Engineering, Society of Laparoendoscopic Surgeons, Society of University Urologists, and Society of Urologic Oncology

Disclosure: Nothing to disclose.

Chief Editor

Edward David Kim, MD, FACS  Professor of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine; Consulting Staff, University of Tennessee Medical Center

Edward David Kim, MD, FACS is a member of the following medical societies: American College of Surgeons, American Society for Reproductive Medicine, American Society of Andrology, American Urological Association, Sexual Medicine Society of North America, and Tennessee Medical Association

Disclosure: Lilly Consulting fee Advisor; Astellas Consulting fee Speaking and teaching; Watson Consulting fee Speaking and teaching; Allergan Consulting fee Speaking and teaching

References
  1. Dubin J, Davis JE. Penile emergencies. Emerg Med Clin North Am. Aug 2011;29(3):485-99. [Medline].

  2. Kulmala RV, Lehtonen TA, Tammela TL. Preservation of potency after treatment for priapism. Scand J Urol Nephrol. Aug 1996;30(4):313-6. [Medline].

  3. Lieberman L, Kirby M, Ozolins L, Mosko J, Friedman J. Initial presentation of unscreened children with sickle cell disease: the Toronto experience. Pediatr Blood Cancer. Sep 2009;53(3):397-400. [Medline].

  4. Casiano H, Globerman D, Enns MW. Recurrent priapism during treatment with clozapine, quetiapine and haloperidol. J Psychopharmacol. Nov 2007;21(8):898-9. [Medline].

  5. Lin YY, Chu SJ, Tsai SH. Association between priapism and concurrent use of risperidone and Ginkgo biloba. Mayo Clin Proc. Oct 2007;82(10):1289-90. [Medline].

  6. Ruan X, Couch JP, Shah RV, Liu H, Wang F, and Chiravuri S. Priapism - A Rare Complication Following Continuous Epidural Morphine and Bupivacaine Infusion. Pain Physician. Sep 2007;10(5):707-711. [Medline].

  7. Kim KR, Shin JH, Song HY, Ko GY, Yoon HK, Sung KB, et al. Treatment of high-flow priapism with superselective transcatheter embolization in 27 patients: a multicenter study. J Vasc Interv Radiol. Oct 2007;18(10):1222-6. [Medline].

  8. Hellstrom WJ, Derosa A, Lang E. The use of transcatheter superselective embolization to treat high flow priapism (arteriocavernosal fistula) caused by straddle injury. J Urol. Sep 2007;178(3 Pt 1):1059. [Medline].

  9. American Urological Association, Inc.: 2003. Guideline on the management of priapism. Available at http://www.auanet.org/guidelines/main_reports/priapism/online.pdf.

  10. Abern MR, Levine LA. Ketoconazole and prednisone to prevent recurrent ischemic priapism. J Urol. Oct 2009;182(4):1401-6. [Medline].

  11. Mains E, Aboumarzouk O, Ahmad S, El-Mokadem I, Nabi G. A minimally invasive temporary cavernoso-saphenous shunt in the management of priapism after failed conservative treatment. Minim Invasive Ther Allied Technol. Dec 5 2011;[Medline].

  12. Agrawal DK, Jha S, Verma A, Tripathi AK, Singh BN. Priapism, complicating chronic myeloid leukemia--a case report. Indian J Cancer. Mar 1991;28(1):51-2. [Medline].

  13. Atala A, Amin M, Harty JI, Liu YK, Keeling MM. Priapism associated with asplenic state. Urology. Oct 1992;40(4):371-3. [Medline].

  14. Baba H, Furusawa N, Tanaka Y, Imura S, Tomita K. Intermittent priapism associated with lumbar spinal stenosis. Int Orthop. Jun 1994;18(3):150-3. [Medline].

  15. Banos JE, Bosch F, Farre M. Drug-induced priapism. Its aetiology, incidence and treatment. Med Toxicol Adverse Drug Exp. Jan-Feb 1989;4(1):46-58. [Medline].

