Decompression Sickness Differential Diagnoses

  • Author: Stephen A Pulley; Chief Editor: Joe Alcock, MD, MS   more...
 
Updated: Apr 16, 2012
 
 
 
Contributor Information and Disclosures
Author

Stephen A Pulley  MS, DO, FACOEP, Clinical Associate Professor, Department of Emergency Medicine, Philadelphia College of Osteopathic Medicine; Attending Faculty, Emergency Medicine Residency, Albert Einstein Healthcare Network; Attending Physician, Montgomery Hospital Medical Center

Stephen A Pulley is a member of the following medical societies: American College of Emergency Physicians, American College of Osteopathic Emergency Physicians, and American Osteopathic Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Eric M Kardon, MD, FACEP  Attending Emergency Physician, Georgia Emergency Medicine Specialists; Physician, Division of Emergency Medicine, Athens Regional Medical Center

Eric M Kardon, MD, FACEP is a member of the following medical societies: American College of Emergency Physicians

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

James Steven Walker, DO, MS  Clinical Professor of Surgery, Department of Surgery, University of Oklahoma College of Medicine

James Steven Walker, DO, MS is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, American College of Osteopathic Emergency Physicians, and American Osteopathic Association

Disclosure: Nothing to disclose.

John D Halamka, MD, MS  Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center

John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Chief Editor

Joe Alcock, MD, MS  Associate Professor, Department of Emergency Medicine, University of New Mexico Health Sciences Center; Chief, Emergency Medicine Service, New Mexico Veterans Affairs Health Care System

Joe Alcock, MD, MS is a member of the following medical societies: American Academy of Emergency Medicine

Disclosure: Nothing to disclose.

References
  1. Weaver LK. Monoplace hyperbaric chamber use of U.S. Navy Table 6: a 20-year experience. Undersea Hyperb Med. Mar-Apr 2006;33(2):85-8. [Medline].

  2. Auten JD, Kuhne MA, Walker HM 2nd, Porter HO. Neurologic decompression sickness following cabin pressure fluctuations at high altitude. Aviat Space Environ Med. Apr 2010;81(4):427-30. [Medline].

  3. Boussuges A, Succo E, Juhan-Vague I, Sainty JM. Activation of coagulation in decompression illness. Aviat Space Environ Med. Feb 1998;69(2):129-32. [Medline].

  4. Gempp E, Blatteau JE, Stephant E, Pontier JM, Constantin P, Pény C. MRI findings and clinical outcome in 45 divers with spinal cord decompression sickness. Aviat Space Environ Med. Dec 2008;79(12):1112-6. [Medline].

  5. Blatteau JE, Gempp E, Simon O, Coulange M, Delafosse B, Souday V, et al. Prognostic factors of spinal cord decompression sickness in recreational diving: retrospective and multicentric analysis of 279 cases. Neurocrit Care. Aug 2011;15(1):120-7. [Medline].

  6. James PB. Hyperbaric oxygenation in fluid microembolism. Neurol Res. Mar 2007;29(2):156-61. [Medline].

  7. Latham E, van Hoesen K, Grover I. Diplopia due to mask barotrauma. J Emerg Med. Nov 6 2008;[Medline].

  8. Uzun C, Yagiz R, Tas A, Adali MK, Inan N, Koten M, et al. Alternobaric vertigo in sport SCUBA divers and the risk factors. J Laryngol Otol. Nov 2003;117(11):854-60. [Medline].

  9. Klingmann C, Benton PJ, Ringleb PA, Knauth M. Embolic inner ear decompression illness: correlation with a right-to-left shunt. Laryngoscope. Aug 2003;113(8):1356-61. [Medline].

  10. Klingmann C, Praetorius M, Baumann I, Plinkert PK. Barotrauma and decompression illness of the inner ear: 46 cases during treatment and follow-up. Otol Neurotol. Jun 2007;28(4):447-54. [Medline].

  11. Goplen FK, Grønning M, Irgens A, Sundal E, Nordahl SH. Vestibular symptoms and otoneurological findings in retired offshore divers. Aviat Space Environ Med. Apr 2007;78(4):414-9. [Medline].

  12. Mitchell SJ, Doolette DJ. Selective vulnerability of the inner ear to decompression sickness in divers with right-to-left shunt: the role of tissue gas supersaturation. J Appl Physiol. Jan 2009;106(1):298-301. [Medline].

  13. Williams ST, Prior FG, Bryson P. Hematocrit change in tropical scuba divers. Wilderness Environ Med. 2007;18(1):48-53. [Medline].

  14. Newton HB, Burkart J, Pearl D, Padilla W. Neurological decompression illness and hematocrit: analysis of a consecutive series of 200 recreational scuba divers. Undersea Hyperb Med. Mar-Apr 2008;35(2):99-106. [Medline].

