eMedicine Specialties > Emergency Medicine > Environmental
Hymenoptera Stings: Follow-up
Updated: Apr 9, 2009
Follow-up
Further Inpatient Care
- Consider further inpatient care for all patients with life-threatening reactions.
- Observe for sufficient duration to ensure symptoms do not rebound after initial treatment. Rebound phenomena may occur up to 12 hours after sting.
- Respiratory and circulatory support may be needed if secondary organ damage has occurred.
Further Outpatient Care
- Refer all patients with generalized reactions for allergy testing and desensitization, if indicated.
- Provide means to self-administer epinephrine and diphenhydramine to all patients with generalized reactions, and advise them to wear medic alert bracelets.
- Continue treatment with steroids in the ED for 3-5 days.
- Continue administering antihistamines for at least 24 hours continuous dosing.
- Cool sting sites for 12 hours.
- Keep extremities with stings elevated for 12 hours when development of edema may present difficulties.
Deterrence/Prevention
- Avoiding stings is vitally important for persons who are hypersensitive. Whenever these patients are out of doors, they should adhere to the following suggestions:
- Avoid using perfumes or hygiene products that include perfumes as these may attract flying Hymenoptera.
- Avoid wearing bright colors.
- Avoid known hive or nest locations.
- Do not use noisy equipment such as lawn mowers, edgers, or blowers within 50 yards of beehives or 150 yards of Africanized bee colonies.
- Do not flail arms when confronted by bees or wasps because smashing one often incites others to sting.
Complications
- Sting sites may become infected. Infection is more common in fire ant stings because they frequently are multiple; stings vesiculate and then ulcerate, leaving pruritic open wounds.
- Rebound anaphylaxis may occur in patients with generalized reactions as antihistamine and alpha-agonist levels subside after treatment.
- Anaphylaxis may occur in susceptible patients from exposure to other insect-related material, including honey and apiotherapy.
- Serum-sickness-type reactions may occur up to 14 days after a sting.
- Myocardial infarction, renal failure, DIC, and cerebral edema may occur after a bee sting.
- One case report documents transient inferior ST-segment elevation consistent with myocardial ischemia after a single wasp sting in a 58-year-old man.3
- In a retrospective analysis of medical records from 1985-2007, 7 of 45 pediatric patients were noted to have developed acute renal failure after a wasp sting.4
- Peripheral nerve block may occur if sting is near the path of a nerve.
Prognosis
- Most stings resolve with no residual complaints.
- Large local reactions do not predispose patients to generalized reactions in the future.
- Less severe generalized reactions precede most fatal reactions.
Patient Education
- Educate all patients on how to avoid stings.
- For excellent patient education resources, visit eMedicine's Bee and Wasp Stings Center, Environmental Exposures and Injuries Center, Allergy Center, and Allergic Reaction and Anaphylactic Shock Center. Also, see eMedicine's patient education articles Bee and Wasp Stings and Severe Allergic Reaction (Anaphylactic Shock).
- For related information, see Medscape's Allergy Resource Center.
Miscellaneous
Medicolegal Pitfalls
- Failure to remove stinger may produce infection or granulomatous reaction.
- Failure to observe patient after treating a generalized reaction may result in unobserved rebound.
- Failure to provide means of self-treatment in those with demonstrated tendency to generalized reactions may result in unnecessary future reactions. Refer these patients to an allergist for assessment.
Special Concerns
- Infants are likely to sustain numerous fire ant stings, and they do not refrain from scratching open wounds, increasing the frequency of secondary infection. Some authorities recommend prophylactic antibiotics for children with more than 30 fire ant stings.
