Anal Fistulas and Fissures Clinical Presentation
- Author: Ingrid Legall, MD; Chief Editor: Robert E O'Connor, MD, MPH more...
History
Rectal pain is usually described as burning, cutting, or tearing and occurs with bowel movements. Spasm of the anus is very suspicious for an anal fissure.
Typically, bright-red blood appears on the surface of stools, but blood usually is not mixed into stool. Occasionally, blood is found on toilet paper after wiping. The patient may sometimes report no bleeding.
A patient with an anal fistula may complain of recurrent malodorous perianal drainage, pruritus, recurrent abscesses, fever, or perianal pain due to an occluded tract. Pain occurs with sitting, moving, defecating, and even coughing. It usually is throbbing in quality and is constant throughout the day. Pain occasionally resolves spontaneously with reopening of a tract or formation of a new outflow tract.
Physical Examination
The physical examination of patients with fistulas or fissures begins by optimizing patient placement; place the patient in the left lateral decubitus position with knees drawn up toward the chest.[4] Examine the patient carefully to help avoid inflicting further pain or sphincter spasm. Examination may be facilitated by application of a topical anesthetic, such as lidocaine jelly, before digital rectal examination.
Rectal examination is generally difficult to tolerate because of sphincter spasm and pain. Acute fissures are erythematous and bleed easily.
Most fissures are visible externally when the patient bears down as if having a bowel movement. Note the depth of the fissure and its orientation to the midline, often described using clock orientation of the hour hand. Most tears are found in the posterior midline.
With chronic fissures, the classic fissure triad may be seen, as follows:
- Deep ulcer
- Sentinel pile, which forms when the base of the fissure becomes edematous and hypertrophic (a resolving sentinel pile can result in a permanent skin tag or may become associated with a fistulous tract)
- Enlarged anal papillae
Bidigital rectal examination in a patient with a fistula-in-ano may reveal an indurated tract or cord. A fistula can be identified by small circles of granulation tissue, which exude pus when compressed if tissue is patent. A fistulous tract that opens internally can be visualized with the aid of an anoscope. Inguinal lymph nodes may be enlarged and painful.
In an acute fistulous abscess, cardinal signs of inflammation, rubor, dolor, calor, and tumor (eg, erythema, pain, increased temperature, edema) may be found. Examination of the anus reveals a linear tear in fissure-in-ano.
Complications
Constipation or fecal impaction may occur. The pain from an anal fissure can be so overwhelming that it discourages people from defecating. Acute fissures can become chronic, and sentinel pile can result. A permanent skin tag can result, and fistulas may form.
The following complications may occur with surgical intervention[1, 5] :
- Urinary retention
- Bleeding
- Abscess formation
- Flatus and liquid incontinence
- Recurrence of fissures
Without treatment, chronically infected fistulas may cause systemic illness. Carcinoma has been reported in cases of chronic untreated anorectal fistulas.
Garcia-Aguilar J, Belmonte C, Wong WD, Goldberg SM, Madoff RD. Anal fistula surgery. Factors associated with recurrence and incontinence. Dis Colon Rectum. Jul 1996;39(7):723-9. [Medline].
North JH Jr, Weber TK, Rodriguez-Bigas MA, Meropol NJ, Petrelli NJ. The management of infectious and noninfectious anorectal complications in patients with leukemia. J Am Coll Surg. Oct 1996;183(4):322-8. [Medline].
Nordgren S, Fasth S, Hulten L. Anal fistulas in Crohn's disease: incidence and outcome of surgical treatment. Int J Colorectal Dis. Dec 1992;7(4):214-8. [Medline].
Kuehn HG, Gebbensleben O, Hilger Y, Rohde H. Relationship between anal symptoms and anal findings. Int J Med Sci. 2009;6(2):77-84. [Medline].
Oh C, Divino CM, Steinhagen RM. Anal fissure. 20-year experience. Dis Colon Rectum. Apr 1995;38(4):378-82. [Medline].
Nelson RL, Thomas K, Morgan J, Jones A. Non surgical therapy for anal fissure. Cochrane Database Syst Rev. Feb 15 2012;2:CD003431. [Medline].
Corno F, Marano A, Volpatto S, Mistrangelo P. [Topical use of glyceryl-trinitrate in the treatment of anal fissure]. Minerva Chir. Jun 2009;64(3):307-11. [Medline].
Vila S, Garcia C, Piscoya A, De Los Rios R, L Pinto J, Huerta Mercado J, et al. [Use of glycerol trinitrate in an ointment for the management of chronic anal fissure at the National Hospital "Cayetano Heredia"]. Rev Gastroenterol Peru. Jan-Mar 2009;29(1):33-9. [Medline].
Nitroglycerin rectal ointment (Rectiv) [package insert]. ProStrakan, Inc; 2011. [Full Text].
Khan JS, Tan N, Nikkhah D, Miles AJ. Subcutaneous lateral internal sphincterotomy (SLIS)-a safe technique for treatment of chronic anal fissure. Int J Colorectal Dis. Jul 21 2009;[Medline].
Mousavi SR, Sharifi M, Mehdikhah Z. A comparison between the results of fissurectomy and lateral internal sphincterotomy in the surgical management of chronic anal fissure. J Gastrointest Surg. Jul 2009;13(7):1279-82. [Medline].
Brisinda G, Cadeddu F, Mazzeo P, Maria G. Botulinum toxin A for the treatment of chronic anal fissure. Expert Rev Gastroenterol Hepatol. Dec 2007;1(2):219-28. [Medline].
Chung CC, Choi CL, Kwok SP, Leung KL, Lau WY, Li AK. Anal and perianal tuberculosis: a report of three cases in 10 years. J R Coll Surg Edinb. Jun 1997;42(3):189-90. [Medline].
Farquharson M. Haemorrhoids, fissures and anal fistulae. Trop Doct. Oct 2002;32(4):196-201. [Medline].
Isbister WH, Prasad J. Fissure in ano. Aust N Z J Surg. Feb 1995;65(2):107-8. [Medline].
Jonas and Scholefield. American Gastroenterology Association. 2004.