  15. Fahlman A, Dromsky DM. Dehydration effects on the risk of severe decompression sickness in a swine model. Aviat Space Environ Med. Feb 2006;77(2):102-6. [Medline].

  16. Gempp E, Blatteau JE, Pontier JM, Balestra C, Louge P. Preventive effect of pre-dive hydration on bubble formation in divers. Br J Sports Med. Mar 2009;43(3):224-8. [Medline].

  17. Hjelde A, Bergh K, Brubakk AO, Iversen OJ. Complement activation in divers after repeated air/heliox dives and its possible relevance to DCS. J Appl Physiol. Mar 1995;78(3):1140-4. [Medline].

  18. Huang KL, Lin YC. Activation of complement and neutrophils increases vascular permeability during air embolism. Aviat Space Environ Med. Apr 1997;68(4):300-5. [Medline].

  19. Shastri KA, Logue GL, Lundgren CE, Logue CJ, Suggs DF. Diving decompression fails to activate complement. Undersea Hyperb Med. Jun 1997;24(2):51-7. [Medline].

  20. Koch AE, Kirsch H, Reuter M, Warninghoff V, Rieckert H, Deuschl G. Prevalence of patent foramen ovale (PFO) and MRI-lesions in mild neurological decompression sickness (type B-DCS/AGE). Undersea Hyperb Med. May-Jun 2008;35(3):197-205. [Medline].

  21. Koch AE, Wegner-Bröse H, Warninghoff V, Deuschl G. Viewpoint: the type A- and the type B-variants of Decompression Sickness. Undersea Hyperb Med. Mar-Apr 2008;35(2):91-7. [Medline].

  22. Bove AA. Risk of decompression sickness with patent foramen ovale. Undersea Hyperb Med. 1998;25(3):175-8. [Medline].

  23. Germonpre P, Dendale P, Unger P, Balestra C. Patent foramen ovale and decompression sickness in sports divers. J Appl Physiol. May 1998;84(5):1622-6. [Medline].

  24. Aslam F, Shirani J, Haque AA. Patent foramen ovale: assessment, clinical significance and therapeutic options. South Med J. Dec 2006;99(12):1367-72. [Medline].

  25. Drighil A, El Mosalami H, Elbadaoui N, Chraibi S, Bennis A. Patent foramen ovale: a new disease?. Int J Cardiol. Oct 31 2007;122(1):1-9. [Medline].

  26. Harrah JD, O'Boyle PS, Piantadosi CA. Underutilization of echocardiography for patent foramen ovale in divers with serious decompression sickness. Undersea Hyperb Med. May-Jun 2008;35(3):207-11. [Medline].

  27. Cartoni D, De Castro S, Valente G, Costanzo C, Pelliccia A, Beni S, et al. Identification of professional scuba divers with patent foramen ovale at risk for decompression illness. Am J Cardiol. Jul 15 2004;94(2):270-3. [Medline].

  28. Trevett AJ, Sheehan C, Forbes R. Decompression illness presenting as breast pain. Undersea Hyperb Med. Mar-Apr 2006;33(2):77-9. [Medline].

  29. Honek T, Veselka J, Tomek A, Srámek M, Janugka J, Sefc L, et al. [Paradoxical embolization and patent foramen ovale in scuba divers: screening possibilities]. Vnitr Lek. Feb 2007;53(2):143-6. [Medline].

  30. Beda RD, Gill EA Jr. Patent foramen ovale: does it play a role in the pathophysiology of migraine headache?. Cardiol Clin. Feb 2005;23(1):91-6. [Medline].

  31. Wilmshurst PT, Nightingale S, Walsh KP, Morrison WL. Effect on migraine of closure of cardiac right-to-left shunts to prevent recurrence of decompression illness or stroke or for haemodynamic reasons. Lancet. Nov 11 2000;356(9242):1648-51. [Medline].

  32. Sastry S, MacNab A, Daly K, Ray S, McCollum C. Transcranial Doppler detection of venous-to-arterial circulation shunts: criteria for patent foramen ovale. J Clin Ultrasound. Jun 2009;37(5):276-80. [Medline].

  33. Leffler CT, White JC. Recompression treatments during the recovery of TWA Flight 800. Undersea Hyperb Med. Winter 1997;24(4):301-8. [Medline].

  34. Huang KL, Wu CP, Chen YL, Kang BH, Lin YC. Heat stress attenuates air bubble-induced acute lung injury: a novel mechanism of diving acclimatization. J Appl Physiol. Apr 2003;94(4):1485-90. [Medline].

  35. Su CL, Wu CP, Chen SY, Kang BH, Huang KL, Lin YC. Acclimatization to neurological decompression sickness in rabbits. Am J Physiol Regul Integr Comp Physiol. Nov 2004;287(5):R1214-8. [Medline].

