Nonbacterial Prostatitis Clinical Presentation
- Author: Sunil K Ahuja, MD; Chief Editor: Edward David Kim, MD, FACS more...
History
Patients with abacterial prostatitis/chronic pelvic pain syndrome (CPPS; category III in the 1995 National Institutes of Health prostatitis classification system) have the same symptom complex as those with chronic bacterial prostatitis. The chief symptom reported by patients with abacterial prostatitis/CPPS is pain. Genitourinary symptoms include perineal, penile tip, testicular, rectal, lower abdominal, or back pain.
Patients can also have irritative or obstructive urologic symptoms such as frequency, urgency, dysuria, decreased force of the urinary stream, nocturia, and incontinence. Other symptoms are a clear urethral discharge, ejaculatory pain, hematospermia, and sexual dysfunction.
Many patients with abacterial prostatitis have emotional strife and some psychological difficulties (ie, socially, sexually, or both). Patients should be questioned with regard to their overall social adjustment. Stress level is important because stress is responsible for increased tension of the pelvic floor and the internal urinary sphincter, resulting in the symptoms of prostatitis.
Physical Examination
In most cases, physical examination findings are nonspecific. Many patients have normal findings, others may have an exquisitely sensitive prostate or other pelvic trigger points on internal and external perianal examination, and still others may have an enlarged, boggy prostate.
Krieger JN, Nyberg L, Nickel JC. NIH consensus definition and classification of prostatitis. JAMA. Jul 21 1999;282(3):236-7. [Medline].
Litwin MS, McNaughton-Collins M, Fowler FJ Jr, Nickel JC, Calhoun EA, Pontari MA, et al. The National Institutes of Health chronic prostatitis symptom index: development and validation of a new outcome measure. Chronic Prostatitis Collaborative Research Network. J Urol. Aug 1999;162(2):369-75. [Medline].
Sandhu JS. Use of empiric antibiotics in the setting of an increased prostate specific antigen: con. J Urol. Jul 2011;186(1):18-9. [Medline].
Loeb S. Use of empiric antibiotics in the setting of an increased prostate specific antigen: pro. J Urol. Jul 2011;186(1):17-9. [Medline].
Weidner W. Treating chronic prostatitis: antibiotics no, alpha-blockers maybe. Ann Intern Med. Oct 19 2004;141(8):639-40. [Medline].
Forrest JB, Schmidt S. Interstitial cystitis, chronic nonbacterial prostatitis and chronic pelvic pain syndrome in men: a common and frequently identical clinical entity. J Urol. Dec 2004;172(6 Pt 2):2561-2. [Medline].
Collins MM, Stafford RS, O'Leary MP, Barry MJ. How common is prostatitis? A national survey of physician visits. J Urol. Apr 1998;159(4):1224-8. [Medline].
Nickel JC, Downey J, Hunter D, Clark J. Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health chronic prostatitis symptom index. J Urol. Mar 2001;165(3):842-5. [Medline].
Dalhoff A, Shalit I. Immunomodulatory effects of quinolones. Lancet Infect Dis. Jun 2003;3(6):359-71. [Medline].
Shoskes DA, Nickel JC, Rackley RR, Pontari MA. Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. Prostate Cancer Prostatic Dis. 2009;12(2):177-83. [Medline].
Anderson R, Wise D, Sawyer T, Nathanson BH. Safety and effectiveness of an internal pelvic myofascial trigger point wand for urologic chronic pelvic pain syndrome. Clin J Pain. Nov-Dec 2011;27(9):764-8. [Medline].
Barbalias GA, Nikiforidis G, Liatsikos EN. Alpha-blockers for the treatment of chronic prostatitis in combination with antibiotics. J Urol. Mar 1998;159(3):883-7. [Medline].
Kaplan SA, Volpe MA, Te AE. A prospective, 1-year trial using saw palmetto versus finasteride in the treatment of category III prostatitis/chronic pelvic pain syndrome. J Urol. Jan 2004;171(1):284-8. [Medline].
Schneider H, Ludwig M, Horstmann A, et al. The efficacy of cernilton in patients with chronic pelvic pain syndrome (CP/CPPS) type NIH III: a randomized prospective, double blind, placebo controlled study. J Urol. 2006;175(suppl);34:Abstract 105.
Nickel JC, Sorensen R. Transurethral microwave thermotherapy for nonbacterial prostatitis: a randomized double-blind sham controlled study using new prostatitis specific assessment questionnaires. J Urol. Jun 1996;155(6):1950-4; discussion 1954-5. [Medline].
Bassotti G, Whitehead WE. Biofeedback, relaxation training, and cognitive behaviour modification as treatments for lower functional gastrointestinal disorders. QJM. Aug 1997;90(8):545-50. [Medline].
Kaplan SA, Santarosa RP, D'Alisera PM, Fay BJ, Ikeguchi EF, Hendricks J, et al. Pseudodyssynergia (contraction of the external sphincter during voiding) misdiagnosed as chronic nonbacterial prostatitis and the role of biofeedback as a therapeutic option. J Urol. Jun 1997;157(6):2234-7. [Medline].
Chen R, Nickel JC. Acupuncture ameliorates symptoms in men with chronic prostatitis/chronic pelvic pain syndrome. Urology. Jun 2003;61(6):1156-9; discussion 1159. [Medline].
Anderson RU, Wise D, Sawyer T, Chan C. Integration of myofascial trigger point release and paradoxical relaxation training treatment of chronic pelvic pain in men. J Urol. Jul 2005;174(1):155-60. [Medline].

