Herpetic Whitlow Follow-up
- Author: Michael S Omori, MD; Chief Editor: Steven C Dronen, MD, FAAEM more...
Further Outpatient Care
- Advise routine outpatient follow-up care to ensure resolution of infection and to monitor for evidence of bacterial superinfection.
Inpatient & Outpatient Medications
- Include analgesics in the treatment of herpetic whitlow.
- Topical acyclovir may be of benefit in primary infections.[5]
- In cases of superinfection, use antibiotics effective against skin pathogens.
Deterrence/Prevention
- Avoidance of exposure is key to the prevention of herpetic whitlow.
- Health care workers should use gloves, practice strict hand washing, and scrupulously observe universal fluid precautions.[2]
- Studies have demonstrated herpes virus in 2.5% of asymptomatic patients and in 6.5% of hospitalized patients with tracheostomies.
- Caution patients with oral, labial, or genital lesions and the parents and caregivers of children with lesions against digital contact with lesions.
Complications
- Complications usually are minimal provided that affected patients are immunocompetent.
- Misdiagnosis as a bacterial paronychia or felon with resultant deep incision may lead to delayed resolution, increased risk of bacterial superinfection, systemic spread (rare), and possibly development of herpes encephalitis.
- Hyperesthesia or numbness has been reported in 30-50% of patients between episodes of reactivation.
- Other potential complications include scarring of the affected digit and ocular spread.
Prognosis
- Prognosis is excellent in uncomplicated cases, with spontaneous resolution in 3-4 weeks.
Patient Education
- Advise patients of the likelihood of future recurrence and warn of the possibility of disease spreading to other parts of the body and to other individuals.
Wu IB, Schwartz RA. Herpetic whitlow. Cutis. Mar 2007;79(3):193-6. [Medline].
Klotz RW. Herpetic whitlow: an occupational hazard. AANA J. Feb 1990;58(1):8-13. [Medline].
Robayna MG, Herranz P, Rubio FA, Pena P, Pena JM, Gonzalez J, et al. Destructive herpetic whitlow in AIDS: report of three cases. Br J Dermatol. Nov 1997;137(5):812-5. [Medline].
El Hachem M, Bernardi S, Giraldi L, Diociaiuti A, Palma P, Castelli-Gattinara G. Herpetic whitlow as a harbinger of pediatric HIV-1 infection. Pediatr Dermatol. Mar-Apr 2005;22(2):119-21. [Medline].
Nikkels AF, Pierard GE. Treatment of mucocutaneous presentations of herpes simplex virus infections. Am J Clin Dermatol. 2002;3(7):475-87. [Medline].
Cunha BA, ed. Antibiotic Essentials. 7th ed. Sudbury, Mass: Physician's Press; 2008:109.
Weisman E, Troncale JA. Herpetic whitlow: a case report. J Fam Pract. Nov 1991;33(5):516, 520. [Medline].

