Hypothyroidism and Myxedema Coma in Emergency Medicine Differential Diagnoses
- Author: Erik D Schraga, MD; Chief Editor: Rick Kulkarni, MD more...
Differential Diagnoses
- Congestive Heart Failure and Pulmonary Edema
- Depression and Suicide
- Encephalopathy, Hepatic
- Hypothermia
- Shock, Septic
[Guideline] Screening for congenital hypothyroidism: US Preventive Services Task Force reaffirmation recommendation. Ann Fam Med. Mar-Apr 2008;6(2):166. [Medline].
Beynon J, Akhtar S, Kearney T. Predictors of outcome in myxoedema coma. Crit Care. 2008;12(1):111. [Medline].
[Best Evidence] Teng W, Shan Z, Teng X, Guan H, et. al. Effect of iodine intake on thyroid diseases in China. N Eng J Med. Jun 2006;354(26):2783-2793. [Medline].
Hamnvik OP, Larsen PR, Marqusee E. Thyroid dysfunction from antineoplastic agents. J Natl Cancer Inst. Nov 2 2011;103(21):1572-87. [Medline]. [Full Text].
Lee CH, Wira CR. Severe angioedema in myxedema coma: a difficult airway in a rare endocrine emergency. Am J Emerg Med. Oct 2009;27(8):1021.e1-2. [Medline].
Sanda S, Newfield RS. A child with pericardial effusion and cardiac tamponade due to previously unrecognized hypothyroidism. J Natl Med Assoc. Dec 2007;99(12):1411-3. [Medline].
Ragland G. Hypothyroidism and myxedema coma. In: Tintinalli JE, Krome RL, et al, eds. Emergency Medicine: A Comprehensive Study Guide. 4th ed. New York, NY: McGraw-Hill; 1996:964-67.
Unuane D, Tournaye H, Velkeniers B, Poppe K. Endocrine disorders & female infertility. Best Pract Res Clin Endocrinol Metab. Dec 2011;25(6):861-73. [Medline].
Flynn RW, MacDonald TM, Morris AD. The thyroid epidemiology, audit, and research study: thyroid dysfunction in the general population. J Clin Endocrinol Metab. Aug 2004;89(8):3879-84. [Medline].
Franklyn JA. The management of hyperthyroidism. N Engl J Med. Jun 16 1994;330(24):1731-8. [Medline].
Hehrmann R. [Coma in myxedema--a rare complication of hypothyroidism. Possible iatrogenic factors should be taken into account]. Fortschr Med. Dec 10 1996;114(34):474-8. [Medline].
Kinuya S, Michigishi T, Tonami N, et al. Reversible cerebral hypoperfusion observed with Tc-99m HMPAO SPECT in reversible dementia caused by hypothyroidism. Clin Nucl Med. Sep 1999;24(9):666-8. [Medline].
Menendez CE, Rivlin RS. Thyrotoxic crisis and myxedema coma. Med Clin North Am. Nov 1973;(6):1463-70. [Medline].
Rimar D, Kruzel-Davila E, Dori G, Baron E, Bitterman H. Hyperammonemic coma--barking up the wrong tree. J Gen Intern Med. Apr 2007;22(4):549-52. [Medline].
Roberts CG, Ladenson PW. Hypothyroidism. Lancet. Mar 6 2004;363(9411):793-803. [Medline].
Smith SA. Commonly asked questions about thyroid function. Mayo Clin Proc. Jun 1995;70(6):573-7. [Medline].
Ragland E, Urbanic RC, Harwood-Nuss AL, et al, eds. Thyroid Emergencies. 1996. Philadelphia, Pa: Lippincott-Raven Pub; 736-41.
Tunbridge WM, Evered DC, Hall R, et al. The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol (Oxf). Dec 1977;7(6):481-93. [Medline].
Vanderpump MP, Tunbridge WM, French JM, et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol (Oxf). Jul 1995;43(1):55-68. [Medline].
Wang C, Crapo LM. The epidemiology of thyroid disease and implications for screening. Endocrinol Metab Clin North Amer. 1997;26(1):189-218. [Medline].
Wartofsky L, Ingbar SH. Diseases of the thyroid. In: Wilson JD, Braunwald E, et al, eds. Harrison's Principles of Internal Medicine. 1991:1692-1712.
Wogan JM. Endocrine disorders. In: Rosen P, Barkin RM, et al, eds. Emergency Medicine: Concepts and Clinical Practice. 1992:2242-59.
Yamamoto T, Fukuyama J, Fujiyoshi A. Factors associated with mortality of myxedema coma: report of eight cases and literature survey. Thyroid. Dec 1999;9(12):1167-74. [Medline].

