Epiglottitis Differential Diagnoses

  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Pamela L Dyne, MD   more...
 
Updated: Jul 14, 2011
 
 

Diagnostic Considerations

Clinician familiarity with epiglottitis has lessened in the post-Hib vaccination era, which may lead to less acumen in the diagnosis of this potentially deadly disorder. Efforts toward continued diligence in promptly making this diagnosis are therefore warranted, particularly in the adult patient, for whom epiglottitis has many possible causes other than Haemophilus influenzae type b.[10]

Depending on the clinical setting, it may be risky to send the patient off-unit for radiologic studies, and direct visualization of the epiglottis may precipitate respiratory obstruction. Rapid diagnosis may depend on the examination and those tests that can be performed quickly at the bedside.

Other conditions to consider in the evaluation of acute epiglottitis include the following:

  • Acute angioedema
  • Airway obstruction
  • Bacterial laryngotracheobronchitis
  • Caustic ingestion
  • Thermal injury from liquids or hot air (burns)
  • Foreign body aspiration
  • Laryngeal diphtheria
  • Laryngitis
  • Laryngotracheal bronchopneumonitis
  • Peritonsillar abscess
  • Retropharyngeal abscess
  • Sepsis

See also Pediatric Epiglottitis and Emergent Management of Pediatric Epiglottitis.

Differential Diagnoses

Proceed to Workup
 
 
Contributor Information and Disclosures
Author

Sandra G Gompf, MD, FACP, FIDSA  Associate Professor of Infectious Diseases and International Medicine, University of South Florida College of Medicine; Chief, Infectious Diseases Section, Director, Occupational Health and Infection Control Programs, James A Haley Veterans Hospital

Sandra G Gompf, MD, FACP, FIDSA is a member of the following medical societies: American College of Physicians and Infectious Diseases Society of America

Disclosure: Nothing to disclose.

Coauthor(s)

Jeffrey Glenn Bowman, MD, MS  Consulting Staff, Highfield MRI

Disclosure: Nothing to disclose.

Specialty Editor Board

Debra Slapper, MD  Consulting Staff, Department of Emergency Medicine, St Anthony's Hospital

Debra Slapper, MD is a member of the following medical societies: American Academy of Emergency Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Chief Editor

Pamela L Dyne, MD  Professor of Clinical Medicine/Emergency Medicine, University of California, Los Angeles, David Geffen School of Medicine; Attending Physician, Department of Emergency Medicine, Olive View-UCLA Medical Center

Pamela L Dyne, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

References
  1. Young LS, Price CS. Complicated adult epiglottitis due to methicillin-resistant Staphylococcus aureus. Am J Otolaryngol. Nov-Dec 2007;28(6):441-3. [Medline].

  2. Kavanagh KR, Batti JS. Traumatic epiglottitis after foreign body ingestion. Int J Pediatr Otorhinolaryngol. Jun 2008;72(6):901-3. [Medline].

  3. Wallenborn PA 3rd, Postma DS. Radiation recall supraglottitis. A hazard in head and neck chemotherapy. Arch Otolaryngol. Sep 1984;110(9):614-7. [Medline].

  4. Berg S, Trollfors B, Nylén O, Hugosson S, Prellner K, Carenfelt C. Incidence, aetiology, and prognosis of acute epiglottitis in children and adults in Sweden. Scand J Infect Dis. 1996;28(3):261-4. [Medline].

  5. Guldfred LA, Lyhne D, Becker BC. Acute epiglottitis: epidemiology, clinical presentation, management and outcome. J Laryngol Otol. Aug 2008;122(8):818-23. [Medline].

  6. Chan KO, Pang YT, Tan KK. Acute epiglottitis in the tropics: is it an adult disease?. J Laryngol Otol. Sep 2001;115(9):715-8. [Medline].

  7. Faden H. The dramatic change in the epidemiology of pediatric epiglottitis. Pediatr Emerg Care. Jun 2006;22(6):443-4. [Medline].

  8. Katori H, Tsukuda M. Acute epiglottitis: analysis of factors associated with airway intervention. J Laryngol Otol. Dec 2005;119(12):967-72. [Medline].

  9. Ehara H. Tenderness over the hyoid bone can indicate epiglottitis in adults. J Am Board Fam Med. Sep-Oct 2006;19(5):517-20. [Medline].

  10. Mathoera RB, Wever PC, van Dorsten FR, Balter SG, de Jager CP. Epiglottitis in the adult patient. Neth J Med. Oct 2008;66(9):373-7. [Medline].

  11. Ames WA, Ward VM, Tranter RM, Street M. Adult epiglottitis: an under-recognized, life-threatening condition. Br J Anaesth. Nov 2000;85(5):795-7. [Medline].

  12. Chandradeva K, Palin C, Ghosh SM, Pinches SC. Percutaneous transtracheal jet ventilation as a guide to tracheal intubation in severe upper airway obstruction from supraglottic oedema. Br J Anaesth. May 2005;94(5):683-6. [Medline].

  13. Hung TY, Li S, Chen PS, et al. Bedside ultrasonography as a safe and effective tool to diagnose acute epiglottitis. Am J Emerg Med. Mar 2011;29(3):359.e1-3. [Medline].

  14. Yong MG, Choo MJ, Yum CS, Cho SB, Shin SO, Lee DW, et al. Radiologic laryngeal parameters in acute supraglottitis in Korean adults. Yonsei Med J. Aug 2001;42(4):367-70. [Medline].

  15. Ducic Y, Hébert PC, MacLachlan L, Neufeld K, Lamothe A. Description and evaluation of the vallecula sign: a new radiologic sign in the diagnosis of adult epiglottitis. Ann Emerg Med. Jul 1997;30(1):1-6. [Medline].

  16. Werner SL, Jones RA, Emerman CL. Sonographic assessment of the epiglottis. Acad Emerg Med. Dec 2004;11(12):1358-60. [Medline].

  17. Prasad A, Singh M, Chan VW. Ultrasound imaging of the airway. Can J Anaesth. Nov 2009;56(11):868-9; author reply 869-70. [Medline].

  18. Kim SG, Lee JH, Park DJ, et al. Efficacy of spinal needle aspiration for epiglottic abscess in 90 patients with acute epiglottitis. Acta Otolaryngol. Jul 2009;129(7):760-7. [Medline].

  19. Ito K, Chitose H, Koganemaru M. Four cases of acute epiglottitis with a peritonsillar abscess. Auris Nasus Larynx. Apr 2011;38(2):284-8. [Medline].

  20. [Guideline] Centers for Disease Control and Prevention. Update: recommendations from the Advisory Committee on Immunization Practices (ACIP) regarding administration of combination MMRV vaccine. MMWR Morb Mortal Wkly Rep. Mar 14 2008;57(10):258-60. [Medline].

  21. [Guideline] Kroger AT, Atkinson WL, Marcuse EK, Pickering LK. General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. Dec 1 2006;55:1-48. [Medline].

Previous
Next
 
Soft-tissue lateral neck radiograph reveals edema of epiglottis consistent with acute epiglottitis.
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.