Abdominal Pain in Elderly Persons Medication
- Author: E David Bryan, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP more...
Medication Summary
The goals of pharmacotherapy are to reduce morbidity and prevent complications.
Antispasmodics
Class Summary
Believed to work centrally by suppressing conduction in the vestibular cerebellar pathways. They may have an inhibitory effect on the parasympathetic nervous system.
Dicyclomine (Bentyl)
Smooth muscle relaxant. Fairly effective in relieving pain from biliary tract disease. May be administered PO/IM. Cannot be administered IV.
Glycopyrrolate (Robinul)
Acts in smooth muscle, the CNS, and secretory glands where it blocks action of acetylcholine at parasympathetic sites. Similar to dicyclomine in effects. May be administered IV.
Opioid Analgesics
Class Summary
Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma or have sustained injuries.
Morphine sulfate (Duramorph, Astramorph, MS Contin)
Generally safe in low-to-moderate doses in abdominal pain. Not recommended for biliary tract disease because of potential for sphincter of Oddi spasm.
Meperidine (Demerol)
Generally safe in low-to-moderate doses in abdominal pain. Causes less sphincter of Oddi spasm than morphine but has potential to cause CNS adverse effects.
Fentanyl citrate (Sublimaze)
Potent narcotic analgesic with much shorter half-life than morphine sulfate. Potential advantages in management of abdominal pain include short duration of action and lack of histamine release. Potential disadvantage is potential for sphincter of Oddi spasm.
Esses D, Birnbaum A, Bijur P, et al. Ability of CT to alter decision making in elderly patients with acute abdominal pain. Am J Emerg Med. Jul 2004;22(4):270-2. [Medline].
Hustey FM, Meldon SW, Banet GA, et al. The use of abdominal computed tomography in older ED patients with acute abdominal pain. Am J Emerg Med. May 2005;23(3):259-65. [Medline].
Lewis LM, Banet GA, Blanda M, et al. Etiology and clinical course of abdominal pain in senior patients: a prospective, multicenter study. J Gerontol A Biol Sci Med Sci. Aug 2005;60(8):1071-6. [Medline].
Laurell H, Hansson LE, Gunnarsson U. Acute abdominal pain among elderly patients. Gerontology. 2006;52(6):339-44. [Medline].
Lee JF, Leow CK, Lau WY. Appendicitis in the elderly. Aust N Z J Surg. Aug 2000;70(8):593-6. [Medline].
Samaras N, Chevalley T, Samaras D, Gold G. Older patients in the emergency department: a review. Ann Emerg Med. Sep 2010;56(3):261-9. [Medline].
Surov A, Mannes F, Behrmann C. Vomiting and painful abdomen in dementia. Gastroenterology. Sep 2010;139(3):e10-1. [Medline].
Fleischmann D. MDCT of renal and mesenteric vessels. Eur Radiol. Dec 2003;13 Suppl 5:M94-101. [Medline].
Cademartiri F, Raaijmakers RH, Kuiper JW, et al. Multi-detector row CT angiography in patients with abdominal angina. Radiographics. Jul-Aug 2004;24(4):969-84. [Medline].
Kirkpatrick ID, Kroeker MA, Greenberg HM. Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia: initial experience. Radiology. Oct 2003;229(1):91-8. [Medline].
Attard AR, Corlett MJ, Kidner NJ, et al. Safety of early pain relief for acute abdominal pain. BMJ. Sep 5 1992;305(6853):554-6. [Medline].
Bugliosi TF, Meloy TD, Vukov LF. Acute abdominal pain in the elderly. Ann Emerg Med. Dec 1990;19(12):1383-6. [Medline].
Cassel CK, Hogan TM. Geriatric abdominal pain. In: Geriatric Medicine. 3rd ed. 1997:138-145.
Chase CW, Barker DE, Russell WL, et al. Serum amylase and lipase in the evaluation of acute abdominal pain. Am Surg. Dec 1996;62(12):1028-33. [Medline].
de Dombal FT. Acute abdominal pain in the elderly. J Clin Gastroenterol. Dec 1994;19(4):331-5. [Medline].
Fenyo G. Acute abdominal disease in the elderly: experience from two series in Stockholm. Am J Surg. Jun 1982;143(6):751-4. [Medline].
Gardner RL, Almeida R, Maselli JH, Auerbach A. Does gender influence emergency department management and outcomes in geriatric abdominal pain?. J Emerg Med. Sep 2010;39(3):275-81. [Medline].