  36. Sporting Goods Manufacturers Association. Sports Participation in America Topline Report 2004. Washington, DC, US: Sporting Goods Manufacturers Association; August 2004. [Full Text].

  37. Vermeulen EG, Stehouwer CD, Twisk JW, van den Berg M, de Jong SC, Mackaay AJ. Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial. Lancet. Feb 12 2000;355(9203):517-22. [Medline].

  38. Wang J, Corson K, Minky K, Mader J. Diver with acute abdominal pain, right leg paresthesias and weakness: a case report. Undersea Hyperb Med. 2002;29(4):242-6. [Medline].

  39. Sporting Goods Manufacturers Association. Sports Participation in America 2004. Washington, DC, US: Sporting Goods Manufacturers Association; August 2004. [Full Text].

  40. Sporting Goods Manufacturers Association. 2007 Sports and Fitness Participation Report. Washington, DC, US: Sporting Goods Manufacturers Association; 2007. [Full Text].

  41. van der Hulst GA, Buzzacott PL. Diver Health Survey score and probability of decompression sickness among occupational dive guides and instructors. Diving Hyperb Med. Mar 2012;42(1):18-23. [Medline].

  42. Gempp E, Blatteau JE. Preconditioning methods and mechanisms for preventing the risk of decompression sickness in scuba divers: a review. Res Sports Med. Jul 2010;18(3):205-18. [Medline].

  43. Bennett PB. What me bent?. In: Alert Diver (Divers Alert Network). Vol 2. 1997.

  44. Goldhahn RT Jr. Scuba diving deaths: a review and approach for the pathologist. Leg Med Annu. 1977;1976:109-32. [Medline].

  45. Lewis PR. Skin diving fatalities in New Zealand. N Z Med J. Jun 27 1979;89(638):472-5. [Medline].

  46. Arness MK. Scuba decompression illness and diving fatalities in an overseas military community. Aviat Space Environ Med. Apr 1997;68(4):325-33. [Medline].

  47. Klingmann C, Gonnermann A, Dreyhaupt J, Vent J, Praetorius M, Plinkert PK. Decompression illness reported in a survey of 429 recreational divers. Aviat Space Environ Med. Feb 2008;79(2):123-8. [Medline].

  48. Divers Alert Network. Report on Decompression Illness, DivingFatalities and Project Dive Exploration 2005 Edition. Durham, North Carolina, US: Divers Alert Network; 2005. [Full Text].

  49. Divers Alert Network. Annual Diving Report 2006 Edition. Durham, North Carolina, US: Divers Alert Network; Oct 11, 2006. [Full Text].

  50. Landsberg PG. South African underwater diving accidents, 1969-1976. S Afr Med J. Dec 25 1976;50(55):2155-59. [Medline].

  51. Denoble PJ, Caruso JL, Dear Gde L, Pieper CF, Vann RD. Common causes of open-circuit recreational diving fatalities. Undersea Hyperb Med. Nov-Dec 2008;35(6):393-406. [Medline].

  52. Tomassoni AJ. Cardiac problems associated with dysbarism. Cardiol Clin. May 1995;13(2):266-71. [Medline].

  53. Taylor DM, O'Toole KS, Ryan CM. Experienced, recreational scuba divers in Australia continue to dive despite medical contraindications. Wilderness Environ Med. 2002;13(3):187-93. [Medline].

  54. Buch DA, El Moalem H, Dovenbarger JA, Uguccioni DM, Moon RE. Cigarette smoking and decompression illness severity: a retrospective study in recreational divers. Aviat Space Environ Med. Dec 2003;74(12):1271-4. [Medline].

  55. Morgan WP, Raglin JS, O'Connor PJ. Trait anxiety predicts panic behavior in beginning scuba students. Int J Sports Med. May 2004;25(4):314-22. [Medline].

  56. Reuter M, Tetzlaff K, Hutzelmann A, Fritsch G, Steffens JC, Bettinghausen E, et al. MR imaging of the central nervous system in diving-related decompression illness. Acta Radiol. Nov 1997;38(6):940-4. [Medline].

  57. Sparacia G, Banco A, Sparacia B, Midiri M, Brancatelli G, Accardi M, et al. Magnetic resonance findings in scuba diving-related spinal cord decompression sickness. MAGMA. Jun 1997;5(2):111-5. [Medline].

  58. McCormac J, Mirvis SE, Cotta-Cumba C, Shanmuganathan K. Spinal myelopathy resulting from decompression sickness: MR findings in a case and review of the literature. Emerg Radiol. Oct 2002;9(4):240-2. [Medline].

  59. Blogg SL, Loveman GA, Seddon FM, Woodger N, Koch A, Reuter M, et al. Magnetic resonance imaging and neuropathology findings in the goat nervous system following hyperbaric exposures. Eur Neurol. 2004;52(1):18-28. [Medline].