  16. Baruchel S, Rees J, Bernstein ML, Goodyer P. Relief of sickle cell priapism by hydralazine. Report of a case. Am J Pediatr Hematol Oncol. Feb 1993;15(1):115-6. [Medline].

  17. Bastuba MD, Saenz de Tejada I, Dinlenc CZ, Sarazen A, Krane RJ, Goldstein I. Arterial priapism: diagnosis, treatment and long-term followup. J Urol. May 1994;151(5):1231-7. [Medline].

  18. Bochinski DJ, Deng DY, Lue TF. Management of Priapism. AUA Update Series. 2004;23:Lesson 3.

  19. Bos SD, Buys GA. Treatment of priapism with ethyl chloride spray after failed intracavernous injection with adrenaline. Br J Urol. Nov 1994;74(5):677-8. [Medline].

  20. Dogra PN, Wadhwa SN, Mehta VK. Vivax malaria causing priapism. J Assoc Physicians India. Jul 1991;39(7):571-2. [Medline].

  21. Dore F, Bonfigli S, Pardini S, Pirozzi F, Longinotti M. Priapism in thalassemia intermedia. Haematologica. Nov-Dec 1991;76(6):523. [Medline].

  22. Dutertre JP, Soutif D, Jonville AP, Cadenne M, Valat JP, Autret E. Sexual disturbances during omeprazole therapy. Lancet. Oct 19 1991;338(8773):1022. [Medline].

  23. Ekström B, Olsson AM. Priapism in patients treated with total parenteral nutrition. Br J Urol. Feb 1987;59(2):170-1. [Medline].

  24. Fernando IN, Tobias JS. Priapism in patient on tamoxifen. Lancet. Feb 25 1989;1(8635):436. [Medline].

  25. Flanagan NG, Jain A, Ridway JC. Priapism in myeloma. Clin Lab Haematol. 1987;9(2):209-10. [Medline].

  26. Fowler JE Jr, Koshy M, Strub M, Chinn SK. Priapism associated with the sickle cell hemoglobinopathies: prevalence, natural history and sequelae. J Urol. Jan 1991;145(1):65-8. [Medline].

  27. Gupta S, Moreland RB, Munarriz R, Daley J, Goldstein I, Saenz de Tejada I. Possible role of Na(+)-K(+)-ATPase in the regulation of human corpus cavernosum smooth muscle contractility by nitric oxide. Br J Pharmacol. Oct 1995;116(4):2201-6. [Medline].

  28. Hamre MR, Harmon EP, Kirkpatrick DV, Stern MJ, Humbert JR. Priapism as a complication of sickle cell disease. J Urol. Jan 1991;145(1):1-5. [Medline].

  29. Hauri D, Spycher M, Brühlmann W. Erection and priapism: a new physiopathological concept. Urol Int. 1983;38(3):138-45. [Medline].

  30. Hidalgo Ovejero AM, Garcia Mata S, Sauras Herranz MA, Maravi Petri E, Martinez Grande M. Intermittent priapism in spinal stenosis. Acta Orthop Belg. 1991;57(2):192-4. [Medline].

  31. Jiva T, Anwer S. Priapism associated with chronic cocaine abuse. Arch Intern Med. Aug 8 1994;154(15):1770. [Medline].

  32. Keoghane SR, Sullivan ME, Miller MA. The aetiology, pathogenesis and management of priapism. BJU Int. Jul 2002;90(2):149-54. [Medline].

  33. Kim N, Azadzoi KM, Goldstein I, Saenz de Tejada I. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. J Clin Invest. Jul 1991;88(1):112-8. [Medline].

  34. Lee M, Cannon B, Sharifi R. Chart for preparation of dilutions of alpha-adrenergic agonists for intracavernous use in treatment of priapism. J Urol. Apr 1995;153(4):1182-3. [Medline].