More on Hymenoptera Stings |
| Overview: Hymenoptera Stings |
| Differential Diagnoses & Workup: Hymenoptera Stings |
| Treatment & Medication: Hymenoptera Stings |
Follow-up: Hymenoptera Stings |
| Multimedia: Hymenoptera Stings |
| References |
| Further Reading |
| « Previous Page | Next Page » |
References
Rhoades RB, Stafford CT, James FK Jr. Survey of fatal anaphylactic reactions to imported fire ant stings. Report of the Fire Ant Subcommittee of the American Academy of Allergy and Immunology. J Allergy Clin Immunol. Aug 1989;84(2):159-62. [Medline].
Visscher PK, Vetter RS, Camazine S. Removing bee stings. Lancet. Aug 3 1996;348(9023):301-2. [Medline].
Rekik S, Andrieu S, Aboukhoudir F, Barnay P, Quaino G, Pansieri M, et al. ST Elevation Myocardial Infarction with No Structural Lesions after a Wasp Sting. J Emerg Med. Mar 26 2009;[Medline].
Vachvanichsanong P, Dissaneewate P. Acute renal failure following wasp sting in children. Eur J Pediatr. Jan 16 2009;[Medline].
Agarwal V, Singh R, Chauhan S. Parkinsonism following a honeybee sting. Indian J Med Sci. Jan 2006;60(1):24-5. [Medline].
Agarwal V, Singh R, Chauhan S, D'Cruz S, Thakur R. Parkinsonism following a honeybee sting. Indian J Med Sci. Jan 2006;60(1):24-5. [Medline].
Agostinucci W, Cardoni AA, Rosenberg P. Effect of papain of bee venom toxicity. Toxicon. 1981;19(6):851-5. [Medline].
Ariue BK. Multiple Africanized bee stings in a child. Pediatrics. Jul 1994;94(1):115-7. [Medline].
Awai LE, Mekori YA. Insect sting anaphylaxis and beta-adrenergic blockade: a relative contraindication. Ann Allergy. Jul 1984;53(1):48-9. [Medline].
Betten DP, Richardson WH, Tong TC. Massive honey bee envenomation-induced rhabdomyolysis in an adolescent. Pediatrics. Jan 2006;117(1):231-5. [Medline].
Charpin D, Birnbaum J, Vervloet D. Epidemiology of hymenoptera allergy. Clin Exp Allergy. Nov 1994;24(11):1010-5. [Medline].
Chen CJ, Richardson CD. Bee sting-induced ocular changes. Ann Ophthalmol. Oct 1986;18(10):285-6. [Medline].
Cohen SG, Bianchine PJ. Hymenoptera, hypersensitivity, and history: a prologue to current day concepts and practices in the diagnosis, treatment, and prevention of insect sting allergy. Ann Allergy Asthma Immunol. Mar 1995;74(3):198-217; quiz 217-21. [Medline].
Davis K. Africanized honey bees. 1997.
De Soto H, Turk P. Cimetidine in anaphylactic shock refractory to standard therapy. Anesth Analg. Aug 1989;69(2):264-5. [Medline].
Fitzgerald KT, Flood AA. Hymenoptera stings. Clin Tech Small Anim Pract. Nov 2006;21(4):194-204. [Medline].
Freye HB, Ehrlich B. Acute myocardial infarction following hymenoptera envenomation. Allergy Proc. Mar-Apr 1989;10(2):119-26. [Medline].
Goldstein NP, Rucker CW, Klass DW. Encephalopathy and papilledema after bee sting. JAMA. 1964;188:1083-1084. [Medline].
Hay SM, Hay FA, Austwick DH. Case report. Bee sting brachial block. Arch Emerg Med. Dec 1992;9(4):369-72. [Medline].
Hiran S, Pande TK, Pani S, Gupta R, Vishwanathan KA. Rhabdomyolysis due to multiple honey bee stings. Postgrad Med J. Dec 1994;70(830):937. [Medline].
Hur W, Ahn SK, Lee SH, Kang WH. Cutaneous reaction induced by retained bee stinger. J Dermatol. Dec 1991;18(12):736-9. [Medline].