  60. Gao GK, Wu D, Yang Y, Yu T, Xue J, Wang X, et al. Cerebral magnetic resonance imaging of compressed air divers in diving accidents. Undersea Hyperb Med. Jan-Feb 2009;36(1):33-41. [Medline].

  61. Aksoy FG. MR imaging of subclinical cerebral decompression sickness. A case report. Acta Radiol. Jan 2003;44(1):108-10. [Medline].

  62. Yoshiyama M, Asamoto S, Kobayashi N, Sugiyama H, Doi H, Sakagawa H, et al. Spinal cord decompression sickness associated with scuba diving: correlation of immediate and delayed magnetic resonance imaging findings with severity of neurologic impairment--a report on 3 cases. Surg Neurol. Mar 2007;67(3):283-7. [Medline].

  63. Tetzlaff K, Friege L, Hutzelmann A, Reuter M, Holl D, Leplow B. Magnetic resonance signal abnormalities and neuropsychological deficits in elderly compressed-air divers. Eur Neurol. 1999;42(4):194-9. [Medline].

  64. Blatteau JE, Jean F, Pontier JM, Blanche E, Bompar JM, Meaudre E. [Decompression sickness accident management in remote areas. Use of immediate in-water recompression therapy. Review and elaboration of a new protocol targeted for a mission at Clipperton atoll]. Ann Fr Anesth Reanim. Aug 2006;25(8):874-83. [Medline].

  65. Gold D, Aiyarak S, Wongcharoenyong S, Geater A, Juengprasert W, Gerth WA. The indigenous fisherman divers of Thailand: diving practices. Int J Occup Saf Ergon. 2000;6(1):89-112. [Medline].

  66. Gold D, Geater A, Aiyarak S, Juengprasert W, Chuchaisangrat B, Samakkaran A. The indigenous fisherman divers of Thailand: in-water recompression. Int Marit Health. 1999;50(1-4):39-48. [Medline].

  67. Gold D, Geater A, Aiyarak S, Wongcharoenyong S, Juengprasert W, Johnson M, et al. The indigenous fisherman divers of Thailand: diving-related mortality and morbidity. Int J Occup Saf Ergon. 2000;6(2):147-67. [Medline].

  68. Longphre JM, Denoble PJ, Moon RE, Vann RD, Freiberger JJ. First aid normobaric oxygen for the treatment of recreational diving injuries. Undersea Hyperb Med. Jan-Feb 2007;34(1):43-9. [Medline].

  69. Bessereau J, Coulange M, Genotelle N, Barthélémy A, Michelet P, Bruguerolle B, et al. [Aspirin in decompression sickness]. Therapie. Nov-Dec 2008;63(6):419-23. [Medline].

  70. de Watteville G. [A critical assessment of Trendelenburg's position in the acute phase after a diving accident]. Schweiz Z Sportmed. Sep 1993;41(3):123-5. [Medline].

  71. Goldenberg I, Shupak A, Shoshani O. Oxy-helium treatment for refractory neurological decompression sickness: a case report. Aviat Space Environ Med. Jan 1996;67(1):57-60. [Medline].

  72. Shupak A, Melamed Y, Ramon Y, Bentur Y, Abramovich A, Kol S. Helium and oxygen treatment of severe air-diving-induced neurologic decompression sickness. Arch Neurol. Mar 1997;54(3):305-11. [Medline].

  73. Tempel R, Severance HW. Proposing short-term observation units for the management of decompression illness. Undersea Hyperb Med. Mar-Apr 2006;33(2):89-94. [Medline].

  74. Kot J, Sicko Z, Michalkiewicz M, Lizak E, Góralczyk P. Recompression treatment for decompression illness: 5-year report (2003-2007) from National Centre for Hyperbaric Medicine in Poland. Int Marit Health. 2008;59(1-4):69-80. [Medline].

  75. Gil A, Shupak A, Lavon H, Adir Y. [Decompression sickness in divers treated at the Israel Naval Medical Institute between the years 1992 to 1997]. Harefuah. May 1 2000;138(9):751-4, 806. [Medline].

  76. Cianci P, Slade JB Jr. Delayed treatment of decompression sickness with short, no-air-break tables: review of 140 cases. Aviat Space Environ Med. Oct 2006;77(10):1003-8. [Medline].

  77. Weisher DD. Resolution of neurological DCI after long treatment delays. Undersea Hyperb Med. May-Jun 2008;35(3):159-61. [Medline].

  78. Dunford RG, Vann RD, Gerth WA, Pieper CF, Huggins K, Wacholtz C, et al. The incidence of venous gas emboli in recreational diving. Undersea Hyperb Med. 2002;29(4):247-59. [Medline].