Graff L, Russell J, Seashore J, et al. False-negative and false-positive errors in abdominal pain evaluation: failure to diagnose acute appendicitis and unnecessary surgery. Acad Emerg Med. Nov 2000;7(11):1244-55. [Medline].
Hilton D, Iman N, Burke GJ, et al. Absence of abdominal pain in older persons with endoscopic ulcers: a prospective study. Am J Gastroenterol. Feb 2001;96(2):380-4. [Medline].
Holly DC, Zachary PE Jr. Cholesterol embolization leading to small and large bowel infarction. Am J Gastroenterol. Nov 1995;90(11):2075-6. [Medline].
Horattas MC, Guyton DP, Wu D. A reappraisal of appendicitis in the elderly. Am J Surg. Sep 1990;160(3):291-3. [Medline].
Kizer KW, Vassar MJ. Emergency department diagnosis of abdominal disorders in the elderly. Am J Emerg Med. Jul 1998;16(4):357-62. [Medline].
Lee R, Tung HK, Tung PH, et al. CT in acute mesenteric ischaemia. Clin Radiol. Apr 2003;58(4):279-87. [Medline].
LoVecchio F, Oster N, Sturmann K, et al. The use of analgesics in patients with acute abdominal pain. J Emerg Med. Nov-Dec 1997;15(6):775-9. [Medline].
Marco CA, Schoenfeld CN, Keyl PM, et al. Abdominal pain in geriatric emergency patients: variables associated with adverse outcomes. Acad Emerg Med. Dec 1998;5(12):1163-8. [Medline].
Pace S, Burke TF. Intravenous morphine for early pain relief in patients with acute abdominal pain. Acad Emerg Med. Dec 1996;3(12):1086-92. [Medline].
Parker JS, Vukov LF, Wollan PC. Abdominal pain in the elderly: use of temperature and laboratory testing to screen for surgical disease. Fam Med. Mar 1996;28(3):193-7. [Medline].
Parker LJ, Vukov LF, Wollan PC. Emergency department evaluation of geriatric patients with acute cholecystitis. Acad Emerg Med. Jan 1997;4(1):51-5. [Medline].
Pilotto A, Maggi S, Noale M, Franceschi M, Parisi G, Crepaldi G. Development and validation of a new questionnaire for the evaluation of upper gastrointestinal symptoms in the elderly population: a multicenter study. J Gerontol A Biol Sci Med Sci. Feb 2010;65(2):174-8. [Medline].
Rao PM, Rhea JT, Novelline RA, et al. Helical CT with only colonic contrast material for diagnosing diverticulitis: prospective evaluation of 150 patients. AJR Am J Roentgenol. Jun 1998;170(6):1445-9. [Medline].
Reilly JM, Tilson MD. Incidence and etiology of abdominal aortic aneurysms. Surg Clin North Am. Aug 1989;69(4):705-11. [Medline].
Rusnak RA, Borer JM, Fastow JS. Misdiagnosis of acute appendicitis: common features discovered in cases after litigation. Am J Emerg Med. Jul 1994;12(4):397-402. [Medline].
Sanson TG, O'Keefe KP. Evaluation of abdominal pain in the elderly. Emerg Med Clin North Am. Aug 1996;14(3):615-27. [Medline].
Stussman BJ. National Hospital Ambulatory Medical Care Survey: 1994 emergency department summary. Adv Data. May 17 1996;1-20. [Medline].
Vermeulen B, Morabia A, Unger PF, et al. Acute appendicitis: influence of early pain relief on the accuracy of clinical and US findings in the decision to operate--a randomized trial. Radiology. Mar 1999;210(3):639-43. [Medline].
Vissers RJ, Abu-Laban RB, McHugh DF. Amylase and lipase in the emergency department evaluation of acute pancreatitis. J Emerg Med. Nov-Dec 1999;17(6):1027-37. [Medline].
Wildermuth S, Leschka S, Alkadhi H, et al. Multislice CT in the pre- and postinterventional evaluation of mesenteric perfusion. Eur Radiol. Jun 2005;15(6):1203-10. [Medline].
Woodring JH, Heiser MJ. Detection of pneumoperitoneum on chest radiographs: comparison of upright lateral and posteroanterior projections. AJR Am J Roentgenol. Jul 1995;165(1):45-7. [Medline].

