Hymenoptera Stings Treatment & Management
- Author: Carrie de Moor, MD; Chief Editor: Scott H Plantz, MD, FAAEM more...
Prehospital Care
Prehospital care must assess severity immediately and provide immediate appropriate treatment, because the most endangered patients die within 30 minutes of a sting.
Local reactions can be life threatening if swelling occludes the airway. Initiate invasive measures to secure the airway if this occurs. Otherwise, the following local care measures suffice.
- Provide supplemental oxygen
- Diphenhydramine limits the size of the local reaction.
- Clean the wound and remove the stinger if present.
- Apply ice or cool packs.
- Elevate the extremity to limit edema.
Manage generalized reactions similarly to anaphylaxis, even in the absence of shock. Increased vascular permeability in anaphylaxis may result in transfer of 50% of the intravascular fluid into the extravascular space within 10 minutes.[1] Check airway and ventilatory status. Treatment should include an initial intravenous (IV) bolus of 10-20 mL/kg isotonic crystalloids in addition to diphenhydramine and epinephrine.
If the patient has not removed the stinger, it should be removed as soon as possible by the first caregiver on the scene. Delay increases venom load, so the fastest removal technique is the best. Pinching and traction is an acceptable technique.
EMT or self-administration of intramuscular or subcutaneous epinephrine should be initiated immediately in the event of severe reaction. Intramuscular epinephrine injections into the lateral thigh provide more rapid absorption and higher plasma epinephrine levels than intramuscular or subcutaneous injections administered in the arm.[1]
Emergency Department Care
- Corticosteroids should be administered in severe cases to prevent recurrent or prolonged anaphylaxis, although acutely, they are not likely to improve symptoms.
- H2 blockers such as ranitidine and cimetidine may be given intravenously. Administration of one of these medications combined with diphenhydramine is superior to diphenhydramine alone.[1]
- In cases of refractory anaphylaxis, glucagon may be helpful if concomitant beta-blockers are preventing adequate response to epinephrine treatment.[1]
- Vasopressors such as dopamine can be used to provide vascular support.
- Patients developing respiratory arrest require ventilatory support.
- Blood products may be required in the event of disseminated intravascular coagulation (DIC).
- Repeated doses of epinephrine may be indicated for severe cases.
- In the event of cardiopulmonary arrest due to anaphylaxis, intravenous epinephrine should be administered as a first-line agent.[1]
Consultations
- Refer all patients with generalized reactions to an allergist as soon as possible, because risk of fatal reaction is inversely related to length of time since the last sting.
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