  79. Barratt DM, Van Meter K. Decompression sickness in Miskito Indian lobster divers: review of 229 cases. Aviat Space Environ Med. Apr 2004;75(4):350-3. [Medline].

  80. MacDonald RD, O'Donnell C, Allan GM, Breeck K, Chow Y, DeMajo W. Interfacility transport of patients with decompression illness: literature review and consensus statement. Prehosp Emerg Care. Oct-Dec 2006;10(4):482-7. [Medline].

  81. Bennett PB. Putting on the brakes: extra safety stops and slower ascent rates may help reduce decompression injuries. In: Alert Diver (Divers Alert Network). 2001:1.

  82. Bennett PB, Marroni A, Cronje FJ, Cali-Corleo R, Germonpre P, Pieri M, et al. Effect of varying deep stop times and shallow stop times on precordial bubbles after dives to 25 msw (82 fsw). Undersea Hyperb Med. Nov-Dec 2007;34(6):399-406. [Medline].

  83. Jankowski LW, Tikuisis P, Nishi RY. Exercise effects during diving and decompression on postdive venous gas emboli. Aviat Space Environ Med. Jun 2004;75(6):489-95. [Medline].

  84. Dujic Z, Valic Z, Brubakk AO. Beneficial role of exercise on scuba diving. Exerc Sport Sci Rev. Jan 2008;36(1):38-42. [Medline].

  85. Dujic Z, Palada I, Obad A, Duplancic D, Bakovic D, Valic Z. Exercise during a 3-min decompression stop reduces postdive venous gas bubbles. Med Sci Sports Exerc. Aug 2005;37(8):1319-23. [Medline].

  86. O'Connor PE. The nontechnical causes of diving accidents: can U.S. Navy divers learn from other industries?. Undersea Hyperb Med. Jan-Feb 2007;34(1):51-9. [Medline].

  87. Blatteau JE, Souraud JB, Gempp E, Boussuges A. Gas nuclei, their origin, and their role in bubble formation. Aviat Space Environ Med. Oct 2006;77(10):1068-76. [Medline].

  88. Philp RB, Freeman D, Francey I, Bishop B. Hematology and blood chemistry in saturation diving: I. Antiplatelet drugs, aspirin, and VK744. Undersea Biomed Res. Dec 1975;2(4):233-49. [Medline].

  89. Pontier JM, Blatteau JE, Vallée N. Blood platelet count and severity of decompression sickness in rats after a provocative dive. Aviat Space Environ Med. Aug 2008;79(8):761-4. [Medline].

  90. Pontier JM, Jimenez C, Blatteau JE. Blood platelet count and bubble formation after a dive to 30 msw for 30 min. Aviat Space Environ Med. Dec 2008;79(12):1096-9. [Medline].

  91. Gutvik CR, Brubakk AO. A dynamic two-phase model for vascular bubble formation during decompression of divers. IEEE Trans Biomed Eng. Mar 2009;56(3):884-9. [Medline].

  92. Mollerlokken A, Berge VJ, Jorgensen A, Wisloff U, Brubakk AO. Effect of a short-acting NO donor on bubble formation from a saturation dive in pigs. J Appl Physiol. Dec 2006;101(6):1541-5. [Medline].

  93. Dujic Z, Palada I, Valic Z, Duplancic D, Obad A, Wisløff U. Exogenous nitric oxide and bubble formation in divers. Med Sci Sports Exerc. Aug 2006;38(8):1432-5. [Medline].

  94. Madden LA, Laden G. Gas bubbles may not be the underlying cause of decompression illness - The at-depth endothelial dysfunction hypothesis. Med Hypotheses. Apr 2009;72(4):389-92. [Medline].

  95. Dujic Z, Obad A, Palada I, Ivancev V, Valic Z. Venous bubble count declines during strenuous exercise after an open sea dive to 30 m. Aviat Space Environ Med. Jun 2006;77(6):592-6. [Medline].

  96. Wisløff U, Brubakk AO. Aerobic endurance training reduces bubble formation and increases survival inrats exposed to hyperbaric pressure. J Physiol. Dec 1 2001;537(Pt 2):607-11. [Medline].

  97. Dujic Z, Duplancic D, Marinovic-Terzic I, Bakovic D, Ivancev V, Valic Z, et al. Aerobic exercise before diving reduces venous gas bubble formation in humans. J Physiol. Mar 16 2004;555(Pt 3):637-42. [Medline].

  98. Loset A Jr, Mollerlokken A, Berge V, Wisloff U, Brubakk AO. Post-dive bubble formation in rats: effects of exercise 24 h ahead repeated 30min before the dive. Aviat Space Environ Med. Sep 2006;77(9):905-8. [Medline].

  99. Berge VJ, Jørgensen A, Løset A, Wisløff U, Brubakk AO. Exercise ending 30 min pre-dive has no effect on bubble formation in the rat. Aviat Space Environ Med. Apr 2005;76(4):326-8. [Medline].

