eMedicine Specialties > Emergency Medicine > Neurology

Brown-Sequard Syndrome: Follow-up

Author: Michael S Beeson, MD, MBA, FACEP, Professor of Emergency Medicine, Northeastern Ohio Universities College of Medicine; Program Director, Emergency Medicine Residency, Summa Health System
Contributor Information and Disclosures

Updated: Dec 17, 2008

Follow-up

Transfer

  • Transfer to a level I trauma center or to a facility with expertise in the care of spinal cord injuries is appropriate; however, transfer should not impede the overall evaluation of these patients, including assessment for possible other injuries.

Complications

  • Complications associated with spinal injury may be present. These may include hypotension initially ("spinal shock") to pulmonary emboli if not prophylactically treated. Subacute and chronic care periods may be complicated by infection to sites such as lungs, urine, etc. Depression frequently occurs in patients with spinal cord injuries and should be observed for in these patients.

Prognosis

  • The prognosis for Brown-Séquard syndrome is poor and depends to a large degree on the etiology of the syndrome. Early treatment with high-dose steroids has shown benefit.

Miscellaneous

Medicolegal Pitfalls

  • Failure to realize that a cord lesion may be partial instead of complete, for example, in the anterior cord, central cord, or as in Brown-Séquard syndrome
    • Try to differentiate levels of sensation loss, motor loss, temperature loss, and vibratory sense loss.
    • Evaluate bilateral versus unilateral neurologic findings when determining level of loss.
  • Failure to consider other injuries, if the cause was traumatic, while focusing only on the spinal cord injury
    • One area commonly neglected is the abdomen; the possibility of intra-abdominal injury must be considered.
    • Always consider imaging of the abdomen/pelvis when the spinal cord is injured.
  • Failure to recognize that hypotension may be the result of something other than neurogenic shock: If the cause of spinal injury is traumatic, always consider hemorrhagic causes of hypotension before assuming it is neurogenic shock.
  • Failure to administer steroids in a timely manner: Initiate steroids promptly on the basis of the initial ED evaluation.
 


More on Brown-Sequard Syndrome

Overview: Brown-Sequard Syndrome
Differential Diagnoses & Workup: Brown-Sequard Syndrome
Treatment & Medication: Brown-Sequard Syndrome
Follow-up: Brown-Sequard Syndrome
References

References

  1. Lipper MH, Goldstein JH, Do HM. Brown-Sequard syndrome of the cervical spinal cord after chiropractic manipulation. AJNR Am J Neuroradiol. Aug 1998;19(7):1349-52. [Medline].

  2. Domenicucci M, Ramieri A, Salvati M, Brogna C, Raco A. Cervicothoracic epidural hematoma after chiropractic spinal manipulation therapy. Case report and review of the literature. J Neurosurg Spine. Nov 2007;7(5):571-4. [Medline].

  3. Egido Herrero JA, Saldana C, Jimenez A, et al. Spontaneous cervical epidural hematoma with Brown-Sequard syndrome and spontaneous resolution. Case report. J Neurosurg Sci. Apr-Jun 1992;36(2):117-9. [Medline].

  4. Ellger T, Schul C, Heindel W, et al. Idiopathic spinal cord herniation causing progressive Brown-Sequard syndrome. Clin Neurol Neurosurg. Jun 2006;108(4):388-91. [Medline].

  5. Finelli PF, Leopold N, Tarras S. Brown-Sequard syndrome and herniated cervical disc. Spine. May 1992;17(5):598-600. [Medline].

  6. Hancock JB, Field EM, Gadam R. Spinal epidural hematoma progressing to Brown-Sequard syndrome: report of a case. J Emerg Med. May-Jun 1997;15(3):309-12. [Medline].

  7. Harris P. Stab wound of the back causing an acute subdural haematoma and a Brown-Sequard neurological syndrome. Spinal Cord. Nov 2005;43(11):678-9. [Medline].

