Breast Abscess and Masses Workup
- Author: Andrew C Miller, MD; Chief Editor: Rick Kulkarni, MD more...
Laboratory Studies
In patients suspected of having a breast abscess, a CBC with differential may be helpful. An aerobic and anaerobic culture may be taken during surgical drainage.
Imaging Studies
Ultrasonography is used to distinguish solid from cystic structures and to direct needle aspiration for abscess drainage. Simple cysts are seen on sonograms as round or oval with sharply defined margins and posterior acoustic enhancement. Complex cysts are characterized by a significant solid component, septations, lobulations, varied wall thickness, and the presence of internal debris. Abscesses usually appear as ill-defined masses and have central hypoechoic areas with either septations or low-level internal echoes, and posterior enhancement.[14] For more information, see Breast Cancer, Ultrasonography.
Various types of breast masses are shown in the images below.
Ultrasonogram demonstrates a hypoechoic mass with smooth, partially lobulated margins typical of a fibroadenoma.
Breast cancer, ultrasonography. Mediolateral oblique digital mammogram of the right breast in a 66-year-old woman with a new, opaque, irregular mass approximately 1 cm in diameter. The mass has spiculated margins in the middle third of the right breast at the 10-o'clock position. Image demonstrates both the spiculated mass (black arrow) and separate anterior focal asymmetry (white arrow).
Breast cancer, ultrasonography. Antiradial sonogram of the spiculated mass (shown in the image above) demonstrates a hypoechoic mass with angular margins (black arrows). Cursors on the margins of the mass were used to electronically measure its dimensions of the mass, which was 0.9 X 0.8 cm. Schedule an outpatient mammography to further characterize the suspected breast mass. The sensitivity of mammography ranges from 74-95%, and specificity ranges from 89-99%.[15, 16] Approximately 5-10% of screening examinations are interpreted as abnormal, but 90% of women with abnormal results do not have breast cancer.[15, 16] For more information, see Breast, Benign Calcifications, Breast, Fibroadenoma, Breast, Nipple Discharge Evaluation, and Breast Cancer, Mammography.
Various breast masses are shown in the mammograms below.
Craniocaudal mammograms obtained 1 year apart demonstrate a newly developing mass in the outer part of the breast.
Spot compression mammogram of the outer part of the breast demonstrates a new mass as smooth, margined, and oval. The findings are consistent with a fibroadenoma, a cyst, or a malignancy. In this patient, the diagnosis was a rapidly growing fibroadenoma.
Eggshell or rim calcifications (arrows) have walls thinner than those of lucent-centered calcifications.
This mass with associated large, coarse calcifications (arrows) is a degenerating fibroadenoma. Procedures
Ultrasound-guided needle aspirations can be performed on abscesses smaller than 3 cm; however, evidence in the literature shows that abscesses greater than 3 cm treated with needle aspiration have a high reoccurrence rate and may need further incision and drainage.[17, 18, 19]
For many years, I&D has been the standard of care for abscesses. Although I&D has a lower reoccurrence rate, it is more invasive than needle aspiration and frequently results in scarring with poor cosmetic outcomes.[20]
Dixon JM. ABC of breast diseases. Breast infection. BMJ. Oct 8 1994;309(6959):946-9. [Medline].
Dixon JM. Outpatient treatment of non-lactational breast abscesses. Br J Surg. Jan 1992;79(1):56-7. [Medline].
Whitaker-Worth DL, Carlone V, Susser WS, et al. Dermatologic diseases of the breast and nipple. J Am Acad Dermatol. Nov 2000;43(5 Pt 1):733-51; quiz 752-4. [Medline].
Bland, Copeland, eds. The Breast: Comprehensive Management of Benign and Malignant Disorders. 3rd ed. Saunders; 2004.
American Cancer Society. Breast Cancer Facts and Figures 2009-2010. American Cancer Society. Available at http://www.cancer.org/downloads/STT/F861009_final%209-08-09.pdf. Accessed Feb 1, 2010.