  100. Blatteau JE, Boussuges A, Gempp E, Pontier JM, Castagna O, Robinet C, et al. Haemodynamic changes induced by submaximal exercise before a dive and its consequences on bubble formation. Br J Sports Med. Jun 2007;41(6):375-9. [Medline].

  101. Wisløff U, Richardson RS, Brubakk AO. Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness?. J Physiol. Mar 16 2004;555:825-9. [Medline].

  102. Wisløff U, Richardson RS, Brubakk AO. NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats. J Physiol. Jan 15 2003;546:577-82. [Medline].

  103. Pontier JM, Guerrero F, Castagna O. Bubble formation and endothelial function before and after 3 months of dive training. Aviat Space Environ Med. Jan 2009;80(1):15-9. [Medline].

  104. Castagna O, Gempp E, Blatteau JE. Pre-dive normobaric oxygen reduces bubble formation in scuba divers. Eur J Appl Physiol. May 2009;106(2):167-72. [Medline].

  105. Mahon RT, Dainer HM, Gibellato MG, Soutiere SE. Short oxygen prebreathe periods reduce or prevent severe decompression sickness in a 70-kg swine saturation model. J Appl Physiol. Apr 2009;106(4):1459-63. [Medline].

  106. Sobakin AS, Wilson MA, Lehner CE, Dueland RT, Gendron-Fitzpatrick AP. Oxygen pre-breathing decreases dysbaric diseases in UW sheep undergoing hyperbaric exposure. Undersea Hyperb Med. Jan-Feb 2008;35(1):61-7. [Medline].

  107. Blatteau JE, Gempp E, Balestra C, Mets T, Germonpre P. Predive sauna and venous gas bubbles upon decompression from 400 kPa. Aviat Space Environ Med. Dec 2008;79(12):1100-5. [Medline].

  108. Candito M, Candito E, Chatel M, van Obberghen E, Dunac A. [Homocysteinemia and thrombophilic factors in unexplained decompression sickness]. Rev Neurol (Paris). Sep 2006;162(8-9):840-4. [Medline].

  109. Candito M, Chatel M, Candito E, Lapoussiere M, Mengual R, Van Obberghen E, et al. [Thrombophilic factors in divers with undeserved decompression sickness]. Pathol Biol (Paris). Apr 2006;54(3):155-8. [Medline].

  110. Eftedal OS, Lydersen S, Brubakk AO. The relationship between venous gas bubbles and adverse effects of decompression after air dives. Undersea Hyperb Med. Mar-Apr 2007;34(2):99-105. [Medline].

  111. Tufan K, Ademoglu A, Kurtaran E, Yildiz G, Aydin S, Egi SM. Automatic detection of bubbles in the subclavian vein using Doppler ultrasound signals. Aviat Space Environ Med. Sep 2006;77(9):957-62. [Medline].

  112. Ball R, Schwartz SL. Kinetic and dynamic models of diving gases in decompression sickness prevention. Clin Pharmacokinet. 2002;41(6):389-402. [Medline].

  113. Brubakk AO, Arntzen AJ, Wienke BR, Koteng S. Decompression profile and bubble formation after dives with surface decompression: experimental support for a dual phase model of decompression. Undersea Hyperb Med. 2003;30(3):181-93. [Medline].

  114. Montcalm-Smith E, Caviness J, Chen Y, McCarron RM. Stress biomarkers in a rat model of decompression sickness. Aviat Space Environ Med. Feb 2007;78(2):87-93. [Medline].

  115. Dromsky DM, Spiess BD, Fahlman A. Treatment of decompression sickness in swine with intravenous perfluorocarbon emulsion. Aviat Space Environ Med. Apr 2004;75(4):301-5. [Medline].

  116. Zhu J, Hullett JB, Somera L, Barbee RW, Ward KR, Berger BE, et al. Intravenous perfluorocarbon emulsion increases nitrogen washout after venous gas emboli in rabbits. Undersea Hyperb Med. Jan-Feb 2007;34(1):7-20. [Medline].

  117. Spiess BD. Perfluorocarbon emulsions as a promising technology: a review of tissue and vascular gas dynamics. J Appl Physiol. Apr 2009;106(4):1444-52. [Medline].

  118. Spiess BD, Zhu J, Pierce B, Weis R, Berger BE, Reses J, et al. Effects of perfluorocarbon infusion in an anesthetized swine decompression model. J Surg Res. May 1 2009;153(1):83-94. [Medline].

  119. Dainer H, Nelson J, Brass K, Montcalm-Smith E, Mahon R. Short oxygen prebreathing and intravenous perfluorocarbon emulsion reduces morbidity and mortality in a swine saturation model of decompression sickness. J Appl Physiol. Mar 2007;102(3):1099-104. [Medline].

