eMedicine Specialties > Emergency Medicine > Infectious Diseases
Salmonella Infection: Follow-up
Updated: Apr 3, 2009
Follow-up
Further Outpatient Care
- Follow-up treatment with the patient's primary care physician is highly recommended.
- Worsening symptoms warrant a return visit to the ED.
- Antibiotic treatment for a chronic carrier in coordination with the patient’s primary care physician may be indicated. Asymptomatic carriage occurs on average for about 5 weeks, with prolonged duration existing in children younger than 5 years.28
Deterrence/Prevention
- Proper hygiene and food storage
- Keep raw meat and poultry away from unprepared foods
- Clean surfaces, utensils, and hands after contact with raw foods
- Myrtle leaves oil has shown promise as an alternative disinfectant.29
- Avoid eating raw or undercooked eggs
- Salmonella can withstand temperatures as high as 194o F (90o C) for 50 minutes.10
- Control of animal reservoir
- Vaccine for enteric or typhoid fever
Complications
- Hypovolemic shock
- Urinary retention
- Metastatic abscess formation
- Acute or chronic hydrocephalus
- Meningitis
- Psychosis
- Cholecystitis
- Toxic megacolon
- Intestinal perforation
- Septic thrombophlebitis
- Mycotic abdominal aortic aneurysm
- Myocarditis
- Nephritis
- Osteomyelitis
- An asymptomatic chronic carrier state
- DIC in infants with typhoid fever30
Prognosis
- Nontyphoid Salmonella is generally self-limiting.
- Most patients are treated on an outpatient basis.
- Extremes of age and an immunocompromised state increases morbidity and mortality.
- Typhoid Salmonella generally requires treatment.
Patient Education
- Emphasize good hand-washing, thorough cleaning of cooking utensils, appropriate food preparation techniques, and adequate cooking temperature for killing the bacteria.
Miscellaneous
Medicolegal Pitfalls
- Failure to aggressively manage patients who are immunocompromised, extremes of age, or have complicating factors such as sickle-cell disease or prosthetic grafts
- Failure to recognize an extraintestinal manifestation
- Failure to query about recent travel to underdeveloped nations
- Failure to ask about previous gastric surgery, use of antacids and H2 antagonists, or any predisposition toward reduced stomach acid production
- Failure to consider alternative diagnoses - Perforated viscous and atypical presentation of appendicitis needs to be considered.
- Failure to recognize that a sudden outbreak of Salmonella may be secondary to an intentional contamination31
The authors and editors of eMedicine gratefully acknowledge the contributions of previous author, Robert A Barrali Jr, MD, to the development and writing of this article. We would like to acknowledge the assistance of Michelle Manfredi in researching this topic.
More on Salmonella Infection |
| Overview: Salmonella Infection |
| Differential Diagnoses & Workup: Salmonella Infection |
| Treatment & Medication: Salmonella Infection |
Follow-up: Salmonella Infection |
| Multimedia: Salmonella Infection |
| References |
| « Previous Page | Next Page » |
References
Coburn B, Grassl GA, Finlay BB. Salmonella, the host and disease: a brief review. Immunol Cell Biol. Feb-Mar 2007;85(2):112-8. [Medline].
Grassl GA, Finlay BB. Pathogenesis of enteric Salmonella infections. Curr Opin Gastroenterol. Jan 2008;24(1):22-6. [Medline].
Chambers HF. McPhee SJ, Papadakis MA, Tierney LM, eds. Current Medical Diagnosis & Treatment. 47th ed. McGraw-Hill Co; 2008:1250-1252.
Centers for Disease Control and Prevention. Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food--10 states, 2007. MMWR Morb Mortal Wkly Rep. Apr 11 2008;57(14):366-70. [Medline].
Linam WM, Gerber MA. Changing epidemiology and prevention of Salmonella infections. Pediatr Infect Dis J. Aug 2007;26(8):747-8. [Medline].
Peques DA, Ohl M, Miller S. Mandell, Douglas, and Bennett's: Principles and Practice of Infectious Diseases. 6th ed. Elsevier; 2005:chap 220.
Braden CR. Salmonella enterica serotype Enteritidis and eggs: a national epidemic in the United States. Clin Infect Dis. Aug 15 2006;43(4):512-7. [Medline].
Jones TF, Ingram LA, Fullerton KE, et al. A case-control study of the epidemiology of sporadic Salmonella infection in infants. Pediatrics. Dec 2006;118(6):2380-7. [Medline].
Centers for Disease Control and Prevention. Multistate outbreak of human Salmonella infections caused by contaminated dry dog food--United States, 2006-2007. MMWR Morb Mortal Wkly Rep. May 16 2008;57(19):521-4. [Medline].
Centers for Disease Control and Prevention. Multistate outbreak of Salmonella infections associated with peanut butter and peanut butter-containing products--United States, 2008-2009. MMWR Morb Mortal Wkly Rep. Feb 6 2009;58(4):85-90. [Medline].
Voetsch AC, Van Gilder TJ, Angulo FJ, et al. FoodNet estimate of the burden of illness caused by nontyphoidal Salmonella infections in the United States. Clin Infect Dis. Apr 15 2004;38 Suppl 3:S127-34. [Medline].