Janik JE, Wania-Galicia L, Kalauokalani D. Bee stings--a remedy for postherpetic neuralgia? A case report. Reg Anesth Pain Med. Nov-Dec 2007;32(6):533-5. [Medline].
Karamloo F, Schmid-Grendelmeier P, Kussebi F. Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes. Eur J Immunol. Nov 2005;35(11):3268-76. [Medline].
McDougle L, Klein GL, Hoehler FK. Management of hymenoptera sting anaphylaxis: a preventive medicine survey. J Emerg Med. Jan-Feb 1995;13(1):9-13. [Medline].
Patrick A, Roberts L, Poon-King P, Jeelal V. Acute renal failure due to multiple stings by Africanised bees. Report of the first case in Trinidad. West Indian Med J. Mar 1987;36(1):43-4. [Medline].
Pucci S, Antonicelli L, Bilo MB. Shortness of interval between two stings as risk factor for developing Hymenoptera venom allergy. Allergy. Dec 1994;49(10):894-6. [Medline].
Reisman RE. Unusual reactions to insect stings. Curr Opin Allergy Clin Immunol. Aug 2005;5(4):355-8. [Medline].
Roll A, Schmid-Grendelmeier P. Ultrarush immunotherapy in a patient with occupational allergy to bumblebee venom (Bombus terrestris). J Investig Allergol Clin Immunol. 2005;15(4):305-7. [Medline].
Schmidt JO. Let's not forget crawling Hymenoptera. Clin Exp Allergy. Jun 1994;24(6):511-4. [Medline].
Schumacher MJ, Tveten MS, Egen NB. Rate and quantity of delivery of venom from honeybee stings. J Allergy Clin Immunol. May 1994;93(5):831-5. [Medline].
Shimizu T, Hori T, Tokuyama K, et al. Clinical and immunologic surveys of Hymenoptera hypersensitivity in Japanese forestry workers. Ann Allergy Asthma Immunol. 1995;74(6):495-500. [Medline].
Stablein JJ, Lockey RF. Adverse reactions to ant stings. Clin Rev Allergy. May 1987;5(2):161-75. [Medline].
Stafford CT, Hutto LS, Rhoades RB, et al. Imported fire ant as a health hazard. South Med J. Dec 1989;82(12):1515-9. [Medline].
Valentine MD. Allergy to stinging insects. Ann Allergy. Jun 1993;70(6):427-32. [Medline].
Valkanas MA, Bowman S, Dailey MW. Electrocardiographic myocardial infarction without structural lesion in the setting of acute hymenoptera envenomation. Am J Emerg Med. Nov 2007;25(9):1082.e5-8. [Medline].
Vetter RS, Visscher PK, Camazine S. Mass envenomations by honey bees and wasps. West J Med. Apr 1999;170(4):223-7. [Medline].
Further Reading
Clinical guidelines
Stinging insect hypersensitivity: a practice parameter update. Moffitt JE, Golden DB, Reisman RE, Lee R, Nicklas R, Freeman T, deShazo R, Tracy J, Bernstein IL, Blessing-Moore J, Khan DA, Lang DM, Portnoy JM, Schuller DE, Spector SL, Tilles SA. Stinging insect hypersensitivity: a practice parameter update. J Allergy Clin Immunol 2004 Oct;114(4):869-86.
Keywords
bee stings, yellow jacket sting, hornet sting, ant stings, wasp stings, vespid stings, bee envenomations, Hymenoptera envenomations, ant envenomations, wasp envenomations, vespid envenomations, Apis species, wasps, ants, severe anaphylactoid reactions, angioedema, respiratoryarrest, fatal allergic reactions, urticaria, confluent red rash
syncope, anxiety, confusion, wheezing, tachypnea, hypotension, laryngoedema, lingular edema, uvular edema, delirium, shock, honeybee stings, Africanized honeybee, , isoamylacetate, pheromone, apiotherapy, fire ants, , fire ant venom, Harvester ants, species
Follow-up: Hymenoptera Stings