  120. Camporesi EM. Diving and pregnancy. Semin Perinatol. Aug 1996;20(4):292-302. [Medline].

  121. Lemaitre F, Carturan D, Tourney-Chollet C, Gardette B. Circulating venous bubbles in children after diving. Pediatr Exerc Sci. Feb 2009;21(1):77-85. [Medline].

  122. AIDA International. AIDA International World Records. International Association for Development of Apnea. Available at http://www.hotweb.se/aspportal1/code/page.asp?sType=wr&CountryID=4&actID=3&ObjectID=136. Accessed October 5, 2007.

  123. Arieli R, Svidovsky P, Abramovich A. Decompression sickness in the rat following a dive on trimix: recompression therapy with oxygen vs. heliox and oxygen. J Appl Physiol. Apr 2007;102(4):1324-8. [Medline].

  124. Bennett PB, Elliott DH. The Physiology and Medicine of Diving and Compressed Air Work. 2nd ed. Baltimore: Lippincott William & Wilkins; 1975.

  125. Butler BD, Little T, Cogan V, Powell M. Hyperbaric oxygen pre-breathe modifies the outcome of decompression sickness. Undersea Hyperb Med. Nov-Dec 2006;33(6):407-17. [Medline].

  126. Carturan D, Boussuges A, Burnet H, Fondarai J, Vanuxem P, Gardette B. Circulating venous bubbles in recreational diving: relationships with age, weight, maximal oxygen uptake and body fat percentage. Int J Sports Med. Aug 1999;20(6):410-4. [Medline].

  127. Cogar WB. Intravenous lidocaine as adjunctive therapy in the treatment of decompression illness. Ann Emerg Med. Feb 1997;29(2):284-6. [Medline].

  128. Davis JC, Kizer KW. Diving medicine. In: Auerbach PS, Geehr EC, eds. Management of Wilderness and Environmental Emergencies. 2nd ed. St. Louis: CV Mosby; 1989:879-905.

  129. Dickey LS. Barotrauma. In: Tintinalli JE, Krome RL, eds. Emergency Medicine: A Comprehensive Study Guide. NY: McGraw-Hill Co; 985-993.

  130. Dujic Z, Palada I, Obad A, Duplancic D, Brubakk AO, Valic Z. Exercise-induced intrapulmonary shunting of venous gas emboli does not occur after open-sea diving. J Appl Physiol. Sep 2005;99(3):944-9. [Medline].

  131. Duplessis C, Hoffer M. Tinnitus in an active duty navy diver: A review of inner ear barotrauma, tinnitus, and its treatment. Undersea Hyperb Med. Jul-Aug 2006;33(4):223-30. [Medline].

  132. Gempp E, Blatteau JE. Neurological disorders after repetitive breath-hold diving. Aviat Space Environ Med. Sep 2006;77(9):971-3. [Medline].

  133. Gorman D, Sames C, Drewry A, Bodicoat S. A case of type 3 DCS with a radiologically normal spinal cord. Intern Med J. Mar 2006;36(3):193-6. [Medline].

  134. Hardy KR. Diving-related emergencies. Emerg Med Clin North Am. Feb 1997;15(1):223-40. [Medline].

  135. Hart AJ, White SA, Conboy PJ, Bodiwala G, Quinton D. Open water scuba diving accidents at Leicester: five years' experience. J Accid Emerg Med. May 1999;16(3):198-200. [Medline].

  136. Hutter CD. Dysbaric osteonecrosis: a reassessment and hypothesis. Med Hypotheses. Apr 2000;54(4):585-90. [Medline].

  137. Hyldegaard O, Jensen T. Effect of heliox, oxygen and air breathing on helium bubbles after heliox diving. Undersea Hyperb Med. Mar-Apr 2007;34(2):107-22. [Medline].

  138. Hyldegaard O, Jensen T. Effect of heliox, oxygen and air breathing on helium bubbles after heliox diving. Undersea Hyperb Med. Mar-Apr 2007;34(2):107-22. [Medline].

  139. Jerrard DA. Diving medicine. Emerg Med Clin North Am. May 1992;10(2):329-38. [Medline].

  140. Kizer KW. Dysbarism. In: Rosen R, Barken RM, Brean CR, et al, eds. In: Emergency Medicine: Concepts and Clinical Practice. CV Mosby Co: 1992:881-888.

  141. Lafay V. [The heart and underwater diving]. Arch Mal Coeur Vaiss. Nov 2006;99(11):1115-9. [Medline].

  142. Lindholm P, Lundgren CE. The physiology and pathophysiology of human breath-hold diving. J Appl Physiol. Jan 2009;106(1):284-92. [Medline].