Givens ML, Luszczak M. Breast disorders: a review for emergency physicians. J Emerg Med. Jan 2002;22(1):59-65. [Medline].
Mass S. Breast pain: engorgement, nipple pain and mastitis. Clin Obstet Gynecol. Sep 2004;47(3):676-82. [Medline].
Efrat M, Mogilner JG, Iujtman M, et al. Neonatal mastitis--diagnosis and treatment. Isr J Med Sci. Sep 1995;31(9):558-60. [Medline].
De Silva NK, Brandt ML. Disorders of the breast in children and adolescents, Part 1: Disorders of growth and infections of the breast. J Pediatr Adolesc Gynecol. Oct 2006;19(5):345-9. [Medline].
Anderson WF, Rosenberg PS, Menashe I, Mitani A, Pfeiffer RM. Age-related crossover in breast cancer incidence rates between black and white ethnic groups. J Natl Cancer Inst. Dec 2007;100(24):1804-14. [Medline].
Armstrong K, Eisen A, Weber B. Assessing the risk of breast cancer. N Engl J Med. Feb 24 2000;342(8):564-71. [Medline].
Schafer P, Fürrer C, Mermillod B. An association of cigarette smoking with recurrent subareolar breast abscess. Int J Epidemiol. Dec 1988;17(4):810-3. [Medline].
Brennan M, Houssami N, French J. Management of benign breast conditions. Part 3--Other breast problems. Aust Fam Physician. May 2005;34(5):353-5. [Medline].
Muttarak M, Chaiwun B. Imaging of giant breast masses with pathological correlation. Singapore Med J. Mar 2004;45(3):132-9. [Medline].
Kerlikowske K, Smith-Bindman R, Ljung BM, et al. Evaluation of abnormal mammography results and palpable breast abnormalities. Ann Intern Med. Aug 19 2003;139(4):274-84. [Medline].
Kerlikowske K, Creasman J, Leung JW, et al. Differences in screening mammography outcomes among White, Chinese, and Filipino women. Arch Intern Med. Sep 12 2005;165(16):1862-8. [Medline].
Thirumalaikumar S, Kommu S. Best evidence topic reports. Aspiration of breast abscesses. Emerg Med J. 21(3);May 2004:333-4. [Medline].
Hook GW, Ikeda DM. Treatment of breast abscesses with US-guided percutaneous needle drainage without indwelling catheter placement. Radiology. 1999;213:579-82. [Medline].
Ozseker B, Ozcan UA, Rasa K, Cizmeli OM. Treatment of breast abscesses with ultrasound-guided aspiration and irrigation in the emergency setting. Emerg Radiol. Mar 2008;15(2):105-8. [Medline].
Eryilmaz R, Sahin M, Hakan Tekelioglu M, Daldal E. Management of lactational breast abscesses. Breast. Oct 2005;14(5):375-9. [Medline].
Arroyo R, Martín V, Maldonado A, Jiménez E, Fernández L, Rodríguez JM. Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin Infect Dis. Jun 2010;50(12):1551-8. [Medline]. [Full Text].
Barbosa-Cesnik C, Schwartz K, Foxman B. Lactation mastitis. JAMA. Apr 2 2003;289(13):1609-12. [Medline].
[Guideline] U.S. Preventive Services Task Force. Screening for breast cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. Nov 17 2009;151(10):716-26, W-236. [Medline]. [Full Text].
Zylstra S, D'Orsi CJ, Ricci BA, et al. Defense of breast cancer malpractice claims. Breast J. Mar-Apr 2001;7(2):76-90. [Medline].
American Cancer Society. Breast Cancer Facts & Figures 2007-2008. Available at http://www.cancer.org/downloads/STT/BCFF-Final.pdf. Accessed 04/01/2009.
August DA, Sondak VK. Breast. In: Greenfield LJ, et al, eds. Surgery Scientific Principles and Practice. 2nd ed. Lippincott-Raven Publishers; 1997:1357-1415.
