Constipation in Emergency Medicine Follow-up
- Author: Dave A Holson, MD, MBBS, MPH; Chief Editor: Barry E Brenner, MD, PhD, FACEP more...
Further Inpatient Care
- Patients with the following warrant admission and surgical evaluation:
- Obstructive symptoms
- Nonrectal impactions
- Fever and dehydration
- Diabetes mellitus is an immunosuppressive illness and judicious evaluation of this patient population is warranted.
Further Outpatient Care
- Further outpatient care should include contact with the primary care provider to ensure follow-up.
- Referral to a gastroenterologist is warranted for patients with the following:
- Constipation of recent onset
- Rectal bleeding or heme-positive stool
- Chronic constipation associated with weight loss, anemia, or change in stool consistency
- Refractory constipation
- Rectal prolapse
- Constipation requiring chronic laxative use
- Future directions
- Prokinetic agents that stimulate serotonergic enteric nervous system receptors
- Although significant promise had been shown with this new class of drugs, 2 agents, cisapride and tegaserod have been withdrawn from the US market in 2000 and 2008, respectively.
- The mixed 5-HT4 receptor agonist/5-HT3 receptor antagonist renzapride has been tested to assess its efficacy and safety in the treatment of chronic constipation.[15]
- Linaclotide, an agonist of guanylate cyclase type-c, has just completed phase 3 clinical trials and has been shown to increase SBMs and CSBMs.[13]
- Enteric nervous system neurotrophin - Neurotrophin-3 stimulates the development, growth, and function of the nervous system.
- Electrical stimulation of the colon
- Stem cells to repopulate dysfunctional neurons
- Prokinetic agents that stimulate serotonergic enteric nervous system receptors
Inpatient & Outpatient Medications
- Bulk-forming agent: Psyllium (eg, Metamucil) increases frequency and softens stool consistency.
- Emollient: Docusate sodium (eg, Colace) improves hard bowel movements.
- Lukewarm tap water enema: This treatment facilitates rapid relief of symptoms and may help regulate further bowel movements.
Deterrence/Prevention
Deterrence and prevention of constipation may include the following:
- Adequate fluid intake (ie, eight 8-oz glasses of water per day)
- Regular exercise
- High-fiber diet
- Avoidance or decreased use of constipating medications
- Regular bowel habits with attempted bowel movements at the same time daily may help symptoms, especially after meals when the gastrocolic reflex is strongest.
Complications
Complications of constipation may include the following:
- Fecal impaction
- Bowel obstruction
- Stercoral ulceration/perforation
- Megacolon
- Volvulus
- Rectal prolapse
- Urinary retention
Prognosis
- Most active patients do well with medical management.
- Constipation is an ongoing problem for patients who are bedridden or otherwise debilitated.
- Colectomy usually is reserved for patients with slow transit constipation who fail to respond to 6 months of medical management with good patient compliance.
Patient Education
- Listening to patients' concepts of normal bowel activity is important.
- Instituting a behavior modification program allows patients to become more aware of and responsive to normal urges to defecate.
- Emphasize the importance of a high-fiber diet.
- Emphasize adequate fluid intake.
- Emphasize regular exercise.
- For excellent patient education resources, visit eMedicine's Esophagus, Stomach, and Intestine Center. Also, see eMedicine's patient education articles Constipation in Adults and Constipation in Children.
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