Body Fluid Exposures Follow-up
- Author: Nathalie Mathieu, MD; Chief Editor: Rick Kulkarni, MD more...
Further Outpatient Care
If the source patient is positive for HBV, HCV, and/or HIV, repeatedly test the exposed caregiver at timed intervals of 0, 3 months, and 6 months. This requires close and reliable follow-up mechanisms, such as Occupational Health Services or primary care physicians.
Deterrence/Prevention
OSHA standards are to be encouraged and reinforced by all hospital employees consistently because prevention is the single best weapon against blood/body fluid exposures.
The following universal precautions should be followed in all patient contact situations:
- Wash hands between care of each patient.
- Use gloves when handling body fluids or performing procedures where exposure is possible, including contact with mucous membranes.
- Use protective gowns, eyewear, and masks during procedures when risk of splash or spray of body fluids exists.
- Never recap needles. If recapping is necessary, the cap should not be held by hand, rather lay the cap on a firm surface and insert the needle. Then, the entire system is lifted, and the cap is secured in place.
OSHA requirements are now moving toward needleless and needlestick prevention systems as basic requirements in health care facilities. Institutions must evaluate these systems and utilize those that function best within their departments.
Wearing gloves may reduce (>50%) the volume of blood introduced through the injury.
Complications
Infection is still a significant concern at any given exposure, especially those involving disruption of the normal integumentary barrier. Antibiotic prophylaxis should be considered.
Prognosis
Prognosis is associated with risk of infection and its sequelae. This is difficult to specify in any given patient. However, given the risk of HIV transmission of less than 1%, the prognosis of any given exposed patient may be listed as good but may only remain so with vigilant follow-up and consistent use of prophylaxis against infection.
Patient Education
For excellent patient education resources, visit eMedicine's Public Health Center and Sexually Transmitted Diseases Center. Also, see eMedicine's patient education articles Hepatitis B, Hepatitis C, and HIV/AIDS.
Simard EP, Miller JT, George PA, et al. Hepatitis B vaccination coverage levels among healthcare workers in the United States, 2002-2003. Infect Control Hosp Epidemiol. Jul 2007;28(7):783-90. [Medline]. [Full Text].
Kamili S, Krawczynski K, McCaustland K, Li X, Alter MJ. Infectivity of hepatitis C virus in plasma after drying and storing at room temperature. Infect Control Hosp Epidemiol. May 2007;28(5):519-24. [Medline].
van Tongeren M, Mee T, Whatmough P, Broad L, Maslanyj M, Allen S. Assessing occupational and domestic ELF magnetic field exposure in the uk adult brain tumour study: results of a feasibility study. Radiat Prot Dosimetry. 2004;108(3):227-36. [Medline]. [Full Text].
New York State Department of Health AIDS Institute. Recommendations for HIV Postexposure Prophylaxis (PEP). 2008. Available at http://www.hivguidelines.org.
Henderson DK, Fahey BJ, Willy M, Schmitt JM, Carey K, Koziol DE. Risk for occupational transmission of human immunodeficiency virus type 1 (HIV-1) associated with clinical exposures. A prospective evaluation. Ann Intern Med. Nov 15 1990;113(10):740-6. [Medline].
[Guideline] Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep. Sep 30 2005;54:1-17. [Medline].
Merchant RC, Nettleton JE, Mayer KH, Becker BM. Blood or body fluid exposures and HIV postexposure prophylaxis utilization among first responders. Prehosp Emerg Care. Jan-Mar 2009;13(1):6-13. [Medline].
National Institutes of health consensus development conference statement: management of hepatitis C. June 10-12, 2002. Available at http://consensus.nih.gov/2002/2002hepatitisc2002116html.htm.
Landovitz RJ, Currier JS. Clinical practice. Postexposure prophylaxis for HIV infection. N Engl J Med. Oct 29 2009;361(18):1768-75. [Medline].
[Guideline] Boyce JM, Pittet D. Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep. Oct 25 2002;51:1-45, quiz CE1-4. [Medline].
Mallin R, Sinclair D. Needlestick injuries and potential body fluid exposure in the emergency department. CJEM. Jan 2003;5(1):36-7. [Medline]. [Full Text].
Nguyen CT, Tran TT. Hepatitis vaccination and prophylaxis. Clin Liver Dis. May 2009;13(2):317-29. [Medline].
Alter MJ. Occupational exposure to hepatitis C virus: a dilemma. Infect Control Hosp Epidemiol. Dec 1994;15(12):742-4. [Medline].
[Guideline] CDC. Guidelines for prevention of transmission of human immunodeficiency virus and hepatitis B virus to health-care and public-safety workers. MMWR Morb Mortal Wkly Rep. Jun 23 1989;38 Suppl 6:1-37. [Medline].
[Guideline] CDC. Protection against viral hepatitis. Recommendations of the Immunization Practices Advisory Committee (ACIP). MMWR Recomm Rep. Feb 9 1990;39:1-26. [Medline].
[Guideline] CDC. Public Health Service guidelines for the management of health-care worker exposures to HIV and recommendations for postexposure prophylaxis. Centers for Disease Control and Prevention. MMWR Recomm Rep. May 15 1998;47:1-33. [Medline].
Gerberding JL, Henderson DK. Management of occupational exposures to bloodborne pathogens: hepatitis B virus, hepatitis C virus, and human immunodeficiency virus. Clin Infect Dis. Jun 1992;14(6):1179-85. [Medline].
Kiyosawa K, Sodeyama T, Tanaka E, et al. Hepatitis C in hospital employees with needlestick injuries. Ann Intern Med. Sep 1 1991;115(5):367-9. [Medline].
Lanphear BP. Trends and patterns in the transmission of bloodborne pathogens to health care workers. Epidemiol Rev. 1994;16(2):437-50. [Medline].
Marcus R. Surveillance of health care workers exposed to blood from patients infected with the human immunodeficiency virus. N Engl J Med. Oct 27 1988;319(17):1118-23. [Medline].
Mast ST, Woolwine JD, Gerberding JL. Efficacy of gloves in reducing blood volumes transferred during simulated needlestick injury. J Infect Dis. Dec 1993;168(6):1589-92. [Medline].
Mauskopf JA, Bradley CJ, French MT. Benefit-cost analysis of hepatitis B vaccine programs for occupationally exposed workers. J Occup Med. Jun 1991;33(6):691-8. [Medline].
Merchant RC, Becker BM, Mayer KH, Fuerch J, Schreck B. Emergency department blood or body fluid exposure evaluations and HIV postexposure prophylaxis usage. Acad Emerg Med. Dec 2003;10(12):1345-53. [Medline].
Jagger J. Risky procedures, risky devices, risky job. Adv in Exposure Prev. 1994;1:4-6.
Robert LM, Bell DM. HIV transmission in the health-care setting. Risks to health-care workers and patients. Infect Dis Clin North Am. Jun 1994;8(2):319-29. [Medline].
Stewardson DA, Burke FJ, Elkhazindar MM, et al. The incidence of occupational exposures among students in four UK dental schools. Int Dent J. Feb 2004;54(1):26-32. [Medline].
Vu T. Standardization of Body Surface Area Calculations. 1999. halls.md. Available at http://www.halls.md/bsa/bsaVuReport.htm.

