Management of Acute Presentation of Mumps
- Author: Kristin A Carmody, MD; Chief Editor: Rick Kulkarni, MD more...
Workup
Diagnosis is usually clinical. Laboratory evaluation is usually undertaken in the emergency department (ED) to look for other causes of a patient's symptoms or to evaluate for complications or comorbidity. Mumps-specific tests are generally performed on an outpatient basis.
Go to Mumps for complete information on this topic.
Treatment & Management
Supportive Care and Management of Comorbidity
Supportive care and outpatient follow-up are usually all that is needed for patients with mumps in cases of straightforward infection. Persons exposed to the virus should be counseled on vaccination and risks.
Complications due to mumps should be treated based on presentation:
- Orchitis - Testicular ultrasonography; ice packs applied to the scrotal area for swelling; discharge with scrotal support and anti-inflammatory agents
- Severe pancreatitis - Intravenous hydration
- Symptomatic meningitis or encephalitis -Lumbar puncture
A live-virus vaccine should be subcutaneously administered, in the form of the combination MMR (mumps-measles-rubella) vaccination. Antibodies develop in 95% of all susceptible persons after a single dose.
Vaccination
MMR vaccine should be given routinely to children aged 12-15 months. A second dose of MMR vaccine is recommended for those aged 4-6 years in accordance with recommendations for routine measles vaccination. If this dose is missed, it should be given before age 12 years.
Revaccination is indicated because mumps can occur in highly vaccinated populations. MMR vaccine is not harmful if given to a patient already immune to one or more of the other viruses.
Mumps vaccination is imperative for patients approaching adolescence and adulthood. Persons should be considered susceptible unless they have documentation of at least 1 dose of vaccine on or after the first birthday, documentation of physician-diagnosed mumps, serologic evidence of immunity, or a birth date before 1957. Vaccination should be offered to patients before they travel, even though it is not a requirement of entry to many countries.
Precautions and contraindications to vaccination include the following:
- Children with minor illnesses with or without fever can be vaccinated.
- Allergic reactions to vaccination occasionally occur but tend to be minor.
- Most children with egg sensitivity can be safely vaccinated.
- Skin testing with MMR vaccine does not reliably predict which children will have a hypersensitivity reaction.
Live mumps vaccine should be given 2 weeks before or 3 months after administration of immunoglobulin or blood transfusion because of the theoretical possibility that the antibody will neutralize the vaccine virus and inhibit a successful immunization. Standard immune globulin is ineffective against mumps.
Patients with immunodeficiencies (eg, those on large doses of steroids, radiation, or chemotherapy) should not receive live-virus vaccine. The exceptions are patients with symptomatic HIV who are not severely immunocompromised; these patients should receive MMR vaccine. Vaccinating close susceptible contacts can reduce the risk of exposure for patients with altered immunity. Vaccines should not be administered during pregnancy.
Medscape Reference. Available at http://emedicine.medscape.com/. Accessed April 6, 2011.