Weinberger M, Keller N. Recent trends in the epidemiology of non-typhoid Salmonella and antimicrobial resistance: the Israeli experience and worldwide review. Curr Opin Infect Dis. Dec 2005;18(6):513-21. [Medline].
Boyle EC, Bishop JL, Grassl GA, et al. Salmonella: from pathogenesis to therapeutics. J Bacteriol. Mar 2007;189(5):1489-95. [Medline].
Sethuraman U, Kamat D. Management of child with fever after international travel. Clin Pediatr (Phila). Apr 2007;46(3):222-7. [Medline].
Heymann DL. Control of Communicable Diseases Manual. 18th ed. American Public Health Association; 2004:469-473.
Perera N, Geary C, Wiselka M, et al. Mixed Salmonella infection: case report and review of the literature. J Travel Med. Mar-Apr 2007;14(2):134-5. [Medline].
Hatta M, Smits HL. Detection of Salmonella typhi by nested polymerase chain reaction in blood, urine, and stool samples. Am J Trop Med Hyg. Jan 2007;76(1):139-43. [Medline].
Bottieau E, Clerinx J, Van den Enden E, et al. Fever after a stay in the tropics: diagnostic predictors of the leading tropical conditions. Medicine (Baltimore). Jan 2007;86(1):18-25. [Medline].
Abubakar I, Irvine L, Aldus CF, et al. A systematic review of the clinical, public health and cost-effectiveness of rapid diagnostic tests for the detection and identification of bacterial intestinal pathogens in faeces and food. Health Technol Assess. Sep 2007;11(36):1-216. [Medline].
Sirinavin S, Garner P. Antibiotics for treating salmonella gut infections. Cochrane Database Syst Rev. 2000;CD001167. [Medline].
Wistrom J, Jertborn M, Ekwall E, et al. Empiric treatment of acute diarrheal disease with norfloxacin. A randomized, placebo-controlled study. Swedish Study Group. Ann Intern Med. Aug 1 1992;117(3):202-8. [Medline].
Centers for Disease Control and Prevention. National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS): Human Isolates Final Report, 2004. [Full Text].
[Best Evidence] Thaver D, Zaidi AK, Critchley JA, Azmatullah A, Madni SA, Bhutta ZA. Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). Cochrane Database Syst Rev. Oct 8 2008;CD004530. [Medline].
Parry CM, Threlfall EJ. Antimicrobial resistance in typhoidal and nontyphoidal salmonellae. Curr Opin Infect Dis. Oct 2008;21(5):531-8. [Medline].
Grady R. Safety profile of quinolone antibiotics in the pediatric population. Pediatr Infect Dis J. Dec 2003;22(12):1128-32. [Medline].
Threlfall EJ, de Pinna E, Day M, Lawrence J, Jones J. Alternatives to ciprofloxacin use for enteric Fever, United kingdom. Emerg Infect Dis. May 2008;14(5):860-1. [Medline].
Molbak K. Human health consequences of antimicrobial drug-resistant Salmonella and other foodborne pathogens. Clin Infect Dis. Dec 1 2005;41(11):1613-20. [Medline].
Buchwald DS, Blaser MJ. A review of human salmonellosis: II. Duration of excretion following infection with nontyphi Salmonella. Rev Infect Dis. May-Jun 1984;6(3):345-56. [Medline].
Gunduz GT, Gonul SA, Karapinar M. Efficacy of myrtle oil against Salmonella Typhimurium on fresh produce. Int J Food Microbiol. Mar 31 2009;130(2):147-50. [Medline].
Bhutta ZA. Current concepts in the diagnosis and treatment of typhoid fever. BMJ. Jul 8 2006;333(7558):78-82. [Medline].
Torok TJ, Tauxe RV, Wise RP, et al. A large community outbreak of salmonellosis caused by intentional contamination of restaurant salad bars. JAMA. Aug 6 1997;278(5):389-95. [Medline].
Amieva MR. Important bacterial gastrointestinal pathogens in children: a pathogenesis perspective. Pediatr Clin North Am. Jun 2005;52(3):749-77, vi. [Medline].
Connor BA, Schwartz E. Typhoid and paratyphoid fever in travellers. Lancet Infect Dis. Oct 2005;5(10):623-8. [Medline].
Hoffman SL, Punjabi NH, Kumala S, et al. Reduction of mortality in chloramphenicol-treated severe typhoid fever by high-dose dexamethasone. N Engl J Med. Jan 12 1984;310(2):82-8. [Medline].
Parry CM, Hien TT, Dougan G, et al. Typhoid fever. N Engl J Med. Nov 28 2002;347(22):1770-82. [Medline].
Punjabi NH, Hoffman SL, Edman DC, et al. Treatment of severe typhoid fever in children with high dose dexamethasone. Pediatr Infect Dis J. Aug 1988;7(8):598-600. [Medline].
Further Reading
Keywords
Salmonella, salmonella infection, salmonella gastroenteritis, salmonellosis, typhi, typhoid fever, enteric fever, typhimurium, enteritidis, choleraesuis, Salmonella infection, severe diarrhea, food-borne illness
Follow-up: Salmonella Infection