  8. Henderson SO, Hoffner RJ. Brown-Sequard syndrome due to isolated blunt trauma. J Emerg Med. Nov-Dec 1998;16(6):847-50. [Medline].

  9. Hwang W, Ralph J, Marco E, Hemphill JC 3rd. Incomplete Brown-Sequard syndrome after methamphetamine injection into the neck. Neurology. Jun 24 2003;60(12):2015-6. [Medline].

  10. Kraus JA, Stuper BK, Berlit P. Multiple sclerosis presenting with a Brown-Sequard syndrome. J Neurol Sci. 1998;156(1):112-3. [Medline].

  11. Lee JK, Kim YS, Kim SH. Brown-Sequard syndrome produced by cervical disc herniation with complete neurologic recovery: report of three cases and review of the literature. Spinal Cord. Nov 2007;45(11):744-8. [Medline].

  12. Lim E, Wong YS, Lo YL, Lim SH. Traumatic atypical Brown-Sequard syndrome: case report and literature review. Clin Neurol Neurosurg. Apr 2003;105(2):143-5. [Medline].

  13. Mastronardi L, Ruggeri A. Cervical disc herniation producing Brown-Sequard syndrome: case report. Spine. Jan 15 2004;29(2):E28-31. [Medline].

  14. Miyake S, Tamaki N, Nagashima T, et al. Idiopathic spinal cord herniation. Report of two cases and review of the literature. J Neurosurg. Feb 1998;88(2):331-5. [Medline].

  15. Moon SJ, Lee JK, Kim TW, Kim SH. Idiopathic transverse myelitis presenting as the Brown-Sequard syndrome. Spinal Cord. Mar 11 2008;[Medline].

  16. Rumana CS, Baskin DS. Brown-Sequard syndrome produced by cervical disc herniation: Case report and literature review. Surg Neurol. 1996;45(4):359-361. [Medline].

  17. Stephen AB, Stevens K, Craigen MA, Kerslake RW. Brown-Sequard syndrome due to traumatic brachial plexus root avulsion. Injury. Oct 1997;28(8):557-8. [Medline].

Further Reading

Keywords

spinal cord lesion, Brown-Sequard's syndrome, Brown-Séquard syndrome, Brown-Séquard's syndrome, Brown-Sequard paralysis, Brown-Séquard paralysis, Brown-Séquard's paralysis, hemisection of the spinal cord, ipsilateral hemiplegia, penetrating injury to the spine, incomplete spinal cord lesion

Contributor Information and Disclosures

Author

Michael S Beeson, MD, MBA, FACEP, Professor of Emergency Medicine, Northeastern Ohio Universities College of Medicine; Program Director, Emergency Medicine Residency, Summa Health System
Michael S Beeson, MD, MBA, FACEP is a member of the following medical societies: American College of Emergency Physicians, Council of Emergency Medicine Residency Directors, National Association of EMS Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Medical Editor

Samuel M Keim, MD, Associate Professor, Department of Emergency Medicine, University of Arizona College of Medicine
Samuel M Keim, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, American Medical Association, American Public Health Association, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

J Stephen Huff, MD, Associate Professor, Emergency Medicine and Neurology, Department of Emergency Medicine, University of Virginia Health Sciences Center
J Stephen Huff, MD is a member of the following medical societies: American Academy of Emergency Medicine, American Academy of Neurology, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

CME Editor

John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center
John D Halamka, MD, MS is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Phi Beta Kappa, and Society for Academic Emergency Medicine
Disclosure: Nothing to disclose.

Chief Editor

Jonathan Adler, MD, Attending Physician, Department of Emergency Medicine, Massachusetts General Hospital; Division of Emergency Medicine, Harvard Medical School
Jonathan Adler, MD is a member of the following medical societies: American Academy of Emergency Medicine and Society for Academic Emergency Medicine
Disclosure: eMedicine.com, Inc. Consulting fee Consulting

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.