Further Inpatient Care
- Unstable patients with thoracic aortic aneurysm (TAA) usually require medical or surgical ICU admission for careful hemodynamic monitoring.
- Patients who are symptomatic require admission, as do those in whom a final diagnosis is uncertain.
- Some patients with complicating conditions, such as Marfan syndrome or another cardiovascular disease, may require admission for medical stabilization and for more urgent surgical repair, even if they are asymptomatic at presentation.
- Indications for surgical repair include the following:[4]
- Rupture
- Acute dissection (ascending requires urgent intervention, whereas descending is managed medically or surgically, if vascular complications arise)
- Symptomatic states, including pain, mediastinal organ compression, or aortic insufficiency severe enough to cause CHF or a dilated hypokinetic left ventricle
- Rapid aneurysm growth rate
- Absolute size (5.5 cm for ascending aortic aneurysm, 6.0 cm for descending aortic aneurysm; in patients with Marfan syndrome, 5.0 cm for ascending aortic aneurysm, 6.0 cm for descending aortic aneurysm)
- Surgical and other interventional options for TAA repair include the following:[3]
- Open approaches using cardiopulmonary bypass, hypothermia, and grafting
- Endovascular stent grafting may be an option when TAA is limited to the descending aorta.
- Complications of repair include paraplegia, renal failure, and intraoperative mortality.
Transfer
- Patients with TAA who are symptomatic should only be transferred via advanced life support (ALS) system if the sending facility is unable to provide appropriate operative care.
Complications
- Complications of thoracic aortic aneurysm include the following:
- Rupture of the TAA into the mediastinum, pleural space, trachea, or esophagus
- Dissection
- Aortic insufficiency
- Congestive heart failure
Prognosis
- In a series of 370 patients with TAA, survival at 1, 5, and 10 years were found to be 88%, 69%, and 56%, respectively.[5]
Patient Education
- For patient education resources, see the Circulatory Problems Center, as well as Aortic Aneurysm.
Isselbacher EM. Thoracic and abdominal aortic aneurysms. Circulation. Feb 15 2005;111(6):816-28. [Medline].
Clouse WD, Hallett JW Jr, Schaff HV. Improved prognosis of thoracic aortic aneurysms: a population-based study. JAMA. Dec 9 1998;280(22):1926-9. [Medline].
Ince H, Nienaber CA. Etiology, pathogenesis and management of thoracic aortic aneurysm. Nat Clin Pract Cardiovasc Med. Aug 2007;4(8):418-27. [Medline].
Coady MA, Rizzo JA, Elefteriades JA. Developing surgical intervention criteria for thoracic aortic aneurysms. Cardiol Clin. Nov 1999;17(4):827-39. [Medline].
Coady MA, Rizzo JA, Goldstein LJ, Elefteriades JA. Natural history, pathogenesis, and etiology of thoracic aortic aneurysms and dissections. Cardiol Clin. Nov 1999;17(4):615-35; vii. [Medline].
Barbant SD, Eisenberg MJ, Schiller NB. The diagnostic value of imaging techniques for aortic dissection. Am Heart J. Aug 1992;124(2):541-3. [Medline].
Bickerstaff LK, Pairolero PC, Hollier LH, et al. Thoracic aortic aneurysms: a population-based study. Surgery. Dec 1982;92(6):1103-8. [Medline].
Crawford ES, Cohen ES. Aortic aneurysm: a multifocal disease. Presidential address. Arch Surg. Nov 1982;117(11):1393-400. [Medline].
Dapunt OE, Galla JD, Sadeghi AM, et al. The natural history of thoracic aortic aneurysms. J Thorac Cardiovasc Surg. May 1994;107(5):1323-32; discussion 1332-3. [Medline].
Fuster V, Andrews P. Medical treatment of the aorta. I. Cardiol Clin. Nov 1999;17(4):697-715, viii. [Medline].
Glade GJ, Vahl AC, Wisselink W, et al. Mid-term survival and costs of treatment of patients with descending thoracic aortic aneurysms; endovascular vs. open repair: a case-control study. Eur J Vasc Endovasc Surg. Jan 2005;29(1):28-34. [Medline].
Guo DC, Papke CL, He R, Milewicz DM. Pathogenesis of thoracic and abdominal aortic aneurysms. Ann N Y Acad Sci. Nov 2006;1085:339-52. [Medline].
Leurs LJ, Bell R, Degrieck Y, et al. Endovascular treatment of thoracic aortic diseases: combined experience from the EUROSTAR and United Kingdom Thoracic Endograft registries. J Vasc Surg. Oct 2004;40(4):670-9; discussion 679-80. [Medline].
Pressler V, McNamara JJ. Aneurysm of the thoracic aorta. Review of 260 cases. J Thorac Cardiovasc Surg. Jan 1985;89(1):50-4. [Medline].
Safi HJ, Miller CC. Thoracic vasculature. In: Townsend CM, Beauchamp DR, Evers MB, et al, eds. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 16th ed. Philadelphia, Pa: WB Saunders Co; 2001.