  35. Levine JF, Saenz de Tejada I, Payton TR, Goldstein I. Recurrent prolonged erections and priapism as a sequela of priapism: pathophysiology and management. J Urol. Apr 1991;145(4):764-7. [Medline].

  36. Levine LA, Guss SP. Gonadotropin-releasing hormone analogues in the treatment of sickle cell anemia-associated priapism. J Urol. Aug 1993;150(2 Pt 1):475-7. [Medline].

  37. Lue TF. Physiology of erection and pathophysiology of impotence. In: Walsh PC, Retik AB, Stamey TA, Vaughan ED, eds. Campbell's Urology. 6th ed. Philadelphia, Pa: WB Saunders; 1992:702.

  38. Lue TF. Physiology of penile erection and pathophysiology of erectile dysfunction and priapism. In: Walsh PC, Retik AB, eds. Campbell's Urology. 8th ed. Philadelphia, Pa: WB Saunders; 2002:1591-618.

  39. Melman A, Christ GJ, Hirsch MS. Anatomy and physiology of the penis. In: Bennett AH, ed. Impotence: Diagnosis and Management of Erectile Dysfunction. Philadelphia, Pa: WB Saunders; 1994:18-30.

  40. Papadopoulos I, Kelâmi A. Priapus and priapism. From mythology to medicine. Urology. Oct 1988;32(4):385-6. [Medline].

  41. Parrillo SJ, Manfrey S. Idiopathic priapism treated with inhalation of amyl nitrite. Ann Emerg Med. Apr 1983;12(4):226-7. [Medline].

  42. Ruch W, Jenny P. Priapism following testosterone administration for delayed male puberty. Am J Med. Feb 1989;86(2):256. [Medline].

  43. Saenz de Tejada I, Ware JC, Blanco R, Pittard JT, Nadig PW, Azadzoi KM, et al. Pathophysiology of prolonged penile erection associated with trazodone use. J Urol. Jan 1991;145(1):60-4. [Medline].

  44. Stackl W, Mee SL. Priapism. In: Krane RJ, Siroky MB, Firzpatrick JM, eds. Clinical Urology. Philadelphia, Pa: Lippincott, Williams & Wilkins; 1994:1245-58.

  45. Steers WD, Selby JB Jr. Use of methylene blue and selective embolization of the pudendal artery for high flow priapism refractory to medical and surgical treatments. J Urol. Nov 1991;146(5):1361-3. [Medline].

  46. Stothers L, Ritchie B. Priapism in the newborn. Can J Surg. Jun 1992;35(3):325-6. [Medline].

  47. Velek M, Stanford GK, Marco L. Priapism associated with concurrent use of thioridazine and metoclopramide. Am J Psychiatry. Jun 1987;144(6):827-8. [Medline].

  48. Vilke GM, Harrigan RA, Ufberg JW, Chan TC. Emergency evaluation and treatment of priapism. J Emerg Med. Apr 2004;26(3):325-9. [Medline].

  49. Winter CC, McDowell G. Experience with 105 patients with priapism: update review of all aspects. J Urol. Nov 1988;140(5):980-3. [Medline].

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Priapism. Corporeal relaxation causes external pressure on the emissary veins exiting the tunica albuginea, trapping blood in the penis and causing erection.
Priapism. Sexual stimulation causes the release of nitric oxide (NO) via stimulation of nonadrenergic noncholinergic neurons. NO-activated intracellular guanylate cyclase, converting guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP), causes relaxation of cavernosal arteries and increased penile blood flow, resulting in erection.
Priapism. Winter shunt placed by biopsy needle, usually under local anesthetic.
Priapism. Proximal cavernosal-spongiosum shunt (Quackel shunt) surgically connects the proximal corpora cavernosa to the corpora spongiosum.
Priapism. Proximal cavernosal-saphenous shunt (Grayhack shunt) surgically connects the proximal corpora cavernosum to the saphenous vein.
 
 
 
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