Beckman C. Ling F, Barzansky B, Herbert W, Laube D, Smith R, eds. Obstetrics and Gynecology. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2009.
Dener C, Inan A. Breast abscesses in lactating women. World J Surg. Feb 2003;27(2):130-3. [Medline].
Dixon JM. Repeated aspiration of breast abscesses in lactating women. BMJ. Dec 10 1988;297(6662):1517-8. [Medline].
Eley JW, Hill HA, Chen VW, et al. Racial differences in survival from breast cancer. Results of the National Cancer Institute Black/White Cancer Survival Study. JAMA. Sep 28 1994;272(12):947-54. [Medline].
Eryilmaz R, Sahin M, Hakan Tekelioglu M, Daldal E. Management of lactational breast abscesses. Breast. Oct 2005;14(5):375-9. [Medline].
Garcia CJ, Espinoza A, Dinamarca V, et al. Breast US in children and adolescents. Radiographics. Nov-Dec 2000;20(6):1605-12. [Medline].
Harris JR, Lippman ME, Veronesi U, et al. Breast cancer (1). N Engl J Med. Jul 30 1992;327(5):319-28. [Medline].
Houssami N, Ciatto S, Ambrogetti D, Catarzi S, Risso G, Bonardi R, et al. Florence-Sydney Breast Biopsy Study: sensitivity of ultrasound-guided versus freehand fine needle biopsy of palpable breast cancer. Breast Cancer Res Treat. Jan 2005;89(1):55-9. [Medline]. [Full Text].
Karstrup S, Solvig J, Nolsoe CP, et al. Acute puerperal breast abscesses: US-guided drainage. Radiology. 1993;188:807-9. [Medline].
Khoda J, Lantsberg L, Yegev Y, et al. Management of periareolar abscess and mamillary fistula. Surg Gynecol Obstet. Oct 1992;175(4):306-8. [Medline].
Kitchen PR. Management of sub-areolar abscess and mammary fistula. Aust N Z J Surg. Apr 1991;61(4):313-5. [Medline].
Lau SK, McKee GT, Weir MM, Tambouret RH, Eichhorn JH, Pitman MB. The negative predicative value of breast fine-needle aspiration biopsy: the Massachusetts General Hospital experience. Breast J. Nov-Dec 2004;10(6):487-91. [Medline].
Maier WP, Au FC, Tang CK. Nonlactational breast infection. Am Surg. Apr 1994;60(4):247-50. [Medline].
Meguid MM, Oler A, Numann PJ, et al. Pathogenesis-based treatment of recurring subareolar breast abscesses. Surgery. Oct 1995;118(4):775-82. [Medline].
Miller BA, Feuer EJ, Hankey BF. The significance of the rising incidence of breast cancer in the United States. Important Adv Oncol. 1994;193-207. [Medline].
O'Hara RJ, Dexter SP, Fox JN. Conservative management of infective mastitis and breast abscesses after ultrasonographic assessment. Br J Surg. Oct 1996;83(10):1413-4. [Medline].
Surveillance, Epidemiology, and End Results (SEER) Program, SEER 17 Registries, 2000-2004 [database online]. SEER.cancer.gov: Division of Cancer Control and Population Science, National Cancer Institute; 2007.
Walker AP, Edmiston CE, Krepel CJ, et al. A prospective study of the microflora of nonpuerperal breast abscess. Arch Surg. 1988;123:908-11. [Medline].
Watt-Boolsen S, Rasmussen NR, Blichert-Toft M. Primary periareolar abscess in the nonlactating breast: risk of recurrence. Am J Surg. Jun 1987;153(6):571-3. [Medline].
Wiesenfeld HC, Sweet RL. Perinatal infections. In: Scott JR, et al, eds. Danforth's Obstetrics and Gynecology. 7th ed. Lippincott-Raven Publishers; 1994:469.

