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Hyperuricosuria and Gouty Diathesis: Multimedia

Author: Bijan Shekarriz, MD, Director, Laparoscopy and Minimally Invasive Surgery, Associate Professor of Urology, Department of Urology, State University of New York Upstate Medical University
Coauthor(s): Marshall L Stoller, MD, Medical Director of Urinary Stone Center, Professor, Department of Urology, University of California at San Francisco; Brian H Eisner, MD, Instructor in Surgery, Department of Urology, Massachusetts General Hospital-Harvard Medical School; Fellow in Endourology, Department of Urology, University of California
Contributor Information and Disclosures

Updated: Jul 28, 2008

Multimedia

CT scan demonstrating right partial staghorn uric...Media file 1: CT scan demonstrating right partial staghorn uric acid calculus. Uric acid stones appear dense on CT scan and radiolucent on kidneys, ureters, and bladder (KUB) imaging (not shown).
CT scan demonstrating right partial staghorn uric...

CT scan demonstrating right partial staghorn uric acid calculus. Uric acid stones appear dense on CT scan and radiolucent on kidneys, ureters, and bladder (KUB) imaging (not shown).

Follow-up CT scan of patient in Image 1 (ie, with...Media file 2: Follow-up CT scan of patient in Image 1 (ie, with partial staghorn uric acid calculus) 1 year later. This patient was treated with oral urinary alkalinization with sodium bicarbonate. Note only a small residual fragment is present (right image).
Follow-up CT scan of patient in Image 1 (ie, with...

Follow-up CT scan of patient in Image 1 (ie, with partial staghorn uric acid calculus) 1 year later. This patient was treated with oral urinary alkalinization with sodium bicarbonate. Note only a small residual fragment is present (right image).

More on Hyperuricosuria and Gouty Diathesis

Overview: Hyperuricosuria and Gouty Diathesis
Differential Diagnoses & Workup: Hyperuricosuria and Gouty Diathesis
Treatment & Medication: Hyperuricosuria and Gouty Diathesis
Follow-up: Hyperuricosuria and Gouty Diathesis
Multimedia: Hyperuricosuria and Gouty Diathesis
References
Further Reading

References

  1. Sakhaee K, Maalouf NM. Metabolic syndrome and uric acid nephrolithiasis. Semin Nephrol. Mar 2008;28(2):174-80. [Medline].

  2. Asplin JR. Uric acid stones. Semin Nephrol. Sep 1996;16(5):412-24. [Medline].

  3. Bernardo NO, Smith AD. Chemolysis of urinary calculi. Urol Clin North Am. May 2000;27(2):355-65. [Medline].

  4. Cameron MA, Sakhaee K. Uric acid nephrolithiasis. Urol Clin North Am. Aug 2007;34(3):335-46. [Medline].

  5. Coe FL, Kavalach AG. Hypercalciuria and hyperuricosuria in patients with calcium nephrolithiasis. N Engl J Med. Dec 19 1974;291(25):1344-50. [Medline].

  6. Low RK, Stoller ML. Uric acid-related nephrolithiasis. Urol Clin North Am. Feb 1997;24(1):135-48. [Medline].

  7. Moe OW, Abate N, Sakhaee K. Pathophysiology of uric acid nephrolithiasis. Endocrinol Metab Clin North Am. Dec 2002;31(4):895-914. [Medline].

  8. Pak CY. Medical management of urinary stone disease. Nephron Clin Pract. 2004;98(2):c49-53. [Medline].

  9. Pak CY, Moe OW, Sakhaee K, Peterson RD, Poindexter JR. Physicochemical metabolic characteristics for calcium oxalate stone formation in patients with gouty diathesis. J Urol. May 2005;173(5):1606-9. [Medline].

  10. Pak CY, Poindexter JR, Peterson RD, Koska J, Sakhaee K. Biochemical distinction between hyperuricosuric calcium urolithiasis and gouty diathesis. Urology. Nov 2002;60(5):789-94. [Medline].

  11. Pak CY, Sakhaee K, Moe O, Preminger GM, Poindexter JR, Peterson RD, et al. Biochemical profile of stone-forming patients with diabetes mellitus. Urology. Mar 2003;61(3):523-7. [Medline].

  12. Shekarriz B, Stoller ML. Uric acid nephrolithiasis: current concepts and controversies. J Urol. Oct 2002;168(4 Pt 1):1307-14. [Medline].

  13. Steele TH. Hyperuricemic nephropathies. Nephron. 1999;81 Suppl 1:45-9. [Medline].

  14. Stoller ML. Gout and stones or stones and gout?. J Urol. Nov 1995;154(5):1670. [Medline].

Further Reading

For additional information, See Medscape's Stone Disease Resource Center.

Keywords

hyperuricosuria, gouty diathesis, uric acid stones, nephrolithiasis, hyperuricemia, gouty arthritis, urolithiasis, uric acid calculi, purine, purine-rich food, endogenous uric acid overproduction, urinary stones, primary gout, gout, Lesch-Nyhan syndrome, myeloproliferative disease

Contributor Information and Disclosures

Author

Bijan Shekarriz, MD, Director, Laparoscopy and Minimally Invasive Surgery, Associate Professor of Urology, Department of Urology, State University of New York Upstate Medical University
Bijan Shekarriz, MD is a member of the following medical societies: American Urological Association and Endourological Society
Disclosure: Nothing to disclose.

Coauthor(s)

Marshall L Stoller, MD, Medical Director of Urinary Stone Center, Professor, Department of Urology, University of California at San Francisco
Marshall L Stoller, MD is a member of the following medical societies: American Urological Association
Disclosure: Nothing to disclose.

Brian H Eisner, MD, Instructor in Surgery, Department of Urology, Massachusetts General Hospital-Harvard Medical School; Fellow in Endourology, Department of Urology, University of California
Brian H Eisner, MD is a member of the following medical societies: American Urological Association and Endourological Society
Disclosure: Nothing to disclose.

Medical Editor

Allen Donald Seftel, MD, Professor, Department of Urology, Case School of Medicine
Allen Donald Seftel, MD is a member of the following medical societies: Ohio State Medical Association
Disclosure: lilly Consulting fee Consulting; sanofi-aventis Consulting fee Consulting; auxilium Consulting fee Consulting; solvay Consulting fee Consulting; plethora Grant/research funds clinical trial; indevus Consulting fee Consulting; nature publishing  journal editor

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

CME Editor

J Stuart Wolf Jr, MD, FACS, David A Bloom Professor of Urology, Director of Division of Minimally Invasive Urology, Department of Urology, University of Michigan
J Stuart Wolf Jr, MD, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, Catholic Medical Association, Endourological Society, Society for Urology and Engineering, Society of Laparoendoscopic Surgeons, Society of University Urologists, and Society of Urologic Oncology
Disclosure: Terumo Corporation Consulting fee Consulting; Gyrus-ACMI Honoraria Speaking and teaching

Chief Editor

Bradley Fields Schwartz, DO, FACS, Professor of Urology, Director, Center for Laparoscopy and Endourology, Department of Surgery, Southern Illinois University School of Medicine
Bradley Fields Schwartz, DO, FACS is a member of the following medical societies: American College of Surgeons, American Urological Association, Association of Military Osteopathic Physicians and Surgeons, Endourological Society, Society of Laparoendoscopic Surgeons, and Society of University Urologists
Disclosure: Nothing to disclose.

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