eMedicine Specialties > Emergency Medicine > Cardiovascular
Thrombophlebitis, Superficial: Follow-up
Updated: Sep 28, 2009
Follow-up
Patients should follow-up with their primary care physician or vascular surgeon in 2-3 days to ensure that the disease process is improving.
Complications
- Extension into deep venous system
- Conversion to suppurative thrombophlebitis
- Septicemia
- Septic emboli
- Persistence of nodule
Prognosis
- The prognosis for superficial thrombophlebitis is generally good.
Patient Education
For excellent patient education resources, visit eMedicine's Circulatory Problems Center. Also, see eMedicine's patient education articles Varicose Veins, Blood Clot in the Legs, and Phlebitis.
Miscellaneous
Medicolegal Pitfalls
- Patients who present with clinical evidence of superficial phlebitis often have deep system involvement that is clinically occult. Those who lack deep system involvement often progress to develop deep vein thrombosis (DVT) over time. The incidence of fatal PE in these patients is not insignificant. Any chest symptoms, no matter how minor, should be considered extremely worrisome in a patient with superficial thrombophlebitis, as pulmonary embolism (PE) is extremely common and can be difficult to diagnose.
- Phlebitis that has progressed to involve any other deep veins (anterior or posterior tibial veins, proximal peroneal vein, popliteal vein, or femoral vein at any level) is a life-threatening condition that must not be confused with superficial venous thrombophlebitis.
- The principal deep vein of the thigh often is referred to incorrectly as the "superficial femoral vein." Do not be misled by this nomenclature. A thrombus in the superficial femoral vein is the most serious type of DVT.
- A small number of often-repeated mistakes in diagnosis and treatment are responsible for a large proportion of the bad outcomes with serious legal repercussions.
- Failure to pursue a definitive workup, attempting instead to diagnose superficial thrombophlebitis and to rule out DVT on clinical grounds that are known to be unreliable.
- Failure to warn the patient that superficial phlebitis can progress to the deep veins and that any change in symptoms warrants immediate reevaluation.
- Failure to begin a workup for pulmonary embolism when a patient has chest symptoms in the presence of leg symptoms
- Failure to start anticoagulation immediately upon the diagnosis of DVT or at suspicion of pulmonary embolism.
Special Concerns
- Venous thrombophlebitis and PE are common during all trimesters of pregnancy and for 6-12 weeks after delivery.
- Superficial varicosities and superficial phlebitis are common during pregnancy, and associated DVT is also common because of a pregnancy-related reduction in intrinsic plasminogen activator activity.
- The diagnostic approach should be exactly the same in a pregnant patient as in a nonpregnant one.
- Duplex scanning is safe in pregnancy.
- If indicated, a nuclear perfusion lung scan may be performed safely in pregnancy.
- If indicated, heparin may be used in pregnancy.
- If indicated, fibrinolytics may be used in pregnancy.
- Failure to treat the mother properly is the most common cause of fetal demise.
The authors and editors of eMedicine gratefully acknowledge the contributions of previous authors, Craig F Feied, MD, and Jonathan A Handler, MD, to the development and writing of this article.
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| References |
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References
Verlato F, Zucchetta P, Prandoni P, et al. An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh. J Vasc Surg. Dec 1999;30(6):1113-5. [Medline].
Wichers IM, Di Nisio M, Buller HR, Middeldorp S. Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review. Haematologica. May 2005;90(5):672-7. [Medline].
Rosendaal FR, Helmerhorst FM, Vandenbroucke JP. Oral contraceptives, hormone replacement therapy and thrombosis. Thromb Haemost. Jul 2001;86(1):112-23. [Medline].
Kim J, Richards S, Kent PJ. Clinical examination of varicose veins--a validation study. Ann R Coll Surg Engl. May 2000;82(3):171-5. [Medline].
Gillet JL, Ffrench P, Hanss M, Allaert FA, Chleir F. [Predictive value of D-dimer assay in superficial thrombophlebitis of the lower limbs]. J Mal Vasc. Apr 2007;32(2):90-5. [Medline].
Bergqvist D, Jaroszewski H. Deep vein thrombosis in patients with superficial thrombophlebitis of the leg. Br Med J (Clin Res Ed). Mar 8 1986;292(6521):658-9. [Medline].
Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev. Apr 18 2007;CD004982. [Medline].
Quenet S, Laporte S, Decousus H, Leizorovicz A, Epinat M, Mismetti P. Factors predictive of venous thrombotic complications in patients with isolated superficial vein thrombosis. J Vasc Surg. Nov 2003;38(5):944-9. [Medline].
Ascher E, Hanson JN, Salles-Cunha S, Hingorani A. Lesser saphenous vein thrombophlebitis: its natural history and implications for management. Vasc Endovascular Surg. Nov-Dec 2003;37(6):421-7. [Medline].
de Godoy JM, Braile DM. Protein S deficiency in repetitive superficial thrombophlebitis. Clin Appl Thromb Hemost. Jan 2003;9(1):61-2. [Medline].
De Maeseneer MG. Superficial thrombophlebitis of the lower limb: practical recommendations for diagnosis and treatment. Acta Chir Belg. Apr 2005;105(2):145-7. [Medline].
Feied CF. Pulmonary chest pain, cor pulmonale and pulmonary embolism. In: Gibler, Aufderheide, eds. Emergency Cardiac Care. Vol 1. ed. Mosby-Year Book; 1994:243-303.
Feied CF. Pulmonary embolism. In: Rosen P, Barkin RM, eds. Emergency Medicine Principles and Practice. 4th ed. Mosby-Year Book; 1998:3.
Feied CF. Peripheral venous disease. In: Rosen P, Barkin RM, eds. Emergency Medicine Principles and Practice. 4th ed. Mosby-Year Book; 1998:3.
Schonauer V, Kyrle PA, Weltermann A, et al. Superficial thrombophlebitis and risk for recurrent venous thromboembolism. J Vasc Surg. Apr 2003;37(4):834-8. [Medline].
Unno N, Mitsuoka H, Uchiyama T, et al. Superficial thrombophlebitis of the lower limbs in patients with varicose veins. Surg Today. 2002;32(5):397-401. [Medline].
Further Reading
Keywords
superficial thrombophlebitis, superficial thrombophlebitis causes, superficial thrombophlebitis treatment, superficial venous thrombosis, superficial vein thrombophlebitis, blood clot, deep vein thrombosis, DVT, pulmonary embolism, phlebitis, deep vein thrombophlebitis, superficial phlebitis
Follow-up: Thrombophlebitis, Superficial