Hidradenitis Suppurativa in Emergency Medicine Clinical Presentation
- Author: Diana Fite, MD, FACEP; Chief Editor: Rick Kulkarni, MD more...
History
The most common presentation of hidradenitis suppurativa is that of painful, tender, firm, nodular lesions under the arms.
- The nodules may open and drain pus spontaneously. Nodules will heal slowly, with or without drainage, over 10-30 days.
- In typical cases, nodules recur at least several times yearly.
- In severe cases, the patient may suffer a constant succession of new lesions forming as soon as old lesions heal.
- Remissions may last months or years.
Physical
- The patient may present in considerable pain, with multiple red, hard, raised nodules in areas where apocrine glands are concentrated.
- Affected areas may include the axillae, periareolar, intermammary zones, pubic area, infraumbilical midline, gluteal folds, genitofemoral areas (top of the thighs in genital area), and the perianal region.
- As suppuration progresses, surrounding cellulitis may be present. Chronic recurrences result in palpable thick sinus tracts under the skin, which may turn into draining fistulas.
- The patient may present with a chronic condition in which the multiple nodules have coalesced and are surrounded by a fibrous reaction. This results in scarred and unsightly appearance of the area.
- Hidradenitis suppurativa may resemble recurrent bacterial folliculitis and furunculosis.
Causes
- A genetic predisposition to hidradenitis suppurativa likely exists, with one study noting that 38% of patients had a relative with hidradenitis.[5]
- Excessive perspiration, often observed in athletes and the obese, may contribute to clogging of the apocrine glands.
- Disease activity may be related to stress and to cigarette smoking.
- Hidradenitis may be observed as a primary condition without any obvious cause, but it may be observed in association with the following conditions:
- Crohn disease
- Irritable bowel syndrome
- Down syndrome
- Certain forms of arthritis
- Graves disease or Hashimoto thyroiditis
- Sjögren syndrome
- Herpes simplex
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