Further Inpatient Care
- In general, patients with urticaria can be cared for on an outpatient basis unless their urticaria is severe and does not respond to antihistamine therapy or if they progress to laryngeal angioedema and/or anaphylactic shock, or have comorbidities that require inpatient therapy.
Further Outpatient Care
- Most patients with urticaria can be treated at home on H1 antihistamines (ie, diphenhydramine 50 mg q6h or hydroxyzine 50 mg q6h for 24-48 h) or, in refractory cases, use a combination of H1 and H2 antihistamines plus oral glucocorticoids.
- If the patient has angioedema that is treated successfully in the ED, the patient should be sent home with an EpiPen prescription and told to keep it with him or her at all times and to use it if swelling of the lips, tongue, face develops or if his or her voice acutely become hoarse.
- Consultation with or referral to a dermatologist, allergist, immunologist, or rheumatologist may be appropriate in cases of suspected urticarial vasculitis and in cases of chronic or recurrent urticaria.
Deterrence/Prevention
- Patients with urticaria should avoid any medication, food, or other allergen that has precipitated urticaria or other serious allergic reaction previously.
Prognosis
- The prognosis in acute urticaria is excellent, with most cases resolving within 1-4 days.
- The prognosis in chronic urticaria is more guarded and depends upon the comorbid disease causing the urticaria as well as the response to therapy.
Patient Education
- Education regarding avoidance of the suspected offending allergen is essential.
- For excellent patient education resources, visit eMedicine's Allergy Center and Skin, Hair, and Nails Center. Also, see eMedicine's patient education article Hives and Angioedema.
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