  143. Manabe Y, Sakai K, Kashihara K, Shohmori T. Presumed venous infarction in spinal decompression sickness. AJNR Am J Neuroradiol. Sep 1998;19(8):1578-80. [Medline].

  144. Marabotti C, Chiesa F, Scalzini A, Antonelli F, Lari R, Franchini C, et al. Cardiac and humoral changes induced by recreational scuba diving. Undersea Hyperb Med. 1999;26(3):151-8. [Medline].

  145. Masuda Y, Tanabe T, Murata Y, Kitahara S. Protective effect of edaravone in inner-ear barotrauma in guinea pigs. J Laryngol Otol. Jul 2006;120(7):524-7. [Medline].

  146. Miller JW, Bachrach AJ, Walsh JM. Assessment of vertical excursions and open-sea psychological performance at depths to 250 fsw. Undersea Biomed Res. Dec 1976;3(4):339-49. [Medline].

  147. Mitchell SJ, Cronjé FJ, Meintjes WA, Britz HC. Fatal respiratory failure during a "technical" rebreather dive at extreme pressure. Aviat Space Environ Med. Feb 2007;78(2):81-6. [Medline].

  148. National Oceanic and Atmospheric Administration. Diving for science and technology. In: NOAA Diving Manual. Washington, DC; 1990.

  149. Obad A, Palada I, Valic Z, Ivancev V, Bakovic D, Wisloff U, et al. The effects of acute oral antioxidants on diving-induced alterations in human cardiovascular function. J Physiol. Feb 1 2007;578(Pt 3):859-70. [Medline].

  150. Ramos CC, Rapoport PB, Brito Neto RV. Clinical and tympanometric findings in repeated recreational scuba diving. Travel Med Infect Dis. Feb 2005;3(1):19-25. [Medline].

  151. Sade K, Wiesel O, Kivity S, Levo Y. [Asthma and scuba diving: can asthmatic patients dive?]. Harefuah. Apr 2007;146(4):286-90, 317. [Medline].

  152. Schipke JD, Gams E, Kallweit O. Decompression sickness following breath-hold diving. Res Sports Med. Jul-Sep 2006;14(3):163-78. [Medline].

  153. Shupak A, Gil A, Nachum Z, Miller S, Gordon CR, Tal D. Inner ear decompression sickness and inner ear barotrauma in recreational divers: a long-term follow-up. Laryngoscope. Dec 2003;113(12):2141-7. [Medline].

  154. Spira A. Diving and marine medicine review part II: diving diseases. J Travel Med. Sep 1999;6(3):180-98. [Medline].

  155. Taylor DM, Lippmann J, Smith D. The absence of hearing loss in otologically asymptomatic recreational scuba divers. Undersea Hyperb Med. Mar-Apr 2006;33(2):135-41. [Medline].

  156. Togawa S, Maruyama M, Yamami N, Nakayama H, Shibayama M, Kawashima M, et al. Dissociation of neurological deficits in spinal decompression illness. Undersea Hyperb Med. Jul-Aug 2006;33(4):265-70. [Medline].

  157. Undersea Medical Society. Program and abstracts: Undersea Medical Society annual scientific meeting. 11-14 June 1985, Long Beach, California. Undersea Biomed Res. Mar 1985;12(1 Suppl):1-65. [Medline].

  158. Uzun C, Yagiz R, Tas A, Adali MK, Inan N, Koten M, et al. Alternobaric vertigo in sport SCUBA divers and the risk factors. J Laryngol Otol. Nov 2003;117(11):854-60. [Medline].

  159. Van Rees Vellinga TP, Verhoeven AC, Van Dijk FJ, Sterk W. Health and efficiency in trimix versus air breathing in compressed air workers. Undersea Hyperb Med. Nov-Dec 2006;33(6):419-27. [Medline].

  160. Vermeulen EG, Stehouwer CD, Valk J, van der Knaap M, van den Berg M, Twisk JW, et al. Effect of homocysteine-lowering treatment with folic acid plus vitamin B oncerebrovascular atherosclerosis and white matter abnormalities as determined byMRA and MRI: a placebo-controlled, randomized trial. Eur J Clin Invest. Apr 2004;34(4):256-61. [Medline].

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Illustration of Dalton gas law. As an individual descends, the total pressure of breathing air increases and the partial pressures of the individual components have to increase proportionally. Nitrogen at higher partial pressures alters the electrical properties of cerebral cellular membranes, causing an anesthetic effect. Oxygen at higher partial pressures can cause CNS oxygen toxicity.
Illustration of Henry gas law. If nitrogen is added to a bottle, it diffuses into and equilibrates with the fluid. If pressure is suddenly released (decreased), such as when an individual ascends rapidly, a lag occurs before nitrogen can diffuse back to the nonfluid space. This delay causes nitrogen to bubble while still in the fluid.
 
 
 
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